ppa026722m, ppa026722m (mRNA) Prunus persica

Query:   25 AEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAA--WVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSG------------SGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++   +  SDEV GLD +LS+ A   Y  S   + +N +A  W   + DE  +HKRLK+  S +    + G+N  SLYSG            + S     L+SLPR+HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK HAS+LL ELRANA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG I P      TA+  +K+EAL LVYEICP I+FGHFVANASILEAFEGE+  HV+DLGMTLGL HG QWR LI SLANRAG+P  RLRITGVG   +R + IG +L+ +AQ + +N +                            ILQLHC+VKESRGALNSVLQ +++LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSL+AMLPKYDTRRAK+EQFYFGEEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL ++  CEGY ++E+KGCLV GWKSKPI+A SCWK
Sbjct:    3 SDLLSEERSDEVSGLDTSLSAQAY--YSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIA---ESIGSN-SSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWE-KKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLD----------------------------ILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWK 490          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLE-INTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            KLV QLI CA+ VA RDK+HAS LL ELRANA VFGTSFQRVASCFVQGLSDRL+LIQ LGAVG+ G   K+   + EK+EA  L +EICPQIQFGH  ANASILEAFEGESSVHV+DLGM LG P G QWR+L+ SLANRAG+P   L+ITGVG +AE L+ I ++L+++A+S+ +NF+FS                             LHC+VKESRGALNSVLQ + +LSPK ++LVEQD SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNI+SCEG A                 AGFQ +P+KMI +A +WLE +  C+GYT+V++KGCLV GWKSKPIIA SCWK
Sbjct:    2 KLVHQLITCAKVVAFRDKSHASALLSELRANALVFGTSFQRVASCFVQGLSDRLSLIQSLGAVGVGGCTVKTMDITPEKEEAFRLFFEICPQIQFGHLAANASILEAFEGESSVHVVDLGMNLGSPQGQQWRSLMHSLANRAGKPPSSLQITGVGTAAECLKDIIDELEVYAESLGMNFQFS----------------------------MLHCVVKESRGALNSVLQKIRELSPKAVVLVEQDASHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGSARVERHQRLDQWRRRMSRAGFQSSPMKMITEAKQWLEKVKLCDGYTIVDEKGCLVLGWKSKPIIAASCWK 345          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLAL-IQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANR-AGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAVA  D   A   L+ L       G S QRVASCF + LS RLA  + P  +     P       S E  +   ++Y+ CP I+F HF AN +I EAFE E  VHVIDL +      GYQW   I +LA R  G P   LRITGVG S E ++  G  L   A S+ + FEF  V    E+LKP  FN   G+ L VNS  +LH   +     L ++L  +   +P ++ +VEQ+ SHNGP+FLGRF+EALH YSAIFDSLDA  P    +RAK+EQ+ F   I+NIV+CEG                    GFQ  PL    + Q+   L + +C+GY + EDKGCL+ GW+ + I+A S W+
Sbjct:  302 QLVHFLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLTPKPSTSTTKPFNPFPPNSLEILKIYQILYQACPYIKFAHFTANQAIFEAFEAEERVHVIDLDIL----QGYQWPAFIQALAARPGGAPF--LRITGVGCSPESVRETGRCLTELAHSLHVPFEFHPVGEELEDLKPHMFNRRVGEALAVNSANRLH---RVPTNFLGNLLAMIRDQAPNIVTIVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKLEQYIFAPVIRNIVACEGAERVMRHERLEKWRKLMEGKGFQGVPLSANAVTQSKILLGLYSCDGYRLTEDKGCLLLGWQDRAILAASAWR 667          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEAL--HLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCL-------VKESRGA-----------LNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKM--IAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L++ L+ACA  VA     +A+  L  +   A   G + QR+A+ F + L+DR+    P    GL   +  ST  S+  +E L   L +E+CP ++  + + N +I+EA EGE  VH+IDL          QW NL+ SL+ R   P H LRITG+    E L  +   L   A+ + + F+F+ + S  ENL  +   +  G+ L ++S+LQLH L       V +S  A           + S L  L  LSPKLM++ EQ++++N P  + R MEAL+ Y+A+FD L++ L +    R K+E+  FGEEIKNI++CEGP                  AGF   PL    + QA + L     +GY + E+ GCLV  W+ +P+ + S W+
Sbjct:   49 LIRLLVACANHVAAGSIENANIGLEHISHLASPDGDTVQRIAAYFTEALADRMLKGWP----GLHKALN-STKISSISEEILVQKLFFELCPFLKLSYVITNQAIIEAMEGEKMVHIIDLNSF----ESAQWINLLQSLSARPEGPPH-LRITGIHEQKEVLDLMALQLTKEAEKLDIPFQFNPIVSKLENLDFESLRVKTGEALAISSVLQLHTLLAIDDEMVGKSPSASKNTSAVHLQRMGSFLAALWGLSPKLMVVTEQESNNNCPTLMERVMEALNFYAALFDCLESTLSRASIERQKVEKMLFGEEIKNIIACEGPERKERHEKLEKWVMRLELAGFGRVPLSYQGMLQASRLLVSYGYDGYRMKEENGCLVICWQDRPLFSVSAWR 430          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERL------QAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQA-MKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCW 1542
            L + L++CA+AVA  D   A   + ELR    V G   QR+ +  ++GL  RLA         +   +      SAE    +HL++EICP  +FGH   N +I EA + ES VH+ID  ++ G+    QW  LI +LA R G P  ++RITG+ +S            +G  L   A+S K+ FEF A   S   ++ +D  L  G+ L VN    LH +  ES    N    +L+ +  LSPK++ LVEQ+++ N   FL RF+EA++ Y A+F+S+D  LP+    R   EQ     EI NI++CEG                   AGF P PL     A +K L  N  + Y++ E  G L  GW  + ++A   W
Sbjct:  156 LKEVLVSCAKAVADNDILRAEWGISELRQMVSVSGEPIQRLGAYMLEGLVARLAA----SGSSIYKALRCKEPASAELLSYMHLLFEICPYFKFGHMSGNGAIAEAMKDESKVHIIDFQISQGV----QWITLIQALAARPGGP-PQIRITGIDDSTSAYARGGGPSIVGQRLSRFAESCKVPFEFHAATISGCEVQLEDLELRPGEALAVNFAFILHHMPDESVDTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAPFLSRFIEAMNYYLAVFESIDVTLPRDHKERINAEQHCLAREIVNIIACEGAERVERHELLGKWKSRFLMAGFTPHPLSSYVNATIKTLLQNYSDKYSLEEKDGALYLGWMDRALVAACAW 525          

Query:  427 ATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVY----EICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQ--PLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAV-----ESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLK--MIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCW 1542
            A ++ Q LI+CAE V+  D + A  LL  L +N+  FG S +R+   F   LS RL+           G ++ S   +A   EA H  Y    +I P I+F    AN +ILEA EG+ ++H++D  +     HG QW  L+ ++A R G   P   +RITG G     LQ  G+ L   AQS+ L F+F  +      +S     P    L+  + L VN +L LH L+K+    L   L  +  + PK++ + E++ +HN P FL RF+EAL +Y+A+FDSL+A LP     R  +E+ +FG EI +IVS EG                   +GF   PL    ++QA   L ++   EGY +         GW+++ + + S W
Sbjct:   33 AIQMRQLLISCAELVSQSDFSAARRLLSILSSNSSPFGDSTERLVHQFSAALSLRLSRYATPATSS--GAMSASANTAAADSEAFHSTYLSLNQITPFIRFSQLTANQAILEAIEGQRAIHILDFDIM----HGVQWPPLMQAIAERCGNLHPPPMIRITGTGEDLGILQRTGDRLLKFAQSLGLKFQFHPLLLRNDPTSVPLYLPSALQLLPDETLAVNCVLYLHRLLKDDSRDLRLFLHKIKAMEPKVVTIAEREANHNHPLFLQRFVEALDHYTAVFDSLEATLPPTSRERLAVERIWFGREIVDIVSAEGDNRRERHERFESWEVMLRSSGFSNVPLSPFALSQAKLLLRLHYPSEGYRLQIINDSFFLGWQNQALFSVSSW 412          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L+  L+ CAEAV+  +   A+ +L E+   +  FGTS QRVA+ F + +S RL        +G+   +  +   S +   A  +   I P ++F HF AN +I EAFE E  VH+IDL +  GL    QW  L   LA+R G P   +R+TG+G S E L+A G  L   A+ + L FEF  V     NL P+  N+   + + V+ +   H L  +  G+  + L  L +L+PK++ +VEQD SH G F LGRF+EA+H YSA+FDSL A   +   +R  +EQ     EI+N+++  GP+                 +GF+   L      QA   L +   +GYT+VED G L  GWK   ++  S W+
Sbjct:  292 LLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTSAQRVAAYFSEAMSARLVS----SCLGIYATLP-TVPHSQKLVSAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGL----QWPGLFHILASRPGGPPF-VRLTGLGTSMEALEATGKRLTDFAEKLGLPFEFFPVAEKVGNLDPERLNVSKREAVAVHWLQ--HSLY-DVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSF-LGRFVEAIHYYSALFDSLGASYGEESEQRHAVEQQLLSREIRNVLAVGGPS-RSGDVKFNNWREKLQQSGFRVVSLAGNAATQATLLLGMFPSDGYTLVEDNGTLKLGWKDLCLLTASAWR 648          

Query:  481 DKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAER------LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQA-MKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            D   A  L+ ELR    V G   QR+ +  ++GL  RLA         +   +      SA+    +H++YE+CP  +FG+  AN +I EA + E+ VH+ID      +  G QW  LI + + R G P H +RITG+ +S         L  +G  L   A+S+K+ FEF A + S   ++ ++     G+ L VN    LH +  ES    N    +L+ +  LSPK++ LVEQ+++ N   F  RF+E L+ Y+A+F+S+D  LP+   +R  +EQ     ++ NI++CEG                   AGF P PL  +  A +K L  N  + Y + E +G L  GW  + ++A+  WK
Sbjct:  129 DLLMAQWLMDELRQMVSVSGEPIQRLGAYMLEGLVARLAS----SGSSIYKALRCKEPASADLLSYMHILYEVCPYFKFGYMSANGAIAEAMKDENRVHIIDFQ----IGQGSQWITLIQAFSARPGGPPH-IRITGIDDSTSAYARGGGLNIVGQRLSRLAESVKVPFEFHAADMSGCEVQLENLGARPGEALAVNFAFMLHHMPDESVSTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAAFFPRFLETLNYYTAMFESIDVTLPREHKKRISVEQHCLARDVVNIIACEGVERVERHELLGKWRLRFAMAGFTPYPLSSLVNATIKRLLENYSDKYRLEEREGALYLGWMDRDLVASCAWK 484          

Query:  448 LIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG------NSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            LI CA+AVA  ++  A+ +L  +R ++  FG   QR+A  F   L  RLA     G        TK T+  A+  +A  L    CP  +  +  AN  I +  EG + +H+ID G+     +G+QW  LI  L+ R G P  +LRITG+         AER++  G  L  + +  K+ FE+ A+   +E +K +D   +D D  + +++L+L                 + +++P + I    + + N PFF  RF EAL ++ A+FD LDA +P+ D  R   E+  +G++I NI++CEG                   AG +  PL  +++ +    ++++  + + V  D G ++ GWK + I A SCWK
Sbjct:  149 LIQCAQAVAAYNQRAANDILKLIRQHSSPFGNGSQRLAHFFANSLEARLA---GTGLQMYTALATKRTSV-ADVIKAYQLYVSACPFKRMSNRYANRVIAKLAEGATRLHIIDFGVL----YGFQWPCLIQFLSLRPGGP-PKLRITGIDFPQPGFRPAERVEETGRRLANYCKRFKVPFEYKAIAQRWETIKVEDLE-IDRDGCLKDAVLEL-----------------IRRINPDIFIHGVLNGNFNTPFFFTRFREALFHFDALFDMLDASVPREDEGRMMFEREIYGKDIMNIIACEGSERIERPDIYKQWQARNERAGLRQLPLEQEILMKVRNIVKMDYHKDFVVEVDGGWMLHGWKGRVIYAISCWK 495          

Query:  427 ATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDE---ALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGV-----GNS-AERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXA-GFQPAPLKMIAQAMK-WLEI-------NTCEGYTVVEDK 1488
            A  +++ L+ CA  +A  +   A   L  LR +    G   +RVA  F + L  R++               + T F    +E   +   + + CP  +F H  AN +ILEA E    +H++D G+  G+    QW  L+ +LA R+     R+RI+G+     G S A  L A GN L+  A+ + LNFEF  + +  + L    F +   +VL VN +LQL+ L+ E+  ++N+ L+    L+PK+M L E +   N   F+ RF  AL  Y AIFDSL+  L +  + R ++E+   G  I  ++  E P                  + GF+  PL   A   + W E+       +  +G + V DK
Sbjct:  216 APPILKALLDCAR-LADSEPDRAVKSLIRLRESVSEHGDPTERVAFYFSEALYSRVSHQAE----------KRPTLFETSSEEFTLSYKALNDACPYSKFAHLTANQAILEATERARKIHIVDFGIVQGV----QWAALLQALATRSAGKPARIRISGIPAPALGKSPASSLFATGNRLRDFARLLDLNFEFEPILTPIQELNESTFRVDPDEVLAVNFMLQLYNLLDETPVSVNAALRLAKSLNPKIMTLGEYEACLNEVDFINRFKNALRYYRAIFDSLEPNLARDSSDRLQVERLLLGRRIAGVIGPEEPGTRRERMEDKEKWKFLVESCGFESVPLSHYASIDEAWKEVTNRFPPLSKTQGASAVHDK 572          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX-DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ +N S E  GLDL+LS+MAC P P  L T + N  +W++PF D+T   KR+++   SS    +  +N  SLYSG  S+C       L+S+P++HFRDHI  YT+RYLA EA+EEA +  M              D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG +  +      S +K+EAL LVYEICP I+FGHFVAN +ILEAFEGES VHV+DLGMTLGL HG+QWR LI+SLA RAG+   RLRITGVG   +R + IG++LK +A+ M +N EFSAVES+ ENL+P+D  + +G+VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL  N  C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSGEFNDENVS-ETSGLDLSLSAMACYPRPPYLPTFDSNAVSWILPFSDDTRDAKRMRR---SSSLVESIRSNNSSLYSGGSSICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPTMNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 516          

Query:    1 MASGLYVQAEFSGDNTSDEVIGLDLNLS-SMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            M S LY+Q+E   D T  E  GLDLN+  S+  +P   +       P  + +   DET SHKR+K       E    G    ++ S  GS+ A  L+SLPR+HFRD+I AYT RYLA+EAMEEA A LM             D  KLVQQLIACAEAVACRDK HAS LL ELRANA VFGTSFQRVASCFVQGLSDRL L+QPLGAVG++GP  K+ +F+AEKDEAL LVYEICPQIQFG+FVANA+ILEAFEGESS+HV+DLGMTLGLPHG QWRNL+  LANR  +    LRITGVGNSAERLQA+G++L  +A+S+ LNFEF  VESS E LK  DF L+DG+V+++NSILQLHC VKESRGALN+VLQ LH+LSPKL+ILVEQD+ HNGPFFLGR MEALH YSAIFDSLD MLPKYDT+R K+EQF++GEEIKNIVSCEGPA                 AGFQPA +KM  QA +WL +   CEGYTV EDKGCL+ GWKSKPIIA SCWK
Sbjct:    1 MPSALYMQSESFRDYTRYETTGLDLNIGYSIPHIPVSKN-----SRPTCFDL---DETRSHKRVKP---GGVESIGNGIGCYAVSSNGGSINANCLNSLPRLHFRDYIRAYTERYLAIEAMEEAAAGLMISKKNEIKEEDI-DGMKLVQQLIACAEAVACRDKTHASALLSELRANALVFGTSFQRVASCFVQGLSDRLTLLQPLGAVGVLGPAGKTISFTAEKDEALRLVYEICPQIQFGYFVANATILEAFEGESSIHVVDLGMTLGLPHGEQWRNLLHCLANRPDKKPRCLRITGVGNSAERLQALGDELDCYARSLGLNFEFLWVESSLEKLKSTDFKLLDGEVVIINSILQLHCAVKESRGALNTVLQILHELSPKLLILVEQDSGHNGPFFLGRVMEALHYYSAIFDSLDTMLPKYDTKRVKIEQFFYGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQPAQIKMAMQAKQWLGKAKVCEGYTVTEDKGCLILGWKSKPIIAASCWK 505          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ D T  E  GLDL+L++MAC P+P  L   E N  + ++PF DET   KR+KQ  S      + G+   SLYSG  S+C       L+++P++HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG++FQRVASCFVQGL DRL+L+QPLGAVG + P       +++K +EAL LVYEICP I+FGHFVAN SILEAFEGESSVHV+DLGMTLGLPHG+QWR LI SLA RAG+P  RLRITGVG   +R + IG++L+ +A+ M +N EFS V+SS ENL+P+D    + +VLVVNSILQLHC+VKESRGALNSVLQ + +LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLD MLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL +   C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSREFN-DETLSETSGLDLSLAAMACYPHPY-LPIFESNVVSRMLPFSDETRDVKRIKQSSSMVESIRSNGS---SLYSGGSSICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 515          

Query:   28 EFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGS---------MCARGLDSLPRIHFRDHISAYTRRYLAVEAMEE-ATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            + S D T +E   LD++LS+MA  PYP  L  LE N + +V+ F DET  HK+  ++  S  E   +   Y +  SGSGS              L+SLPR+HFRDHI  YT+RYLA EA+EE A A                D  +LVQ LIACAEAVACRDK+HAS LL ELR++A VFG+SFQRVASCF QGL+DRL+L+QPLG V L+ PI      +++K +EAL LVYEICP IQFGHFVAN+SILEAFEGES VHV+DLGMTLGLPHG+QWR LI SLANRAG+P  RLRIT VG    R Q IG++L  +A+ + +N EFS VES+ ENL+P D  + DG+VLVVNSILQLHC+VKESRGALNSVLQT+H LSPK++ LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLP+YDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL  N  C+GYTVVE+KGCLV GWKSKPI+A SCWK
Sbjct:    9 DLSHDETINETSSLDISLSAMAYYPYPY-LPILENNESIFVLDFSDETREHKKRIKRALSFAESTGSDGIYNTGGSGSGSGSNDTISRSCSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEGAEAMANSEEGENHGEGGNTDGMRLVQLLIACAEAVACRDKSHASALLSELRSSALVFGSSFQRVASCFFQGLADRLSLVQPLGTVSLVTPIMNIMDIASDKKEEALSLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGHQWRQLIQSLANRAGKPPCRLRITAVGLCVGRFQTIGDELVEYAKDVGINLEFSVVESTLENLQPDDIKVFDGEVLVVNSILQLHCVVKESRGALNSVLQTIHALSPKILALVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPRYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHEKVDQWRRRMSRAGFQAAPVKMMAQAKQWLGKNKVCDGYTVVEEKGCLVLGWKSKPIVAASCWK 525          

Query:   25 AEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAA--WVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSG------------SGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++   +  SDEV GLD +LS+ A   Y  S   + +N +A  W   + DE  +HKRLK+  S +    + G+N  SLYSG            + S     L+SLPR+HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK HAS+LL ELRANA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG I P      TA+  +K+EAL LVYEICP I+FGHFVANASILEAFEGE+  HV+DLGMTLGL HG QWR LI SLANRAG+P  RLRITGVG   +R + IG +L+ +AQ + +N EFSAVES+ ENL+P+D    DG+ LVVNSILQLHC+VKESRGALNSVLQ +++LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSL+AMLPKYDTRRAK+EQFYFGEEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL ++  CEGY ++E+KGCLV GWKSKPI+A SCWK
Sbjct:    3 SDLLSEERSDEVSGLDTSLSAQAY--YSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIA---ESIGSN-SSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWE-KKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLEFSAVESNLENLRPEDIKREDGEALVVNSILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWK 518          

Query:   40 DNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX--DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            D  S++ IGL L LS + C PY   L  + +N AA     I +    KRLK+  S     + + T+  S  S + S     L +LPR+ FRDHI  YTRRYLA EA+EEA A ++               D  +LVQ LIACAEAVACRDK+HAS LL ELRANA VFG+SFQRVASCFVQGL+DRLA +QPLGAVG   P       A S EK+EA  LVYEICP IQFGHFVAN+SILEAFEGES VHV+DLGMTLGLP G QWR LI+SLANRAGQP  RLRIT VG   E+ Q+IG++LK +A++  +N EFS VES+ ENL+ +D  +++ +VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDT+RAK+EQFYF EEIKNIVSCEGPA                 AGFQ AP+KMI QA KWL+ N  CEGYTVVE+KGCLV GWKSKPIIAT+CWK
Sbjct:   15 DQRSNQAIGLQLGLSIVDCYPY---LPMMSDNSAA--SSMILQPRDQKRLKRTISVG---DGSPTSTLSRSSSTSS-----LSNLPRLQFRDHIWTYTRRYLAAEAVEEAAAAMIKSEDGCDGDQQDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLADRLASVQPLGAVGSFAPSMNIMDIAGSREKEEAFRLVYEICPHIQFGHFVANSSILEAFEGESLVHVVDLGMTLGLPRGQQWRRLIESLANRAGQPPRRLRITAVGLCVEKFQSIGDELKDYAKTYGINLEFSVVESNLENLQTKDIKVLENEVLVVNSILQLHCVVKESRGALNSVLQIIHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTKRAKIEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMINQAQKWLKNNKVCEGYTVVEEKGCLVLGWKSKPIIATTCWK 508          

Query:  103 YPSSLSTLEENPAA-WVI-PFIDETSS----HKRLKQQ-------------HSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATA-TLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKST-----AFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            YP+ L  LE +  + W++ PF D  +     HK+LK+              HS+S+ FNN  +N  S+            +S+PR+HFRDHI  Y +RY A EA+EEA                   D  +LVQ LIACAEAVACRDK+HAS LL EL++NA VFG+SFQRVASCFVQGL++RL LIQP+G     G  TKS      A S E +EA  LVYE CP IQFGHFVAN+ ILEAFEGES +HV+DLGM+LGLPHG+QWR LI SLA+R+   + RLRIT +G    R+Q IG +L ++A+++ ++ EFS VE + ENLKP+D  + + +VLVVNSILQLHC+VKESRGALN+VLQ +H LSPK++++ EQD+ HNGPFFLGRFME+LH YSAIFDSLDAMLPKYDT+RAKMEQFYF EEIKNIVSCEGP                  AGFQ +P+KM+ QA +WL + N C+GYTVVE+KGCLV GWKSKPI+A SCWK
Sbjct:   29 YPN-LPILENSATSTWILNPFSDHETETIRDHKKLKRSTVTIPIWFANFSSHSNSF-FNNINSNNNSV------------NSIPRLHFRDHIRTYKQRYFASEAVEEAAEDNFNYNNCEAEEDGSCADGMRLVQLLIACAEAVACRDKSHASVLLSELKSNALVFGSSFQRVASCFVQGLTERLTLIQPIGN-NSAGSDTKSMMNIMDAASEEMEEAFKLVYENCPHIQFGHFVANSIILEAFEGESFLHVVDLGMSLGLPHGHQWRGLIQSLADRSSHRVRRLRITAIGLCIARIQVIGEELSIYAKNLGIHLEFSIVEKNLENLKPKDIKVNEKEVLVVNSILQLHCVVKESRGALNAVLQMIHGLSPKVLVMAEQDSGHNGPFFLGRFMESLHYYSAIFDSLDAMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHEKVDQWRRRMSRAGFQGSPIKMVVQAKQWLVKNNVCDGYTVVEEKGCLVLGWKSKPIVAVSCWK 520          

Query:   28 EFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVI--PFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVG-LIGPITK-STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRA-GQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            E  G+N     +  D+  +++    Y      + EN ++ ++  PF D T      + + +  +   N+ + +    + S S      +S+P++HFRDHI  YT+RYLA E +EEA+                    +LVQ LIACAEAVACRDK+HAS LL EL+ANA VFG+SFQRVASCFVQGL++RL LIQP+G+ G ++ P      A S E +EA  LVYE+CP IQFGH++AN+++LEAFEGES VHV+DLGM+LGL HG+QWR LI SLANRA G+ + RLRITGVG    RLQ IG +L ++A ++ +N EFS V  + ENLKP+D  + + +VLVVNSILQLHC+VKESRGALNSVLQ +H L PK++++VEQD+SHNGPFFLGRFME+LH YS+IFDSLD MLPKYDT+RAKMEQFYF EEIKNIVSCEGP                  AGFQ AP+KM+AQ+ +WL  N  CEGYTVVE+KGCLVFGWKS+PI+A SCWK
Sbjct:   11 EIDGENLP---LAFDIWATNLWAYGYYPHQPAISENSSSKLVDFPFCDGTIIRDNKRVKRTVCFPIYNSVSCHSFFNTNSSSR-----NSIPKLHFRDHIRTYTQRYLAAEPVEEASEDTNM---------------RLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLTERLNLIQPIGSAGPMMAPAMNIMDAASDEMEEAYRLVYELCPHIQFGHYLANSTVLEAFEGESFVHVVDLGMSLGLRHGHQWRALIQSLANRASGERVRRLRITGVGLCV-RLQTIGEELSVYANNLGINLEFSVVNKNLENLKPEDIEVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQSKQWLLKNKVCEGYTVVEEKGCLVFGWKSRPIVAVSCWK 498          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKST--AFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAG-QPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            D  +LVQ LIACAEAVACRDK+HAS LL EL+ANA VFG+SFQRVASCFVQGL +RL LIQP+G  G + P   +     S E +EA  LVYE+CP IQFGH++AN++ILEAFEGES VHV+DLGM+LGL HG+QWR LI +LA R G + + RLRITGVG   ERLQ IG +L ++A ++ +N EFS VE + ENLKP+D  + + +VLVVNSILQLHC+VKESRGALNSVLQ +H L PK++++VEQD+SHNGPFFLGRFME+LH YS+IFDSLD MLPKYDT+RAKMEQFYF EEIKNIVSCEGP                  AGFQ AP+KM+AQA +WL  N  CEGYTVVE+KGCLV GWKS+PI+A SCWK
Sbjct:   99 DGVRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLIERLNLIQPIGPAGPMMPSMMNIMDVASDEMEEAFRLVYELCPHIQFGHYLANSTILEAFEGESFVHVVDLGMSLGLRHGHQWRGLIQNLAGRVGGERVRRLRITGVG-LCERLQTIGEELSVYANNLGVNLEFSVVEKNLENLKPEDIKVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQAKQWLLKNKVCEGYTVVEEKGCLVLGWKSRPIVAVSCWK 475          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQP--LGAVGLIGPITKS-TAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            D  +LVQ L+ACAEAVACRD+A A+ LL EL+A A V GT+FQRVASCFVQGL+DRLAL  P  LG   +   I  S T     + EAL L YE+CP ++F HFVANASILEAFEGES+VHV+DLGMTLGL   +QWR L+D LA RAG    R+R+T VG  AE ++A+G +L+ +A+ + L  EF A++ S E+L   D  +   + + ++SIL+LHC+VKESRGALNSVLQT+ +LSPK  +LVEQD  HNGPFFLGRFMEALH Y+A+FD+LDA LP+YD RRA++EQF+FG EI+N+V CEG A                 AGFQ  P++M A+A +WLE N    GYTV E+KGCLV GWK KP+IA SCWK
Sbjct:  159 DGMRLVQLLVACAEAVACRDRAQAAALLRELQAGAPVHGTAFQRVASCFVQGLADRLALAHPPALGPASMAFCIPPSCTGRDGARGEALALAYELCPYLRFAHFVANASILEAFEGESNVHVLDLGMTLGLDRAHQWRGLLDGLAARAGAKPARVRVTAVGAPAETMRAVGRELEAYAEGLGLCLEFRAIDRSLESLHMDDLGIAADEAVAISSILELHCVVKESRGALNSVLQTIRKLSPKAFVLVEQDAGHNGPFFLGRFMEALHYYAAVFDALDAALPRYDARRARVEQFHFGAEIRNVVGCEGAARVERHERADQWRRRMSRAGFQSVPIRMAARAREWLEENAGGGGYTVAEEKGCLVLGWKGKPVIAASCWK 536          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAM-LPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+ ++   A     + ++VA+ F +GL+ R+  + P           K    S      +H  YE CP ++F HF AN +ILEAFEG+  VHVID  M  G+    QW  L+ +LA R G P    R+TG+G    ++ + L  +G  L   A+++ + FE+   V +S  +L      L DG+ + VNS+ +LH L+    G +  VL  +  + P ++ +VEQ+ +HNGP FL RF E+LH YS +FDSL+   +   +T+   M + Y G++I N+V+CEGP                  AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:  213 RLVHTLMACAEAVQQENLKLAEALVKQIGFLAVSQAGAMRKVATYFAEGLARRIYRLYP----------DKPLDSSFSDILQMHF-YETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMKQGM----QWPALMQALALRPGGP-PSFRLTGIGPPSTDNTDHLHEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRDGESVAVNSVFELHSLLARP-GGIERVLSAVKDMKPDIVTIVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGCGVSPVNTQDKLMSEVYLGQQICNVVACEGPERVERHETLAQWRARLGSAGFDPVNLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 575          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVE-SSFENLKPQDFNLVDG-DVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIA--QAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+  +   A     + ++VA+ F +GL+ R+  I P   V L          S+  D      YE CP ++F HF AN +ILE F     VHVIDLG+     HG QW  LI +LA R   P    R+TG+G S   +Q +G  L   A ++ +NFEF ++  ++  +LKP+  ++  G + + VNS+ +LH L+    G+++  L T+  + P +M +VEQ+ +HNG  FL RF E+LH YS++FDSL+   P  D     M + + G +I N+V+CEG                    GF+P  +   A  QA   L +    +GY V E++GCL+ GW+++P+IATS W+
Sbjct:  151 RLVHALLACAEAVQQNNLKLADALVKHVGLLASSQAGAMRKVATYFAEGLARRIYRIYPRDDVAL----------SSFSDTLQIHFYESCPYLKFAHFTANQAILEVFATAEKVHVIDLGLN----HGLQWPALIQALALRPNGPPD-FRLTGIGYSLTDIQEVGWKLGQLASTIGVNFEFKSIALNNLSDLKPEMLDIRPGLESVAVNSVFELHRLLAHP-GSIDKFLSTIKSIRPDIMTVVEQEANHNGTVFLDRFTESLHYYSSLFDSLEGP-PSQD---RVMSELFLGRQILNLVACEGEDRVERHETLNQWRNRFGLGGFKPVSIGSNAYKQASMLLALYAGADGYNVEENEGCLLLGWQTRPLIATSAWR 506          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA--------VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEA+   D + A  L+ ++   A     + ++VA+ F + L+ R+  + P             T       + L +  YE CP ++F HF AN +ILEAFEG+  VHVID  M  GL    QW  L+ +LA R G P    R+TG+G    ++++ L  +G  L   A+++ + FE+          +++S   L+P +   V      VNS+ +LH L+  + G +  VL  + Q+ P +  +VEQ++SHNGP FL RF E+LH YS +FDSL+ +    D     M + Y G++I N+V+CEGP                  +GF PA L      QA   L + N  EGY V E+ GCL+ GW ++P+I TS WK
Sbjct:  210 NGVRLVHALMACAEAIQNNDLSIAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYRLSP-----------PQTQIDHSLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGP-PVFRLTGIGPPAADNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSEIEAV-----AVNSVFELHKLLGRT-GGIEKVLGVVKQIKPVIFTVVEQESSHNGPVFLDRFTESLHYYSTLFDSLEGVPSSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWANRFGSSGFAPAHLGSNAFKQASMLLALFNGGEGYRVEENNGCLMLGWHTRPLITTSAWK 574          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNL--VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEA+   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P           ++       D      YE CP ++F HF AN +ILEAFEG+  VHVID  M  GL    QW  L+ +LA R G P    R+TG+G    ++++ L  +G  L   A+++ + FE+   V +S  +L      L   D + + VNS+ +LH L+    G +  VL  + Q+ P +  +VEQ+++HNGP FL RF E+LH YS +FDSL+ +    D     M + Y G++I N+V+CEGP                  +G  PA L      QA   L + N+ +GY V E  GCL+ GW ++P+I TS WK
Sbjct:  217 NGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSP----------PQNQIDHCLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGP-PTFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRP-GGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWK 581          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYE----ICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L+  L+ CAEAV   +   A   L E+   A  FGTS QRVA+ F + +S RL        +GL  P+   +  +A     +   ++    I P ++F HF AN +I EAFE E  VH+IDL +  GL    QW  L   LA+R G P  R+R+TG+G S E L+A G  L   A ++ L FEF AV     N+ P+   +   + + V+    LH  + +  G+ ++ L  + +L+PK++ +VEQD SH+G F L RF+EA+H YSA+FDSLDA   +    R  +EQ     EI+N+++  GPA                 +GF+ A L     AQA   L +   +GYT+VE+ G L  GWK   ++  S W+
Sbjct:  299 LLTLLLQCAEAVNADNLDDAHQTLLEIAELATPFGTSTQRVAAYFAEAMSARLVS----SCLGLYAPLPPGSPAAARLHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGL----QWPGLFHILASRPGGP-PRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCAVAEKAGNVDPEKLGVTRREAVAVH---WLHHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSF-LARFVEAIHYYSALFDSLDASYGEDSPERHVVEQQLLSREIRNVLAVGGPA-RTGDVKFGSWREKLAQSGFRAASLAGSAAAQASLLLGMFPSDGYTLVEENGALKLGWKDLCLLTASAWR 660          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNL--VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEAV   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P             T       + L +  YE CP ++F HF AN +ILEAFEG+  VHVID  M  GL    QW  L+ +LA R G P    R+TG+G    ++++ L  +G  L   A+++ + FE+   V +S  +L      L   + + + VNS+ +LH L+  + G +  V   + Q+ P +  +VEQ+++HNGP FL RF E+LH YS +FDSL+      D     M + Y G++I N+V+CEGP                  +GF PA L      QA   L + N  EGY V E+ GCL+  W ++P+I TS WK
Sbjct:  204 NGVRLVHALMACAEAVQSSNLTLAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYRLSP-----------PQTQIDHSLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGP-PSFRLTGIGPPAADNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSETEAVAVNSVFELHKLLGRT-GGIEKVFGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGAPSSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWSNRFGSSGFAPAHLGSNAFKQASTLLALFNGGEGYRVEENNGCLMLSWHTRPLITTSAWK 568          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSA----ERLQAIGNDLKLHAQSMKLNFEFSA--------VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEAV   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P  +     PI  S + + +    +H  YE CP ++F HF AN +ILEAF+G+  VHVID  M+ GL    QW  L+ +LA R G P    R+TG+G  A    + L  +G  L   A+++ + FE+          +++S   L+P +   V      VNS+ +LH L+    GA++ VL  ++Q+ P++  +VEQ+++HN P FL RF E+LH YS +FDSL+ +    D     M + Y G++I N+V+C+GP                  AGF  A +      QA   L + N  EGY V E  GCL+ GW ++P+IATS WK
Sbjct:  165 NGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQS-----PIDHSLSDTLQ----MHF-YETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGL----QWPALMQALALRPGGP-PVFRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEIESV-----AVNSVFELHKLLGRP-GAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQD---KVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWK 529          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSAVES-SFENLKPQDFNL-VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLD--AMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIA--QAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEA+   +   A  L+  +   A     +  +VA+ F Q L+ R+                   A +   +E L +  YE CP ++F HF AN +ILEA      VHVIDLG+  G+    QW  L+ +LA R G P    R+TG+G     +++ LQ +G  L   AQ+M + FEF  + + S  +L+P+ F    + + LVVNS+ +LH L+  S G++  +L T+  + P ++ +VEQ+ +HNG  FL RF EALH YS++FDSL+    LP  D     M + Y G +I N+V+ EG                   AGF P  L   A  QA   L +  T +GY V E+ GCL+ GW+++P+I TS WK
Sbjct:  179 RLVHALVACAEAIHQENLNLADALVKRVGTLAGSQAGAMGKVATYFAQALARRIYR-------DYTAETDVCAAVNPSFEEVLEMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGM----QWPALMQALALRPGGP-PSFRLTGIGPPQTENSDSLQQLGWKLAQFAQNMGVEFEFKGLAAESLSDLEPEMFETRPESETLVVNSVFELHRLLARS-GSIEKLLNTVKAIKPSIVTVVEQEANHNGIVFLDRFNEALHYYSSLFDSLEDSYSLPSQD---RVMSEVYLGRQILNVVAAEGSDRVERHETAAQWRIRMKSAGFDPIHLGSSAFKQASMLLSLYATGDGYRVEENDGCLMIGWQTRPLITTSAWK 545          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYE----ICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L+  L+ CAE+V   +   A   L E+   A  FGTS QRVA+ F + +S RL        +GL  P+   +  +A     +   ++    I P ++F HF AN +I EAFE E  VH+IDL +  GL    QW  L   LA+R G P  R+R+TG+G S E L+A G  L   A ++ L FEF  V     NL P+   +   + + V+ +   H L  +  G+ ++ L  + +L+PK++ +VEQD SH+G F L RF+EA+H YSA+FDSLDA   +    R  +EQ     EI+N+++  GPA                 +GF+ + L     AQA+  L +   +GYT++E+ G L  GWK   ++  S W+
Sbjct:  283 LLTLLLQCAESVNADNLDEAHRALLEIAELATPFGTSTQRVAAYFAEAMSARLVS----SCLGLYAPLPNPSPAAARLHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGL----QWPGLFHILASRPGGP-PRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCPVADKAGNLDPEKLGVTRREAVAVHWLR--HSLY-DVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSF-LARFVEAIHYYSALFDSLDASYSEDSPERHVVEQQLLSREIRNVLAVGGPA-RTGDVKFGSWREKLAQSGFRVSSLAGSAAAQAVLLLGMFPSDGYTLIEENGALKLGWKDLCLLTASAWR 644          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDV--LVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ CAEAV   +   A  L+  +   A     + ++VA+ F + L+ R+  + P        P+ +S     +    +H  YE CP ++F HF AN +ILEAFEG+  VHVID  M  G+    QW  LI +LA R   P    R+TG+G    ++++ LQ +G  L   A+++ + FE+   V +S  +L      L   +V  +VVNS+ +LH L+    GA+  VL  + Q+ P+++ +VEQ+ +HNGP F+ RF E+LH YS +FDSL+      D     M + Y G++I N+V+CEG                   AGF P  L      QA   L +  + EGY V E++G L+ GW ++P+IATS WK
Sbjct:  210 QLVHALMVCAEAVQQNNLNLAEALVKRIDYLAVSQAGAMRKVATFFAEALARRIYRLCPEN------PLDRSVLDMLQ----MHF-YESCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGI----QWPALIQALALRPSGP-PTFRLTGIGPPAPDNSDYLQDVGWKLVKFAETLHVEFEYRGFVANSLADLDASMLELRPSEVESVVVNSVFELHQLLARP-GAIEKVLSVVKQMKPEIVTVVEQEANHNGPVFVERFTESLHYYSTLFDSLECSPNSQD---KMMSEMYLGKQICNVVACEGADRVERHETLTQWRTRLSSAGFDPIHLGSNAFKQASILLALFGSGEGYRVEENEGSLMLGWHTRPLIATSAWK 570          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVE-SSFENLKPQDFNLVDG-DVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIA--QAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+  +   A     + ++VA+ F +GL+ R+  I P   V L          S+  D      YE CP ++F HF AN +ILE F     VHVIDLG+     HG QW  LI +LA R   P    R+TG+G S   +Q +G  L   A ++ +NFEF ++  ++  +LKP+  ++  G + + VNS+ +LH L+    G+++  L T+  + P +M +VEQ+ +HNG  FL RF E+LH YS++FDSL+   P  D     M + + G +I N+V+CEG                    GF+P  +   A  QA   L +    +GY V E++GCL+ GW+++P+IATS W+
Sbjct:  151 RLVHALLACAEAVQQNNLKLADALVKHVGLLASSQAGAMRKVATYFAEGLARRIYRIYPRDDVAL----------SSFSDTLQIHFYESCPYLKFAHFTANQAILEVFATAEKVHVIDLGLN----HGLQWPALIQALALRPNGPPD-FRLTGIGYSLTDIQEVGWKLGQLASTIGVNFEFKSIALNNLSDLKPEMLDIRPGLESVAVNSVFELHRLLAHP-GSIDKFLSTIKSIRPDIMTVVEQEANHNGTVFLDRFTESLHYYSSLFDSLEGP-PSQD---RVMSELFLGRQILNLVACEGEDRVERHETLNQWRNRFGLGGFKPVSIGSNAYKQASMLLALYAGADGYNVEENEGCLLLGWQTRPLIATSAWR 506          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNL--VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEA+   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P           ++       D      YE CP ++F HF AN +ILEAFEG+  VHVID  M  GL    QW  L+ +LA R G P    R+TG+G    ++++ L  +G  L   A+++ + FE+   V +S  +L      L   D + + VNS+ +LH L+    G +  VL  + Q+ P +  +VEQ+++HNGP FL RF E+LH YS +FDSL+ +    D     M + Y G++I N+V+CEGP                  +G  PA L      QA   L + N+ +GY V E  GCL+ GW ++P+I TS WK
Sbjct:  217 NGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSP----------PQNQIDHCLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGP-PTFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRP-GGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWK 581          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSA----ERLQAIGNDLKLHAQSMKLNFEFSA--------VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEAV   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P  +     PI  S + + +    +H  YE CP ++F HF AN +ILEAF+G+  VHVID  M+ GL    QW  L+ +LA R G P    R+TG+G  A    + L  +G  L   A+++ + FE+          +++S   L+P +   V      VNS+ +LH L+    GA++ VL  ++Q+ P++  +VEQ+++HN P FL RF E+LH YS +FDSL+ +    D     M + Y G++I N+V+C+GP                  AGF  A +      QA   L + N  EGY V E  GCL+ GW ++P+IATS WK
Sbjct:  165 NGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQS-----PIDHSLSDTLQ----MHF-YETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGL----QWPALMQALALRPGGP-PVFRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEIESV-----AVNSVFELHKLLGRP-GAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQD---KVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWK 529          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSAVES-SFENLKPQDFNL-VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLD--AMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIA--QAMKWLEI-NTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEA+   +   A  L+  +   A     +  +VA+ F Q L+ R+                   A +   +E L +  YE CP ++F HF AN +ILEA      VHVIDLG+  G+    QW  L+ +LA R G P    R+TG+G     +++ LQ +G  L   AQ+M + FEF  + + S  +L+P+ F    + + LVVNS+ +LH L+  S G++  +L T+  + P ++ +VEQ+ +HNG  FL RF EALH YS++FDSL+    LP  D     M + Y G +I N+V+ EG                   AGF P  L   A  QA   L +  T +GY V E+ GCL+ GW+++P+I TS WK
Sbjct:  179 RLVHALVACAEAIHQENLNLADALVKRVGTLAGSQAGAMGKVATYFAQALARRIYR-------DYTAETDVCAAVNPSFEEVLEMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGM----QWPALMQALALRPGGP-PSFRLTGIGPPQTENSDSLQQLGWKLAQFAQNMGVEFEFKGLAAESLSDLEPEMFETRPESETLVVNSVFELHRLLARS-GSIEKLLNTVKAIKPSIVTVVEQEANHNGIVFLDRFNEALHYYSSLFDSLEDSYSLPSQD---RVMSEVYLGRQILNVVAAEGSDRVERHETAAQWRIRMKSAGFDPIHLGSSAFKQASMLLSLYATGDGYRVEENDGCLMIGWQTRPLITTSAWK 545          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAER--LQAIGNDLKLHAQSMKLNFEFSAVESS-FENLKPQDFNL-VDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLD--AMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIA--QAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LVQ L+ACAEAV   + + A  L+  +   A     +  +VA+ F + L+ R+  I P  A           A     +E L +  Y+ CP ++F HF AN +ILEA      VHVIDLG+  G+    QW  L+ +LA R G P    R+TGVGN + R  +Q +G  L   AQ++ + F+F+ + +    +L+P  F    + + LVVNS+ +LH ++ +  G++  +L T+  + P L+ +VEQ+ +HNG  FL RF EALH YS++FDSL+   ++P  D     M + Y G +I N+V+ EG                   AGF P  L   A  QA   L ++   +GY V E+ G L+  W++KP+IA S WK
Sbjct:  156 RLVQALVACAEAVQLENLSLADALVKRVGLLAASQAGAMGKVATYFAEALARRIYRIHPSAA-----------AIDPSFEEILQMNFYDSCPYLKFAHFTANQAILEAVTTSRVVHVIDLGLNQGM----QWPALMQALALRPGGP-PSFRLTGVGNPSNREGIQELGWKLAQLAQAIGVEFKFNGLTTERLSDLEPDMFETRTESETLVVNSVFELHPVLSQP-GSIEKLLATVKAVKPGLVTVVEQEANHNGDVFLDRFNEALHYYSSLFDSLEDGVVIPSQD---RVMSEVYLGRQILNLVATEGSDRIERHETLAQWRKRMGSAGFDPVNLGSDAFKQASLLLALSGGGDGYRVEENDGSLMLAWQTKPLIAASAWK 516          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCW 1542
            L+  L+ CAEAV+  +   A+ LL E+   +  +GTS QRVA+ F + +S RL L   LG    +         S +   A  +   I P ++F HF AN +I EAFE E SVH+IDL +  GL    QW  L   LA+R G P H +R+TG+G S E LQA G  L   A  + L FEF  +     NL  +  N+   + + V+ +   H L  +  G+    L  L +L+PK++ +VEQD SH G F LGRF+EA+H YSA+FDSL A   +    R  +EQ    +EI+N+++  GP+                  GF+   L      QA   L +   +GYT+V+D G L  GWK   ++  S W
Sbjct:  290 LLTLLLQCAEAVSADNLEEANKLLLEISQLSTPYGTSAQRVAAYFSEAMSARL-LNSCLGIYAALPSRWMPQTHSLKMVSAFQVFNGISPLVKFSHFTANQAIQEAFEKEDSVHIIDLDIMQGL----QWPGLFHILASRPGGPPH-VRLTGLGTSMEALQATGKRLSDFADKLGLPFEFCPLAEKVGNLDTERLNVRKREAVAVHWLQ--HSLY-DVTGSDAHTLWLLQRLAPKVVTVVEQDLSHAGSF-LGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSKEIRNVLAVGGPS-RSGEVKFESWREKMQQCGFKGISLAGNAATQATLLLGMFPSDGYTLVDDNGTLKLGWKDLSLLTASAW 649          

Query:  448 LIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTA-FSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAER------LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLK-MIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L++CA+A++  D   A +++ +LR    V G   QR+ +  ++GL  +LA         +   + +     S E    +H++YE+CP  +FG+  AN +I EA + E+ VH+ID      +  G QW  LI + A R G P  R+RITG+ +          L  +GN L   A+   + FEF++V  S   +KP++  +  G+ L VN    LH +  ES    N    +L+ +  LSPK++ LVEQ+++ N   F  RFME ++ Y+A+F+S+D  LP+   +R  +EQ     ++ NI++CEG                   AGF P PL  ++   +K L  N  + Y + E  G L  GW  + ++A+  WK
Sbjct:  123 LVSCAKAMSENDLMMAHSMMEKLRQMVSVSGEPIQRLGAYLLEGLVAQLAS----SGSSIYKALNRCPEPASTELLSYMHILYEVCPYFKFGYMSANGAIAEAMKEENRVHIIDFQ----IGQGSQWVTLIQAFAARPGGP-PRIRITGIDDMTSAYARGGGLSIVGNRLAKLAKQFNVPFEFNSVSVSVSEVKPKNLGVRPGEALAVNFAFVLHHMPDESVSTENHRDRLLRMVKSLSPKVVTLVEQESNTNTAAFFPRFMETMNYYAAMFESIDVTLPRDHKQRINVEQHCLARDVVNIIACEGADRVERHELLGKWRSRFGMAGFTPYPLSPLVNSTIKSLLRNYSDKYRLEERDGALYLGWMHRDLVASCAWK 490          

Query:  448 LIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTA-FSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAER------LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLK-MIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L++CA+A++  D   A +++ +LR    V G   QR+ +  ++GL  +LA         +   + +     S E    +H++YE+CP  +FG+  AN +I EA + E+ VH+ID      +  G QW  LI + A R G P  R+RITG+ +          L  +GN L   A+   + FEF++V  S   +KP++  +  G+ L VN    LH +  ES    N    +L+ +  LSPK++ LVEQ+++ N   F  RFME ++ Y+A+F+S+D  LP+   +R  +EQ     ++ NI++CEG                   AGF P PL  ++   +K L  N  + Y + E  G L  GW  + ++A+  WK
Sbjct:  123 LVSCAKAMSENDLMMAHSMMEKLRQMVSVSGEPIQRLGAYLLEGLVAQLAS----SGSSIYKALNRCPEPASTELLSYMHILYEVCPYFKFGYMSANGAIAEAMKEENRVHIIDFQ----IGQGSQWVTLIQAFAARPGGP-PRIRITGIDDMTSAYARGGGLSIVGNRLAKLAKQFNVPFEFNSVSVSVSEVKPKNLGVRPGEALAVNFAFVLHHMPDESVSTENHRDRLLRMVKSLSPKVVTLVEQESNTNTAAFFPRFMETMNYYAAMFESIDVTLPRDHKQRINVEQHCLARDVVNIIACEGADRVERHELLGKWRSRFGMAGFTPYPLSPLVNSTIKSLLRNYSDKYRLEERDGALYLGWMHRDLVASCAWK 490          

Query:  427 ATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENL-KPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSH-NGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLK--MIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            A KL+  L+ CAE VA      ASTLL E+      FG+S +RV + F Q L  R+      GA   +     +   S +   AL     + P I+F HF AN +I +A +GE SVH+IDL +  GL    QW  L   LA+R  + L  +RITG G+S++ L + G  L   A S+ L FEF  +E    NL  P       G+ +VV+     H L   +   L + L+ L +L P L+ +VEQ+ S+ +G  FLGRF+EALH YSA+FD+L   L +    R  +EQ   G EI+NIV+  G                    GF+P  L+     QA   L +    GYT+VE+ G L  GWK   ++  S WK
Sbjct:   37 AIKLLSLLLQCAEYVATDHLREASTLLSEISEICSPFGSSPERVVAYFAQALQTRVISSYLSGACSPLSEKPLTVVQSQKIFSALQTYNSVSPLIKFSHFTANQAIFQALDGEDSVHIIDLDVMQGL----QWPALFHILASRP-RKLRSIRITGFGSSSDLLASTGRRLADFASSLNLPFEFHPIEGIIGNLIDPSQLATRQGEAVVVH--WMQHRLYDVTGNNLET-LEILRRLKPNLITVVEQELSYDDGGSFLGRFVEALHYYSALFDALGDGLGEESGERFTVEQIVLGTEIRNIVAHGG-----GRRKRMKWKEELSRVGFRPVSLRGNPATQAGLLLGMLPWNGYTLVEENGTLRLGWKDLSLLTASAWK 400          

Query:  442 QQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGN--SAER----LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQ---LSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            Q LI+CA A++      A +++ ELR    + G   QR+A+  V+GL+ R+A         +   +      S E+  A+ +++E+CP  +FG   AN +ILEA +GE  VH+ID  +      G Q+  LI S+A   G+   RLR+TG+ +  S +R    L+ IG  L+  A+   ++F+F A+ S    + P       G+ L+VN   QLH +  ES   +N   + LH    L+PKL+ +VEQD + N   F  RF+EA   YSA+F+SLD  LP+    R  +E+     +I NIV+CEG                   AGF P P+  K+       ++   C  Y + E+ G L F W+ K +I  S W+
Sbjct:  224 QILISCARALSEGKLEEALSMVNELRQIVSIQGDPSQRIAAYMVEGLAARMAASGKF----IYRALKCKEPPSDERLAAMQVLFEVCPCFKFGFLAANGAILEAIKGEEEVHIIDFDIN----QGNQYMTLIRSIAELPGKR-PRLRLTGIDDPESVQRSIGGLRIIGLRLEQLAEDNGVSFKFKAMPSKTSIVSPSTLGCKPGETLIVNFAFQLHHMPDESVTTVNQRDELLHMVKSLNPKLVTVVEQDVNTNTSPFFPRFIEAYEYYSAVFESLDMTLPRESQERMNVERQCLARDIVNIVACEGEERIERYEAAGKWRARMMMAGFNPKPMSAKVTNNIQNLIKQQYCNKYKLKEEMGELHFCWEEKSLIVASAWR 593          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX-DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ +N S E  GLDL+LS+MAC P P  L T + N  +W++PF D+T   KR+++   SS    +  +N  SLYSG  S+C       L+S+P++HFRDHI  YT+RYLA EA+EEA +  M              D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG +  +      S +K+EAL LVYEICP I+FGHFVAN +ILEAFEGES VHV+DLGMTLGL HG+QWR LI+SLA RAG+   RLRITGVG   +R + IG++LK +A+ M +N EFSAVES+ ENL+P+D  + +G+VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL  N  C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSGEFNDENVS-ETSGLDLSLSAMACYPRPPYLPTFDSNAVSWILPFSDDTRDAKRMRR---SSSLVESIRSNNSSLYSGGSSICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPTMNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 516          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ D T  E  GLDL+L++MAC P+P  L   E N  + ++PF DET   KR+KQ  S      + G+   SLYSG  S+C       L+++P++HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG++FQRVASCFVQGL DRL+L+QPLGAVG + P       +++K +EAL LVYEICP I+FGHFVAN SILEAFEGESSVHV+DLGMTLGLPHG+QWR LI SLA RAG+P  RLRITGVG   +R + IG++L+ +A+ M +N EFS V+SS ENL+P+D    + +VLVVNSILQLHC+VKESRGALNSVLQ + +LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLD MLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL +   C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSREFN-DETLSETSGLDLSLAAMACYPHPY-LPIFESNVVSRMLPFSDETRDVKRIKQSSSMVESIRSNGS---SLYSGGSSICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 515          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLI---GPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGV--GNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENL--KPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            LV  L+ACAEA++CRD   A T+L ++  +   +G S QRV+ CF  GL  RL+ +  + A G     G + +S    AEK EA  L+++  P I FG   AN +I +A + + S+H+IDLGM     H  QW +L+  LA+R   P  +LRITG+  G++   L+A   +L   A S+ +  EF+ V      L    ++ NL +G+ L VNSI+ LH  VKESRG+L ++LQ + +L+P L+ +VEQD +HNGPFFLGRF+E+LH YSAIFDSL+A LP+   +R KME+  F  EI NI++ EG                   AGFQ   LK ++QA   L +   +GYT+  +KGCL+ GWK +PI+  S W+
Sbjct:  157 LVHLLLACAEALSCRDTRLAETMLSQIWPSVSPWGDSLQRVSFCFAMGLKCRLSHLNNVNAHGTFTIGGAMDRSLIVRAEKMEAFQLLHQATPYIAFGFMAANEAICQAAQEKDSLHIIDLGME----HALQWPSLMRILASRPEGP-PKLRITGLIDGHNLLELEASMKELAEEASSLGIRLEFNLVSEPVSPLLLTTENLNLREGEALFVNSIMHLHKFVKESRGSLKAILQAIKKLNPTLLTVVEQDANHNGPFFLGRFIESLHYYSAIFDSLEASLPRNSPQRIKMEKVQFSTEICNIIAYEGSNRIERHERADQWRRQLSRAGFQVMGLKCMSQARMMLSVYGIDGYTLATEKGCLLLGWKGRPIMLASAWQ 528          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKST-AFSAEKDEALHLV------YEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANR-AGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +L+  L+ACAEAV+  D   A   L+ L       G S QRVASCF + LS RLA      A     P T S+ AFS     ++ ++      Y+ CP ++F HF AN +I EAFE E  VHVIDL +      GYQW   + +LA R  G P   LRITGVG+S E ++  G  L   A S+ + FE+  V     +LKP  FN   G+ L VNS+ +LH   +     L ++L  +   +P ++ +VEQ+ SHNGP+FLGRF+EALH YSAIFDSLD+  P   ++RAK+EQ+ F  EI+NIV+CEG                    GF+  PL    + Q+   L + +C+GY + EDKGCL+ GW+ + I+A S W+
Sbjct:  313 QLLNLLLACAEAVSNEDYMLARRYLHHLNRVVSPLGDSMQRVASCFTEALSARLA------ATLTTKPSTSSSKAFSPFPPNSMEILKIYQILYQACPYVKFAHFTANQAIFEAFETEERVHVIDLDIL----QGYQWPAFMQALAARPGGAPF--LRITGVGSSMENVRETGRCLTELAHSLHVPFEYHPVAEELVDLKPHMFNRRVGEALAVNSVNRLH---RVPGNCLGNLLAMIRDQAPNIVTVVEQEASHNGPYFLGRFLEALHYYSAIFDSLDSTFPPDSSQRAKVEQYIFAPEIRNIVACEGAERFERHERLEKWRKLMEGKGFKGVPLSANAVTQSKILLGLYSCDGYRLTEDKGCLLLGWQDRAILAASAWR 678          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+ ++   A       ++VA+ F + L+ R+  + P            ST  S      +H  YE CP ++F HF AN +ILEAFEG+  VHVID  M  G+    QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   A+++ + FE+   V +S  +L      L   + + VNS+ +LH L+    GA+  VL  + Q+ P+++ +VEQ+ +HNGP FL RF E+LH YS +FDSL+  +    T+   M + Y G++I N+V+CEGP                  AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:  231 RLVHLLMACAEAVQESNFTLAEALVKQIGFLAVSQAGVMRKVATYFAEALARRIYKLCP----------QNSTDHSLSDILQIHF-YETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGM----QWPALMQALALRPGGP-PAFRLTGIGPPAHDNTDHLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPTESVAVNSVFELHKLLSRP-GAIEKVLSVVKQMKPEIVTVVEQEANHNGPIFLDRFTESLHYYSTLFDSLEGSV---STQDKIMSEVYLGKQICNVVACEGPDRVERHETLTQWRTRLGSAGFAPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWR 589          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDV--LVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEA+   +   A  L+  +   A     + ++VA+ F + L+ R+  I P           +     +   + L +  YE CP ++F HF AN +ILEAF   S VHVID G    L  G QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   AQ++ + FEF   V SS  +L+ +  +L   +V  + VNS+ +LH L+ +  G ++ VL ++  + PK++ +VEQ+ +HNGP FL RF EALH YS++FDSL+       ++   M + Y G +I N+V+CEG                   AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:  235 RLVHTLLACAEAIQQENLKLADALVKHIGVLAASQAGAMRKVATYFAEALARRIYKIFP-----------QDHCLDSSYSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFG----LKQGMQWPALMQALALRPGGP-PAFRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVASSLADLEAEMLDLRPPEVEAVAVNSVFELHRLL-DRPGGIDKVLGSIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGVTPTSQDLVMSELYLGRQICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 599          

Query:  424 DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA--------VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +  +LV  L+ACAEAV   +   A  L+ ++   A     + ++VA+ F + L+ R+  + P            ST  S      +H  YE CP ++F HF AN +ILEAFEG+  VHVID  M  G+    QW  L+ +LA R G P    R+TG+G    ++ ++LQ +G  L   A+++ + FE+          +++S   L+P +F  V      VNSI + H L+    GA+  VL  + Q+ P+++ +VEQ+ +HNGP FL RF E+LH YS +FDSL+  +    T+   M + Y  ++I N+V+CEG +                 AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:  228 NGVRLVHLLMACAEAVQENNLNLAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYKLYP----------QNSTDHSLSDILQIHF-YETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGM----QWPALMQALALRPGGP-PAFRLTGIGPPAHDNTDQLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPTEFESV-----AVNSIFEFHKLLAIP-GAMKKVLSVVKQMKPEIVTVVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGSV---STQDKVMSEVYLAKQICNVVACEGSSRVERHETLTQWRTRLSSAGFAPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWR 591          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDV--LVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEA+   +   A  L+  +   A     + ++VA+ F + L+ R+  I P           +     +   + L +  YE CP ++F HF AN +ILEAF   S VHVID G    L  G QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   AQ++ + FEF   V +S  +L  +   L+  +V  + VNS+ +LH L+    G ++ VL+++  + PK++ +VEQ+ +HNGP FL RF EALH YS++FDSL+       ++   M + Y G  I N+V+CEG                   AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:   59 RLVHTLLACAEAIQQENLKLADALVKHIGLLAASQTGAMRKVATYFAEALARRIYKIFP-----------QDYCLDSSCSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFG----LKQGMQWPALMQALALRPGGP-PAFRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVANSLADLDAEMLGLLPPEVEAVAVNSVFELHRLLGRP-GGIDKVLESIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGLTPPSQDLVMSELYLGRHICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 423          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHL-VYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDV--LVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEA+   +   A  L+  +   A     + ++VA+ F + L+ R+  I P           +     +   + L +  YE CP ++F HF AN +ILEAF   S VHVID G    L  G QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   AQ++ + FEF   V +S  +L  +   L+  +V  + VNS+ +LH L+    G ++ VL+++  + PK++ +VEQ+ +HNGP FL RF EALH YS++FDSL+       ++   M + Y G  I N+V+CEG                   AGF P  L      QA   L +    +GY V E+ GCL+ GW ++P+IATS W+
Sbjct:  235 RLVHTLLACAEAIQQENLKLADALVKHIGLLAASQTGAMRKVATYFAEALARRIYKIFP-----------QDYCLDSSCSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFG----LKQGMQWPALMQALALRPGGP-PAFRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVANSLADLDAEMLGLLPPEVEAVAVNSVFELHRLLGRP-GGIDKVLESIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGLTPPSQDLVMSELYLGRHICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 599          

Query:  448 LIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGN--SAER----LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGF-----QPAPLKMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L  CA A++  +   ASTL+ ELR    + G   QR+A+  V+GL+ R+A         L   +      S+++  A+ +++EICP  +FG   AN +++EAF+GE  VH+ID  +      G Q+  LI +LAN  G+  H LR+TGV +  S +R    L+ IG  L+  A++ K++FEF AV S    + P   N   G+ L+VN   QLH +  ES   +N    +L+    L+PKL+ +VEQD + N   F  RF EA + YSA+FDSLDA LP+    R  +E+     +I NIV+CEG                   AGF      P  + MI + +K      C+ Y + ++ G L FGW+ K +I  S WK
Sbjct:  219 LFECANAISEGNIEKASTLINELRQLVSIQGDPPQRIAAYMVEGLAARMAE----SGKYLYKALKCKEPPSSDRLAAMQILFEICPCFKFGFMAANGAMIEAFKGERRVHIIDFDIN----QGSQYITLIQTLANHQGKLPH-LRLTGVDDPESVQRPVGGLRIIGQRLEKLAEAYKVSFEFHAVASKTSLVNPSMLNCKPGEALIVNFAFQLHHMPDESVSTVNERDQLLRMAKSLNPKLVTVVEQDVNTNTAPFFPRFTEAYNYYSAVFDSLDATLPRESQDRLNVEKQCLARDIVNIVACEGEERIERYEVAGKWRARMMMAGFTSCSITPNVVDMIRKLIK----EYCDRYMLKQEVGALHFGWEDKSLIVASAWK 585          

Query:    1 MASGLYVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGS-MCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX-DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-------DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            MAS LYVQ EF G+ TS+EVIG DLNLSSM+CLP+PS LS LE++ A WV PF+D+T +HKRLKQ+H ++Y F   GTNY S Y+GS S MC  G  SLP I FRDHISA+ RRYLA EAMEEA ATLM              D  KLVQQLIACAEAVACRDKAHAS LL+ELRANA+ FGTSFQRV+SCFVQGL+ RLAL+QPLGA G+I P  KS  FSAEK       DEALHLVYEICPQIQFGHFVANASILEAFEG SSVHVIDLGMTLGL HGYQWR+LID LANR GQPLH LRITGVG+S+ERLQAIG+DLKLHAQSMK+N +FS VES+ ENLKPQDF+LVDG++L++NSILQLHCLVKESRG LNS LQTLH+LSPKLM+LVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRR KMEQFYFGEEIKNIVSCEGPA                 AGFQPAPL+ +AQA+KWLE N CEGYTVVEDKGCLV GWKSKPIIATSCWK
Sbjct:  430 MASDLYVQPEFCGEITSNEVIGFDLNLSSMSCLPHPS-LSALEDDSANWVSPFVDKTRNHKRLKQEHDANYGFK-VGTNYSSFYTGSDSNMCTSGFTSLPTIQFRDHISAHKRRYLAAEAMEEAFATLMRDKEDESEEGGGSEDEIKLVQQLIACAEAVACRDKAHASALLFELRANAQAFGTSFQRVSSCFVQGLAXRLALVQPLGAGGVIDPNVKSKPFSAEKGPFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGGSSVHVIDLGMTLGLQHGYQWRDLIDRLANRPGQPLHXLRITGVGSSSERLQAIGDDLKLHAQSMKINXDFSEVESNLENLKPQDFHLVDGEILIINSILQLHCLVKESRGTLNSALQTLHELSPKLMVLVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRVKMEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMRRAGFQPAPLRTMAQAVKWLETNACEGYTVVEDKGCLVLGWKSKPIIATSCWK 951          

Query:   82 SSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGS-------------MCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            S+M C PYP +   LEE   A   P  DE+ +HKRLK+  S S    ++ +++ SLYSG GS                  L++LPR+HFRDHI  YT+RYLA EA+EEA   +           X X   +LVQ LIACAEAVACRDK+HAS LL ELRANA VFG+SFQRVASCFVQGL++RLAL+QPLGAVG IG    +  F+ +K +EAL LVYEICP IQFGHFVAN+SILEAFEGES VHV+DLGMTLGLPHG QW  LI+SLA R GQP  RLRITGVG   +RLQ IG +L+ +A S+ +N EFS V S+ ENL+P D  + DG+VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNI+SCEG                   AGFQ AP+KM+AQA +WL +I  CEGYT++E+KGCLV GWKSKPI+A SCWK
Sbjct:   34 SAMPCYPYPHT-PLLEEGGTASTPPXXDESGNHKRLKRTTSIS----DSMSSHNSLYSGGGSGDSCITDISLSRRSSTNSLNTLPRLHFRDHIWTYTQRYLAAEAVEEAAXXMSNAEGNEEEEDXTXXGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSAMSTKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGDQWXGLIESLATRTGQPPTRLRITGVGLYGDRLQIIGEELEAYADSLGINLEFSVVXSNLENLRPXDIKMYDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEG-RQGGEAREVDQWRRRMSRAGFQAAPIKMLAQAKQWLGKIKVCEGYTILEEKGCLVLGWKSKPIVAASCWK 530          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKD--EALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGV--GNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKP-----QDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            LV  L+ACAEAV CRD   A +LL ++ A+   +G S QRV+ CF  GL  RL+L+Q +   G         + ++  D  EA  L+ +  P I FG  VAN +I +A +G+  +H+IDLGM     H  QW +LI +LA+R   P  +LRITG+   ++   L+A    L   A S+ +  EF  +    E +KP     ++ +  +G+ L VNSI+ LH  VKESRG+L ++LQ L +L P ++ LVEQD +HNGPFFLGRF+E+LH YSAIFDSL+A LP+   +R K+E+ +F +EI+NIV+ EG                   AGFQ   LK  +QA   L +  C+GYT+  +KGCL+ GWK +PI+  S W+
Sbjct:  166 LVHMLLACAEAVGCRDTKLADSLLAQIWASVSPWGDSLQRVSYCFAMGLKSRLSLLQNVNINGTFNNDMMDVSVTSRDDKLEAFQLLNQTTPYIAFGFMVANEAICQAAQGKEDLHIIDLGME----HTLQWPSLIRTLASRXEGPPKKLRITGLVEDHNLFELEAGMRALVEEASSLGIPTEFXLIS---EPVKPSLLTRENLDXREGEALFVNSIMHLHKYVKESRGSLKAILQALKKLGPSVLTLVEQDANHNGPFFLGRFLESLHFYSAIFDSLEASLPRNSPQRMKIERQHFADEIRNIVAFEGLNRIERHERADQWRRQLGRAGFQVMGLKCTSQARMMLSVYGCDGYTLASEKGCLLLGWKGRPIMLASAWQ 537          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLAL-IQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANR-AGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAVA  D   A   L+ L       G S QRVASCF + LS RLA  +    +     P +     S E  +   +VY+ CP I+F HF AN +I EAFE E  VHVIDL +      GYQW   + +LA R  G P   LRITGVG   E ++  G  L   A S+ + FEF AV    E+LKP  FN   G+ L VN++ +LH   + S   L ++L  +   +P ++ LVEQ+ SHNGP+FLGRF+EALH YSAIFDSLDA  P    +RAK+EQ+ F  EI+NIV+CEG                    GF+  PL    + Q+   L + +C+GY + EDKGCL+ GW+ + I+A S W+
Sbjct: 1198 QLVHLLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLTTTPSXSASKPFSPFPPNSFEILKIYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDIL----QGYQWPAFMQALAARPGGAPF--LRITGVGPCIEGVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLH---RVSVNCLGNLLAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGVERTERHERLEKWRKVMESKGFKSVPLSANAVTQSKILLGLYSCDGYRMTEDKGCLLLGWQDRSIMAASAWR 1563          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGA-VGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANR-AGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +L+  L+ CAEAVA  D   A   L+ L       G S QRVASCF   LS RLA             P +     S E  +   +VY+ CP I+F HF AN +I EAFE E  VHVIDL +      GYQW   + +LA R +G P   LRITGVG   E ++  G  L   A S+ + FEF AV    E+LKP  FN   G+ L VN++ +LH   +     L ++L  +   +P ++ LVEQ+ SHNGP+FLGRF+EALH YSAIFDSLDA  P    +RAK+EQ+ F  EI+NIV+CEG                    GF+   L    + Q+   L + +C+GY + ED GCL+ GW+ + I+A S W+
Sbjct:  330 QLLHLLLVCAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTDALSARLAATLTTNPRASAPQPFSPFPPNSLEILKIYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDIL----QGYQWPAFMQALAARPSGAPF--LRITGVGPCIEAVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLH---RVPVNXLGNLLAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGAERTERHERLEKWRKVMESKGFKSVALSANAVTQSKILLGLYSCDGYRMTEDNGCLLLGWQDRSIMAASAWR 695          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTS--FQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEAL-HLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSAVESS-FENLKPQDFNLVDGDVLVVNSILQLHCLV---KESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ CAE+V   D A A +L+  ++A       S    +VA  F+  LS R+   Q +G          S + S  ++E L H  YE CP ++F HF AN +ILEAF+G   VHVID      L HG QW  LI +LA R G P   LR+TG+G    +  + L+ IG  L   A+S+ + F F  V +S  E++KP    +   + + VNSI+QLH L+         +  +L  +  L+PK++ +VEQ+  HN P FL RF EAL+ YS +FDSL+A   + +   A   + Y   EI N+V CEG A                 AGF+P  L      QA   L + + EGY V E++GCL  GW ++P+IA S W+
Sbjct:  156 RLVHLLVTCAESVQRGDLALAGSLIENMQALLTRVNPSCGIGKVAGYFIDALSCRIFSPQTVG----------SASGSVHENELLYHYFYEACPYLKFAHFTANQAILEAFDGHDCVHVID----FNLMHGLQWPALIQALALRPGGP-PLLRLTGIGPPSPDGRDSLREIGLRLAELARSVNVRFXFRGVAASRLEDVKPWMLQVSPKEAVAVNSIMQLHRLLGSDPNRNSPIEMMLSWIRNLNPKIVAVVEQEADHNKPGFLDRFTEALYYYSNMFDSLEACAMQPEKALA---EIYIQREICNVVCCEGAARVERHEPLDKWRIRLEQAGFRPLHLGSNAFKQASMLLTLFSAEGYRVEENQGCLTLGWHNRPLIAASAWQ 521          

Query:  463 EAVACRDKAHASTLLYELRANAKVFGTS--FQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEAL-HLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSAVESS-FENLKPQDFNLVDGDVLVVNSILQLHCLV---KESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            E+V   + A A +L+  ++A      TS    +VA  F+  LS R+   Q +G          S A S  ++E L H  YE CP ++F HF AN +ILEAF G   VHVID      L HG QW  LI +LA R G P   LR+TG+G    +  + L+ IG  L   A+S+ + F F  V +S  E++KP    +   + + VNSI+QLH L+         +  +L  +  L+PK++ +VEQ+  HN P FL RF EAL+ YS +FDSL+A   + +   A+M   Y   EI N+V CEG A                 AGF P  L      QA   L + + EGY V E++GCL  GW S+P+IA S W+
Sbjct:  166 ESVQRGELALAGSLIENMQALMTRVNTSCGIGKVAGYFIDALSRRIFSPQSVG----------SAAGSTHENELLYHYFYEACPYLKFAHFTANQAILEAFHGHDCVHVID----FNLMHGLQWPALIQALALRPGGP-PLLRLTGIGPPSPDGRDSLREIGLRLAELARSVNVRFAFRGVAASRLEDVKPWMLQVSPKEAVAVNSIMQLHRLLGSDPNRNSPIEMMLSWIRNLNPKIVTVVEQEADHNKPGFLDRFTEALYYYSTMFDSLEACPMQPEKTLAEM---YIQREICNVVCCEGAARVERHEPLSKWRTRLGQAGFSPLHLGSNAFKQASMLLTLFSAEGYRVEENQGCLTLGWHSRPLIAASAWQ 521          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQ--DFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAML-PKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+  +   A     + ++VA+ F + L+ R+  I P   +            S+  D      YE CP ++F HF AN +ILEAF   S VHVID G    L  G QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   A+++ + FEF   V SS  +L P   D    +G+V+ VNS+ +LH L+    GA++ VL ++  + PK++ +VEQ+ +HNGP FL RF EALH YS +FDSL+    P  D     M + Y G +I N+++CEG                   AGF P  L      QA   L +    +GY V E+ G L+ GW ++P+IATS W+
Sbjct:  217 RLVHTLMACAEAVQQENLKLADALVKHVGLLAASQTGAMRKVATYFAEALARRIYRIYPQDCLD-----------SSYSDILEMHFYETCPYLKFAHFTANQAILEAFATASRVHVIDFG----LKQGMQWPALMQALALRPGGP-PAFRLTGIGPPQPDNTDALQQVGWKLAQLAETIGVEFEFRGFVASSLADLTPSMLDIRPSEGEVVAVNSVFELHRLLARP-GAVDKVLSSIKAMKPKIVTIVEQEANHNGPVFLDRFTEALHYYSNLFDSLEGSSGPSQD---LVMSEVYLGRQICNVMACEGGDRVERHETLSQWRGRMDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGSLMLGWHTRPLIATSAWQ 578          

Query:  433 KLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVG----NSAERLQAIGNDLKLHAQSMKLNFEFSA-VESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAML-PKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPL--KMIAQAMKWLEINT-CEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            +LV  L+ACAEAV   +   A  L+  +   A       ++VA+ F + L+ R+  I P   +            S+  D      YE CP ++F HF AN +ILEAF   + VHVID G    L  G QW  L+ +LA R G P    R+TG+G    ++ + LQ +G  L   A+++ + FEF   V +S  +L+P   ++   +   VNS+ +LH L+  + GA++ VL ++  + PK+  +VEQ+ +HNGP FL RF EALH YS++FDSL+    P  D     M + Y G +I N+V+CEG                   AGF P  L      QA   L++    +GY V E+ G L+ GW ++P+I TS WK
Sbjct:  215 QLVHTLMACAEAVQQENLKLADALVKHVGLLAAAQTGXMRKVATYFAEALARRIYRIYPQDCLD-----------SSYSDILQMHFYETCPYLKFAHFTANQAILEAFATATRVHVIDFG----LKQGMQWPALMQALALRPGGP-PVFRLTGIGPPQPDNTDVLQQVGWKLAQLAETIGVEFEFRGFVANSLADLEPSMLDIRQDEAXAVNSVFKLHGLLARA-GAVDKVLSSIKAMKPKIXTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSSGPSQD---LVMSEVYLGRQICNVVACEGGDRVERHETLTQWRGRMDSAGFDPVHLGSNAFKQASMLLDLFAGVDGYRVQENNGSLMLGWHTRPLIVTSAWK 574          

Query:  436 LVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAER------LQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNS---VLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQA-MKWLEINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            L + L ACA+A+A  D +    L   LR    V G   QR+ +  ++GL  R A         +   +      SAE    +H++YE+CP  +FG+  AN +I EA + ES VH+ID  +      G QW  LI +LA R G P  ++RITG+ +SA        L  +G  L   A+S K+ FEF A       ++ +D  +  G+ + VN  L LH +  ES  + N    +L+    LSPK++ LVEQ+++ N   FL RF E L  +SA+FDS+D  LP+    R  +EQ     EI NI++CEG                   AGF P PL  +  A +K L  +  E YT+ E  G L  GW ++P++ +  W+
Sbjct:  167 LKEVLCACAKALANNDMSTTEQLFSXLRQMVSVSGEPIQRLGAYILEGLIARXAS----SGSSICASLRCKEPASAELLSYMHILYEVCPYFKFGYMSANGAIAEAMKDESRVHIIDFQVA----QGSQWITLIQALATRPGGP-PQIRITGIDDSASAYVRGGGLGVVGQRLSRLAESCKVPFEFHAAGIFGSEVQLEDLVIRPGEAIAVNFALMLHHIPDESVSSHNHRDRLLRLAKSLSPKVVTLVEQESNTNTAPFLPRFTETLSYFSAVFDSIDVALPREHRERINVEQHCLAREIVNIIACEGAERVERYEPLSKWRSRFIMAGFSPYPLSPLVNATIKTLLQSYSEKYTLEEIGGVLYLGWMNQPLVVSCAWR 537          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX-DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ +N S E  GLDL+LS+MAC P P  L T + N  +W++PF D+T   KR+++   SS    +  +N  SLYSG  S+C       L+S+P++HFRDHI  YT+RYLA EA+EEA +  M              D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG +  +      S +K+EAL LVYEICP I+FGHFVAN +ILEAFEGES VHV+DLGMTLGL HG+QWR LI+SLA RAG+   RLRITGVG   +R + IG++LK +A+ M +N EFSAVES+ ENL+P+D  + +G+VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL  N  C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSGEFNDENVS-ETSGLDLSLSAMACYPRPPYLPTFDSNAVSWILPFSDDTRDAKRMRR---SSSLVESIRSNNSSLYSGGSSICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPTMNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 516          

Query:    1 MASGLYVQAEFSGDNTSDEVIGLDLNLS-SMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            M S LY+Q+E   D T  E  GLDLN+  S+  +P   +       P  + +   DET SHKR+K       E    G    ++ S  GS+ A  L+SLPR+HFRD+I AYT RYLA+EAMEEA A LM             D  KLVQQLIACAEAVACRDK HAS LL ELRANA VFGTSFQRVASCFVQGLSDRL L+QPLGAVG++GP  K+ +F+AEKDEAL LVYEICPQIQFG+FVANA+ILEAFEGESS+HV+DLGMTLGLPHG QWRNL+  LANR  +    LRITGVGNSAERLQA+G++L  +A+S+ LNFEF  VESS E LK  DF L+DG+V+++NSILQLHC VKESRGALN+VLQ LH+LSPKL+ILVEQD+ HNGPFFLGR MEALH YSAIFDSLD MLPKYDT+R K+EQF++GEEIKNIVSCEGPA                 AGFQPA +KM  QA +WL +   CEGYTV EDKGCL+ GWKSKPIIA SCWK
Sbjct:    1 MPSALYMQSESFRDYTRYETTGLDLNIGYSIPHIPVSKN-----SRPTCFDL---DETRSHKRVKP---GGVESIGNGIGCYAVSSNGGSINANCLNSLPRLHFRDYIRAYTERYLAIEAMEEAAAGLMISKKNEIKEEDI-DGMKLVQQLIACAEAVACRDKTHASALLSELRANALVFGTSFQRVASCFVQGLSDRLTLLQPLGAVGVLGPAGKTISFTAEKDEALRLVYEICPQIQFGYFVANATILEAFEGESSIHVVDLGMTLGLPHGEQWRNLLHCLANRPDKKPRCLRITGVGNSAERLQALGDELDCYARSLGLNFEFLWVESSLEKLKSTDFKLLDGEVVIINSILQLHCAVKESRGALNTVLQILHELSPKLLILVEQDSGHNGPFFLGRVMEALHYYSAIFDSLDTMLPKYDTKRVKIEQFFYGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQPAQIKMAMQAKQWLGKAKVCEGYTVTEDKGCLILGWKSKPIIAASCWK 505          

Query:   16 YVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMC----ARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++  EF+ D T  E  GLDL+L++MAC P+P  L   E N  + ++PF DET   KR+KQ  S      + G+   SLYSG  S+C       L+++P++HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK+HAS LL ELR+NA VFG++FQRVASCFVQGL DRL+L+QPLGAVG + P       +++K +EAL LVYEICP I+FGHFVAN SILEAFEGESSVHV+DLGMTLGLPHG+QWR LI SLA RAG+P  RLRITGVG   +R + IG++L+ +A+ M +N EFS V+SS ENL+P+D    + +VLVVNSILQLHC+VKESRGALNSVLQ + +LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLD MLPKYDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL +   C+GYTVVE+KGCLV GWKSKPIIA SCWK
Sbjct:    5 FLSREFN-DETLSETSGLDLSLAAMACYPHPY-LPIFESNVVSRMLPFSDETRDVKRIKQSSSMVESIRSNGS---SLYSGGSSICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWK 515          

Query:   28 EFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGS---------MCARGLDSLPRIHFRDHISAYTRRYLAVEAMEE-ATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEK-DEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            + S D T +E   LD++LS+MA  PYP  L  LE N + +V+ F DET  HK+  ++  S  E   +   Y +  SGSGS              L+SLPR+HFRDHI  YT+RYLA EA+EE A A                D  +LVQ LIACAEAVACRDK+HAS LL ELR++A VFG+SFQRVASCF QGL+DRL+L+QPLG V L+ PI      +++K +EAL LVYEICP IQFGHFVAN+SILEAFEGES VHV+DLGMTLGLPHG+QWR LI SLANRAG+P  RLRIT VG    R Q IG++L  +A+ + +N EFS VES+ ENL+P D  + DG+VLVVNSILQLHC+VKESRGALNSVLQT+H LSPK++ LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLP+YDTRRAKMEQFYF EEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL  N  C+GYTVVE+KGCLV GWKSKPI+A SCWK
Sbjct:    9 DLSHDETINETSSLDISLSAMAYYPYPY-LPILENNESIFVLDFSDETREHKKRIKRALSFAESTGSDGIYNTGGSGSGSGSNDTISRSCSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEGAEAMANSEEGENHGEGGNTDGMRLVQLLIACAEAVACRDKSHASALLSELRSSALVFGSSFQRVASCFFQGLADRLSLVQPLGTVSLVTPIMNIMDIASDKKEEALSLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGHQWRQLIQSLANRAGKPPCRLRITAVGLCVGRFQTIGDELVEYAKDVGINLEFSVVESTLENLQPDDIKVFDGEVLVVNSILQLHCVVKESRGALNSVLQTIHALSPKILALVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPRYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHEKVDQWRRRMSRAGFQAAPVKMMAQAKQWLGKNKVCDGYTVVEEKGCLVLGWKSKPIVAASCWK 525          

Query:   25 AEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAA--WVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSG------------SGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++   +  SDEV GLD +LS+ A   Y  S   + +N +A  W   + DE  +HKRLK+  S +    + G+N  SLYSG            + S     L+SLPR+HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK HAS+LL ELRANA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG I P      TA+  +K+EAL LVYEICP I+FGHFVANASILEAFEGE+  HV+DLGMTLGL HG QWR LI SLANRAG+P  RLRITGVG   +R + IG +L+ +AQ + +N EFSAVES+ ENL+P+D    DG+ LVVNSILQLHC+VKESRGALNSVLQ +++LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSL+AMLPKYDTRRAK+EQFYFGEEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL ++  CEGY ++E+KGCLV GWKSKPI+A SCWK
Sbjct:    3 SDLLSEERSDEVSGLDTSLSAQAY--YSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIA---ESIGSN-SSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWE-KKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLEFSAVESNLENLRPEDIKREDGEALVVNSILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWK 518          

Query:   40 DNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXX--DATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            D  S++ IGL L LS + C PY   L  + +N AA     I +    KRLK+  S     + + T+  S  S + S     L +LPR+ FRDHI  YTRRYLA EA+EEA A ++               D  +LVQ LIACAEAVACRDK+HAS LL ELRANA VFG+SFQRVASCFVQGL+DRLA +QPLGAVG   P       A S EK+EA  LVYEICP IQFGHFVAN+SILEAFEGES VHV+DLGMTLGLP G QWR LI+SLANRAGQP  RLRIT VG   E+ Q+IG++LK +A++  +N EFS VES+ ENL+ +D  +++ +VLVVNSILQLHC+VKESRGALNSVLQ +H+LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDT+RAK+EQFYF EEIKNIVSCEGPA                 AGFQ AP+KMI QA KWL+ N  CEGYTVVE+KGCLV GWKSKPIIAT+CWK
Sbjct:   15 DQRSNQAIGLQLGLSIVDCYPY---LPMMSDNSAA--SSMILQPRDQKRLKRTISVG---DGSPTSTLSRSSSTSS-----LSNLPRLQFRDHIWTYTRRYLAAEAVEEAAAAMIKSEDGCDGDQQDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLADRLASVQPLGAVGSFAPSMNIMDIAGSREKEEAFRLVYEICPHIQFGHFVANSSILEAFEGESLVHVVDLGMTLGLPRGQQWRRLIESLANRAGQPPRRLRITAVGLCVEKFQSIGDELKDYAKTYGINLEFSVVESNLENLQTKDIKVLENEVLVVNSILQLHCVVKESRGALNSVLQIIHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTKRAKIEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMINQAQKWLKNNKVCEGYTVVEEKGCLVLGWKSKPIIATTCWK 508          

Query:    1 MASGLYVQAEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKSTAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLE-INTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            MA  LY+  EF      +E   L L+LS+MA  P+P  L+TL +  + W IPF D T +HKRLK+   +     +   +Y SLY    +     L+SL  + ++DHI    +RYLAVEA+    A ++             D  KLV QLI CA+ VA RDK+HAS LL ELRANA VFGTSFQRVASCFVQGLSDRL+LIQ LGAVG+ G   K+   + EK+EA  L +EICPQIQFGH  ANASILEAFEGESSVHV+DLGM LG P G QWR+L+ SLANRAG+P   L+ITGVG +AE L+ I ++L+++A+S+ +NF+FS VES+ ENL+P+D NL++G+ +VVNSILQLHC+VKESRGALNSVLQ + +LSPK ++LVEQD SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRRAKMEQFYF EEIKNI+SCEG A                 AGFQ +P+KMI +A +WLE +  C+GYT+V++KGCLV GWKSKPIIA SCWK
Sbjct:   16 MAHDLYLPTEFHNGERRNEASALSLSLSAMAGCPFPC-LATLMDISSTWFIPFSDATRNHKRLKRGLGTDQSIRS--NSYSSLYDDGCNGRTNSLNSLLGLQYQDHIWGNAQRYLAVEAIAVDAAAMLGGGVDAVLKEGSDDGMKLVHQLITCAKVVAFRDKSHASALLSELRANALVFGTSFQRVASCFVQGLSDRLSLIQSLGAVGVGGCTVKTMDITPEKEEAFRLFFEICPQIQFGHLAANASILEAFEGESSVHVVDLGMNLGSPQGQQWRSLMHSLANRAGKPPSSLQITGVGTAAECLKDIIDELEVYAESLGMNFQFSMVESNLENLQPEDINLLEGEAVVVNSILQLHCVVKESRGALNSVLQKIRELSPKAVVLVEQDASHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGSARVERHQRLDQWRRRMSRAGFQSSPMKMITEAKQWLEKVKLCDGYTIVDEKGCLVLGWKSKPIIAASCWK 528          

Query:   25 AEFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAA--WVIPFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSG------------SGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITK--STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            ++   +  SDEV GLD +LS+ A   Y  S   + +N +A  W   + DE  +HKRLK+  S +    + G+N  SLYSG            + S     L+SLPR+HFRDHI  YT+RYLA EA+EEA A ++             D  +LVQ LIACAEAVACRDK HAS+LL ELRANA VFG+SFQRVASCFVQGL+DRL+L+QPLGAVG I P      TA+  +K+EAL LVYEICP I+FGHFVANASILEAFEGE+  HV+DLGMTLGL HG QWR LI SLANRAG+P  RLRITGVG   +R + IG +L+ +AQ + +N +                            ILQLHC+VKESRGALNSVLQ +++LSPK+++LVEQD+SHNGPFFLGRFMEALH YSAIFDSL+AMLPKYDTRRAK+EQFYFGEEIKNIVSCEGPA                 AGFQ AP+KM+AQA +WL ++  CEGY ++E+KGCLV GWKSKPI+A SCWK
Sbjct:    3 SDLLSEERSDEVSGLDTSLSAQAY--YSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIA---ESIGSN-SSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWE-KKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLD----------------------------ILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWK 490          

Query:   28 EFSGDNTSDEVIGLDLNLSSMACLPYPSSLSTLEENPAAWVI--PFIDETSSHKRLKQQHSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATATLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVG-LIGPITK-STAFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRA-GQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWLEIN-TCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            E  G+N     +  D+  +++    Y      + EN ++ ++  PF D T      + + +  +   N+ + +    + S S      +S+P++HFRDHI  YT+RYLA E +EEA+                 D  +LVQ LIACAEAVACRDK+HAS LL EL+ANA VFG+SFQRVASCFVQGL++RL LIQP+G+ G ++ P      A S E +EA  LVYE+CP IQFGH++AN+++LEAFEGES VHV+DLGM+LGL HG+QWR LI SLANRA G+ + RLRITGVG    RLQ IG +L ++A ++ +N EFS V  + ENLKP+D  + + +VLVVNSILQLHC+VKESRGALNSVLQ +H L PK++++VEQD+SHNGPFFLGRFME+LH YS+IFDSLD MLPKYDT+RAKMEQFYF EEIKNIVSCEGP                  AGFQ AP+KM+AQ+ +WL  N  CEGYTVVE+KGCLVFGWKS+PI+A SCWK
Sbjct:   11 EIDGENLP---LAFDIWATNLWAYGYYPHQPAISENSSSKLVDFPFCDGTIIRDNKRVKRTVCFPIYNSVSCHSFFNTNSSSR-----NSIPKLHFRDHIRTYTQRYLAAEPVEEASEDTNSSESSGGEEDGCADGVRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLTERLNLIQPIGSAGPMMAPAMNIMDAASDEMEEAYRLVYELCPHIQFGHYLANSTVLEAFEGESFVHVVDLGMSLGLRHGHQWRALIQSLANRASGERVRRLRITGVGLCV-RLQTIGEELSVYANNLGINLEFSVVNKNLENLKPEDIEVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQSKQWLLKNKVCEGYTVVEEKGCLVFGWKSRPIVAVSCWK 513          

Query:  103 YPSSLSTLEENPAA-WVI-PFIDETSS----HKRLKQQ-------------HSSSYEFNNAGTNYCSLYSGSGSMCARGLDSLPRIHFRDHISAYTRRYLAVEAMEEATA-TLMXXXXXXXXXXXXXDATKLVQQLIACAEAVACRDKAHASTLLYELRANAKVFGTSFQRVASCFVQGLSDRLALIQPLGAVGLIGPITKST-----AFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGESSVHVIDLGMTLGLPHGYQWRNLIDSLANRAGQPLHRLRITGVGNSAERLQAIGNDLKLHAQSMKLNFEFSAVESSFENLKPQDFNLVDGDVLVVNSILQLHCLVKESRGALNSVLQTLHQLSPKLMILVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRAKMEQFYFGEEIKNIVSCEGPAXXXXXXXXXXXXXXXXXAGFQPAPLKMIAQAMKWL-EINTCEGYTVVEDKGCLVFGWKSKPIIATSCWK 1545
            YP+ L  LE +  + W++ PF D  +     HK+LK+              HS+S+ FNN  +N  S+            +S+PR+HFRDHI  Y +RY A EA+EEA                   D  +LVQ LIACAEAVACRDK+HAS LL EL++NA VFG+SFQRVASCFVQGL++RL LIQP+G     G  TKS      A S E +EA  LVYE CP IQFGHFVAN+ ILEAFEGES +HV+DLGM+LGLPHG+QWR LI SLA+R+   + RLRIT +G    R+Q IG +L ++A+++ ++ EFS VE + ENLKP+D  + + +VLVVNSILQLHC+VKESRGALN+VLQ +H LSPK++++ EQD+ HNGPFFLGRFME+LH YSAIFDSLDAMLPKYDT+RAKMEQFYF EEIKNIVSCEGP                  AGFQ +P+KM+ QA +WL + N C+GYTVVE+KGCLV GWKSKPI+A SCWK
Sbjct:   29 YPN-LPILENSATSTWILNPFSDHETETIRDHKKLKRSTVTIPIWFANFSSHSNSF-FNNINSNNNSV------------NSIPRLHFRDHIRTYKQRYFASEAVEEAAEDNFNYNNCEAEEDGSCADGMRLVQLLIACAEAVACRDKSHASVLLSELKSNALVFGSSFQRVASCFVQGLTERLTLIQPIGN-NSAGSDTKSMMNIMDAASEEMEEAFKLVYENCPHIQFGHFVANSIILEAFEGESFLHVVDLGMSLGLPHGHQWRGLIQSLADRSSHRVRRLRITAIGLCIARIQVIGEELSIYAKNLGIHLEFSIVEKNLENLKPKDIKVNEKEVLVVNSILQLHCVVKESRGALNAVLQMIHGLSPKVLVMAEQDSGHNGPFFLGRFMESLHYYSAIFDSLDAMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHEKVDQWRRRMSRAGFQGSPIKMVVQAKQWLVKNNVCDGYTVVEEKGCLVLGWKSKPIVAVSCWK 520