ppa023981m, ppa023981m (mRNA) Prunus persica

Query:  418 LDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY---KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            LDE GL L+TLL +CA A+S DN  EA++MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI + L      + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+L++FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSG+ KF  WR +L  ++GF  V ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   HA+
Sbjct:  285 LDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYATLPTVPHSQKLVSAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPFVRLTGLGTSMEALEATGKRLTDFAEKLGLPFEFFPVAEKVGNLDPERLNVSKREAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEQRHAVEQQLLSREIRNVLAVGGPSRSGDVKFNNWREKL-QQSGFRVVSLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHAA 653          

Query:  406 GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLV---------NYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTC 1512
            G  +  + GL L+  L  CA A++ ++   A R L  L+++ +P G S  +RV + F +A+++R+  +     S            N   I   +Q+     P+IKFAHFT+NQAI EAF   +RVH++DLDI+QG QWPA    LA R  G P +R+TGVG S E++ ETG+ L+  A  L + FEFHP+  ++ D+   M   R GE LAV+         T      + +I + AP IVT+VEQ+ S +G  FL RF+ +LHYYS +FDSL++  P D+  R  +E  +F   I NI+A  G  R    ++  +WR  + G+ GF  V +SAN++ Q++++L ++    GY L +  G + LGW+D ++  ASAW C
Sbjct:  292 GSEQEHDSGLQLVHFLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSM-QRVASCFTEALSARLAATLTPKPSTSTTKPFNPFPPNSLEILKIYQILYQACPYIKFAHFTANQAIFEAFEAEERVHVIDLDILQGYQWPAFIQALAARPGGAPFLRITGVGCSPESVRETGRCLTELAHSLHVPFEFHPVGEELEDLKPHMFNRRVGEALAVNSANRLHRVPTNFLGNLLAMIRDQAPNIVTIVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKLEQYIFAPVIRNIVACEGAERVMRHERLEKWRKLMEGK-GFQGVPLSANAVTQSKILLGLY-SCDGYRLTEDKGCLLLGWQDRAILAASAWRC 668          

Query:  448 LLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVIN-----SWLGICSPLVNY-----KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATR---MEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDA-----SMVQVRRGETLAVHWLQHSLYDATGPDWKTMRL----IEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNIL-AIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            LL  CA  +S  +   A R+L  LS  +SP+G S  ER+V  F+ A++ R+       +  G  S   N      ++ HS +   N I+PFI+F+  T+NQAILEA   +  +HILD DIM G+QWP L   +A R   +  PP +R+TG G     L  TG +L  FA+ LGL F+FHP++ +           S +Q+   ETLAV+ + + L+     D + +RL    I+ + P++VT+ E++ + +   FL RFV +L +Y+ +FDSLE+ LP  +  R  VE   F REI +I+ A G   R   ++F  W   L   +GF  V +S  +++QA+L+L +  P+ GY L   + +  LGW++ +L+  S+W
Sbjct:   39 LLISCAELVSQSDFSAARRLLSILSSNSSPFGDS-TERLVHQFSAALSLRLSRYATPATSSGAMSASANTAAADSEAFHSTYLSLNQITPFIRFSQLTANQAILEAIEGQRAIHILDFDIMHGVQWPPLMQAIAERCGNLHPPPMIRITGTGEDLGILQRTGDRLLKFAQSLGLKFQFHPLLLRNDPTSVPLYLPSALQLLPDETLAVNCVLY-LHRLLKDDSRDLRLFLHKIKAMEPKVVTIAEREANHNHPLFLQRFVEALDHYTAVFDSLEATLPPTSRERLAVERIWFGREIVDIVSAEGDNRRERHERFESWEVMLRS-SGFSNVPLSPFALSQAKLLLRLHYPSEGYRLQIINDSFFLGWQNQALFSVSSW 412          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYK--SIHSAFQV---FNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAV------HWLQHSLYDATGPD---------------WKTMRLIEELAPRIVTLVEQDMSQS-GSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQW--RSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            K +E GL LI LL  CA  ++  ++  A+  L  +S +ASP G +  +R+ AYF +A+  R++  W G+   L + K  SI     V   F  + PF+K ++  +NQAI+EA      VHI+DL+  +  QW  L   L+ R EGPP +R+TG+    E L     QL+  A++L + F+F+PIV K+ ++D   ++V+ GE LA+      H L     +  G                    +  +  L+P+++ + EQ+ + +  + ++R + +L++Y+ +FD LES L   +  R  VE  LF  EI NI+A  GP R    +K  +W  R EL    GF +V +S   M QA  +L  +    GY + + +G + + W+D  L+  SAW
Sbjct:   41 KSEERGLYLIRLLVACANHVAAGSIENANIGLEHISHLASPDGDT-VQRIAAYFTEALADRMLKGWPGLHKALNSTKISSISEEILVQKLFFELCPFLKLSYVITNQAIIEAMEGEKMVHIIDLNSFESAQWINLLQSLSARPEGPPHLRITGIHEQKEVLDLMALQLTKEAEKLDIPFQFNPIVSKLENLDFESLRVKTGEALAISSVLQLHTLLAIDDEMVGKSPSASKNTSAVHLQRMGSFLAALWGLSPKLMVVTEQESNNNCPTLMERVMEALNFYAALFDCLESTLSRASIERQKVEKMLFGEEIKNIIACEGPERKERHEKLEKWVMRLELA---GFGRVPLSYQGMLQASRLLVSY-GYDGYRMKEENGCLVICWQDRPLFSVSAW 429          

Query:  448 LLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYK----SIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLME------TGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAV------HWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDM-SQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVE-HCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            +L  CA A++ +++  A   + EL QM S  G    +R+ AY  + + +R+  S   I   L   +     + S   +   I P+ KF H + N AI EA     +VHI+D  I QG+QW  L   LA R  GPPQ+R+TG+  S+            G++LS FA+   + FEFH       ++    +++R GE LAV      H +     D      + +RL++ L+P++VTLVEQ+  + +  FL RF+ +++YY  +F+S++  LP D+  R N E HCL  REI NI+A  G  R    +   +W+S      GF    +S+   A  + +L  +  +  YSL + DG + LGW D +L  A AW+
Sbjct:  159 VLVSCAKAVADNDILRAEWGISELRQMVSVSGEPI-QRLGAYMLEGLVARLAASGSSIYKALRCKEPASAELLSYMHLLFEICPYFKFGHMSGNGAIAEAMKDESKVHIIDFQISQGVQWITLIQALAARPGGPPQIRITGIDDSTSAYARGGGPSIVGQRLSRFAESCKVPFEFHAATISGCEVQLEDLELRPGEALAVNFAFILHHMPDESVDTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAPFLSRFIEAMNYYLAVFESIDVTLPRDHKERINAEQHCL-AREIVNIIACEGAERVERHELLGKWKSRF-LMAGFTPHPLSSYVNATIKTLLQNY--SDKYSLEEKDGALYLGWMDRALVAACAWS 526          

Query:  430 GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVIN----SWLGICSPLVN-----YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGL----QWPALFHILATRMEGPPQ-VRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSF-LDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTC 1512
            G+ L+ LL  CA A++  +   A  +L EL   A  +G S  +RV + F + +  R+        +G  +P +N     ++    A ++   I P IKF HF +N +ILEAF   +  H++DL +  GL    QW  L H LA R   PP+ +R+TGVG   +     G++L  +A+ L              DI+  ++Q           L   + ++ G     ++ I EL+P+++ LVEQD S +G F L RF+ +LHYYS +FDSLE+ LP  +  R  +E   F  EI NI++  GPAR    ++  QWR  +  R GF    +    MAQA+  L       GY++++  G + LGWK   +  AS W C
Sbjct:  144 GMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSF-QRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWEKKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDL--------------DINLDILQ-----------LHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRM-SRAGFQAAPI--KMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWKC 491          

Query:  433 LSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRV--INSW--LGICSPLVNYKSI----HSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIM----QGLQWPALFHILATRMEGPPQ-VRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSF-LDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCS 1515
            + L+  L  CA  ++  +   A  +L EL   A  +G S  +RV + F + ++ R+  I S   +G+    V    I      AF++F  I P I+F H  +N +ILEAF     VH++DL +     QG QW +L H LA R   PP  +++TGVGT++E L +   +L  +A+ LG++F+F  +          +V+  RG   +V                 ++ I EL+P+ V LVEQD S +G F L RF+ +LHYYS +FDSL++ LP  +  R  +E   F  EI NI++  G AR     +  QWR  +  R GF    M    + +A+  L       GY++V   G + LGWK   +  AS W CS
Sbjct:    1 MKLVHQLITCAKVVAFRDKSHASALLSELRANALVFGTSF-QRVASCFVQGLSDRLSLIQSLGAVGVGGCTVKTMDITPEKEEAFRLFFEICPQIQFGHLAANASILEAFEGESSVHVVDLGMNLGSPQGQQWRSLMHSLANRAGKPPSSLQITGVGTAAECLKDIIDELEVYAESLGMNFQFSML--------HCVVKESRGALNSV-----------------LQKIRELSPKAVVLVEQDASHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGSARVERHQRLDQWRRRM-SRAGFQSSPM--KMITEAKQWLEKVKLCDGYTIVDEKGCLVLGWKSKPIIAASCWKCS 347          

Query:  421 DEHGLSLITLLFECAVAISVDNLPE--AHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIH----------SAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGP--PQVRMT------GVGTSSENLMETGKQLSNFAKRLGLSFEFHPI-VRKIGDIDASMVQVRRGETLAVHWLQH-SLYDATGPDWKTMRLI--EELAPRIVTLVEQDMSQS--GSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQ-GDGTIRLGWK 1476
            D  GL L+ LL   A A++  N     A  +L+ L ++ SP   +  ER+ AYF  A+   +  +         +++  H          +AFQ+   +SP++KF HFT+NQAILEA  +  R+HI+D DIM+G+QW +L   L +R +GP  P +R+T      G   S   + ETG++L+ FA  +G  F FH   +        S +++ RGE L ++ + H   +    PD     L   + L P++VTLVE+++  +  G F+ RF+ SLH+YS ++DSLE+  P    +R  VE       I   L      R G++    W   L G  GF  VG+S  +  QA+L+L +F    GY + +  +  + LGWK
Sbjct:   97 DLKGLRLVHLLMAAAEALTGVNKSRDLARVILVRLKELVSPTDGTNMERLAAYFTDALQGLLEGAGAKHMIGNGHHRDDHHHHHHQSDVLAAFQLLQDMSPYVKFGHFTANQAILEAVSKERRIHIVDYDIMEGIQWASLMQALVSRKDGPPAPHLRITALSRGGGGRRSIGTIQETGRRLTAFAASIGQPFSFHQCRLDSDETFRPSALKLVRGEALIINCMLHLPHFSYRAPDSVASFLSGGKTLKPKLVTLVEEEVGPTGDGGFVGRFMDSLHHYSAVYDSLEAGFPMQGRARALVERVFLGPRIAGTLGRIYRGRGGQEG-GSWGEWLDGA-GFRGVGISFANHCQAKLLLGLF--NDGYRVEELANNRMVLGWK 471          

Query:  439 LITLLFECAVAISVDNLPE-AHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHS---AFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEG-PPQVRMTGV------GTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWL--QHSLYDATGPDWK-TMRLIEELAPRIVTLVEQDMS-QSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSG------EDKFRQWRSELGGRNGFMQVGMS--ANSMAQAQLILNMFPP---THGYSLV 1443
            ++  L +CA     D+ P+ A + L+ L +  S +G    ERV  YF++A+ SRV  S      P +   S      +++  N   P+ KFAH T+NQAILEA  R  ++HI+D  I+QG+QW AL   LATR  G P ++R++G+       + + +L  TG +L +FA+ L L+FEF PI+  I +++ S  +V   E LAV+++   ++L D T       +RL + L P+I+TL E +       F++RF  +L YY  +FDSLE  L  D+  R  VE  L  R I  ++   GP   G      EDK  +W+  L    GF  V +S  A+     + + N FPP   T G S V
Sbjct:  219 ILKALLDCARL--ADSEPDRAVKSLIRLRESVSEHGDP-TERVAFYFSEALYSRV--SHQAEKRPTLFETSSEEFTLSYKALNDACPYSKFAHLTANQAILEATERARKIHIVDFGIVQGVQWAALLQALATRSAGKPARIRISGIPAPALGKSPASSLFATGNRLRDFARLLDLNFEFEPILTPIQELNESTFRVDPDEVLAVNFMLQLYNLLDETPVSVNAALRLAKSLNPKIMTLGEYEACLNEVDFINRFKNALRYYRAIFDSLEPNLARDSSDRLQVERLLLGRRIAGVI---GPEEPGTRRERMEDK-EKWKF-LVESCGFESVPLSHYASIDEAWKEVTNRFPPLSKTQGASAV 569          

Query:  481 DNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYK----SIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSE------NLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVH--WLQHSLYDATGPDW----KTMRLIEELAPRIVTLVEQDM-SQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVE-HCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            ++L  A  ++ EL QM S  G    +R+ AY  + + +R+ +S   I   L   +     + S   +   + P+ KF + ++N AI EA    +RVHI+D  I QG QW  L    + R  GPP +R+TG+  S+        L   G++LS  A+ + + FEFH       ++    +  R GE LAV+  ++ H + D +        + +RL++ L+P++VTLVEQ+  + + +F  RF+ +L+YY+ MF+S++  LP ++  R +VE HCL  R++ NI+A  G  R    +   +WR       GF    +S+   A  + +L  +  +  Y L + +G + LGW D  L  + AW
Sbjct:  128 NDLLMAQWLMDELRQMVSVSGEPI-QRLGAYMLEGLVARLASSGSSIYKALRCKEPASADLLSYMHILYEVCPYFKFGYMSANGAIAEAMKDENRVHIIDFQIGQGSQWITLIQAFSARPGGPPHIRITGIDDSTSAYARGGGLNIVGQRLSRLAESVKVPFEFHAADMSGCEVQLENLGARPGEALAVNFAFMLHHMPDESVSTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAAFFPRFLETLNYYTAMFESIDVTLPREHKKRISVEQHCL-ARDVVNIIACEGVERVERHELLGKWRLRF-AMAGFTPYPLSSLVNATIKRLLENY--SDKYRLEEREGALYLGWMDRDLVASCAW 483          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSE--DYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADN------NIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +E+ HG +NMIQ HE W +Y S  VGF   P SNPFP P  IENR + LER+ELS+WVEH+TKQLI                   +      + SSL  +   P K  +RSY D +  ELQW +EL +H  N      + R+  MS++DE+GLSLITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPSCAERVVAYF+KAM SRVINSWLGICSPL+N+KSIH AFQVFN  SPFIKFAHFTSNQ+ILEAFHRRDRVH++DLDIMQGLQWPALFHILATR++GPPQVRMTG+GTS E L+ETG+QLSNFAKRLG+SFEFHPI +K G+IDASMV +RRGET+AVHWLQH+LYDATGPDWKT+RL+E + PR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YLP D+P RH +EHCL YREINNILAIGGPARSGEDKFRQWRSEL  R+ FMQV MS NSMAQAQLILNMFPP HGY+L QG+GT+RLGWKDTSL+ ASAWT + ASR
Sbjct:    5 YEVVHGALNMIQPHETW-DYAS--VGFPA-PISNPFPKPAVIENRCLNLERNELSEWVEHVTKQLIDDLPDIATDHDESLQTDTTTVYGGNDIVSSLLGEF-RPKKYMRRSYFDGNGEELQWSHELGVHQTNISEKEGSTRSPSMSRIDENGLSLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSCAERVVAYFSKAMGSRVINSWLGICSPLINHKSIHGAFQVFNNASPFIKFAHFTSNQSILEAFHRRDRVHVIDLDIMQGLQWPALFHILATRIDGPPQVRMTGMGTSMELLLETGRQLSNFAKRLGMSFEFHPIAKKFGEIDASMVPLRRGETVAVHWLQHTLYDATGPDWKTLRLLEAVGPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLPCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRQWRSEL-ARSSFMQVPMSGNSMAQAQLILNMFPPAHGYNLEQGEGTLRLGWKDTSLFTASAWT-TRASR 514          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADNNIRARG-----MSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +EMAHG +++IQ HEPW +  S   GF   P SNPFP P  IENR V LER+ELS+WVEH+TKQLI                     D  +  SL  D   P K  +RSY D +  ELQW +EL  H  +     G     MS++DE+GL+LITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPS AERVVAYF+KAM SRVINSWLGICSPL+N+KS+HSAFQVFN +SPFIKFAHFTSNQAILEAF RRD VHI+DLDIMQGLQWPALFHILATR+EGPPQVRMTG+G+S E L+ETGKQLSNFA+RLGL FEFHPI +K G+ID SMV +RRGETLAVHWLQHSLYDATGPDWKT+RL+E LAPR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YL  D+P RH +EHCL YREINNILAIGGPARSGEDKFR WRSEL  +N FMQV MS NSMAQAQLILNMFPP HGY+LVQGDGT+RLGWKDTSL+ ASAWT S ASR
Sbjct:    5 YEMAHGALDLIQPHEPWDHCAS--AGFPA-PISNPFPKPV-IENRCVNLERNELSEWVEHVTKQLIDDVPDTETHDSLQTDTRMVYGDNNIVPSLLGDHFRPKKSMRRSYFDGNGEELQWSHELGEHQASISEKEGSARSSMSRIDENGLNLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSSAERVVAYFSKAMGSRVINSWLGICSPLINHKSVHSAFQVFNNVSPFIKFAHFTSNQAILEAFQRRDSVHIIDLDIMQGLQWPALFHILATRIEGPPQVRMTGMGSSMEVLVETGKQLSNFARRLGLPFEFHPIAKKFGEIDVSMVPLRRGETLAVHWLQHSLYDATGPDWKTLRLLEALAPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLHCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRHWRSEL-AKNSFMQVAMSGNSMAQAQLILNMFPPAHGYNLVQGDGTLRLGWKDTSLFTASAWT-SRASR 512          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXX-----SEDYFVPSSLSTDLITPSKISQRSYGD-----HDHELQW-----GNELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRN-GFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +E+ +G ++M+Q+HE W +Y S V GFQ    SN FP     +     LER+ELS+WVEH+T+QLI                        S +  VPS L++D   P K  +RS+ D     H+ ELQW     GN+++++ +     RG+S++DEHGL+LI+LLFECAVAISVDNL EAHRMLLEL+QMASPYGPSCAERVVAYFAKAM SRVINSWLGICSPL+N+K++HSAFQVFN +SPFIKFAHF SNQ ILEAF RRDRVHI+DLDIMQGLQWPALFHILATRMEGPP +RMTG+GTS + L+ETGKQLSNFAKRLGLSFEFHPI +K G+ID SMV +RRGETLAVHWLQHSLYDATGPDWKTMRL+EEL+PRI+TLVEQD+S  GSFLDRFVGSLHYYST+FDSL ++LP D+ SRH VEHCL YREINN+LAIGGPARSGEDK R WRSEL  R+  FMQV MS NSMAQAQLILNMFPP HGYSL QG+G +RLGWKDTSL+ ASAWT S ASR
Sbjct:    5 YEVVNGAIDMMQTHEAW-DYGSSV-GFQAAAASNSFP-----KQVVTNLERNELSEWVEHVTRQLIDDMPDTPSDHSLQTDTAMVCNEDSSNNNVVPSLLTSDS-RPRKALKRSHFDGAYSIHEEELQWSNIELGNQIRINENGASNGRGLSRIDEHGLNLISLLFECAVAISVDNLGEAHRMLLELTQMASPYGPSCAERVVAYFAKAMASRVINSWLGICSPLINHKTVHSAFQVFNNVSPFIKFAHFISNQEILEAFQRRDRVHIIDLDIMQGLQWPALFHILATRMEGPPHIRMTGMGTSMDLLVETGKQLSNFAKRLGLSFEFHPIAKKFGEIDVSMVPLRRGETLAVHWLQHSLYDATGPDWKTMRLLEELSPRIMTLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAFLPCDDSSRHRVEHCLLYREINNVLAIGGPARSGEDKLRHWRSELAARSTSFMQVPMSGNSMAQAQLILNMFPPAHGYSLAQGEGALRLGWKDTSLFTASAWT-SLASR 519          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRAR----GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            FE+ HG +++IQ HE W      ++G Q   +SN FP P  +ENR   LER+ELS+WVEH+TKQLI                        V   L T+ +T         G     LQWGNE      NN+       G+S+LDEHGL LITLL ECAVAISVDNL EAHRMLLEL+QMASPYG SCAERVV+YFAKAM SRVINSWLG+CSPL+++K++HS+ Q+FN ISPFIKFAHFTSNQ+ILEAFHRRD VHI+DLDIMQGLQWPALFHILATR+EGPP +RMTG+G+S E L +TGKQLSNFA+RLGLSFEFHP+ +K G+I D + +Q+RRGETLAVHWLQHSLYDATGPDWKT+RL+EELAPR++TLVEQ++S  GSFLDRFVGSLHYYST+FDSL +  PSD+P RH VEHCL YREINNI+AIGGPARSGEDKFRQWRSE+  RN F+QV MS N+MAQAQLILNMFPP HGYSLV+G+GT+RLGWKDT LY ASAWT SHA R
Sbjct:    5 FEVVHGALDLIQPHEQWEYN---IIGLQGASSSN-FPKPMVVENRS-NLERNELSEWVEHVTKQLIEDLPET------------------VGEGLKTEEVTIVG------GSFAPVLQWGNEAAGSQSNNLSTGDINGGLSRLDEHGLGLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGASCAERVVSYFAKAMASRVINSWLGLCSPLISHKAVHSSLQIFNNISPFIKFAHFTSNQSILEAFHRRDLVHIIDLDIMQGLQWPALFHILATRIEGPPHIRMTGMGSSIELLTQTGKQLSNFARRLGLSFEFHPVAKKFGEINDITSLQIRRGETLAVHWLQHSLYDATGPDWKTIRLLEELAPRVITLVEQEISHGGSFLDRFVGSLHYYSTIFDSLGASFPSDDPGRHRVEHCLLYREINNIMAIGGPARSGEDKFRQWRSEMAARNCFVQVPMSGNAMAQAQLILNMFPPAHGYSLVKGEGTLRLGWKDTGLYSASAWT-SHAYR 487          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRAR----GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            FE+ HG +++IQ HE W      ++G Q   +SN FP P  +ENR   LER+ELS+WVEH+TKQLI                        V   L T+ +T         G     LQWGNE      NN+       G+S+ DEHGL LITLL ECAVAISVDNL EAHRMLLEL+QMASPYG SCAERVV+YFAKAM SRVINSWLG+CSPL+++K++HS+ Q+FN ISPFIKFAHFTSNQ+ILEAFHRRD VHI+DLDIMQGLQWPALFHILATR+EGPP +RMTG+G+S E L +TGKQLSNFA+RLGLSFEFHP+ +K G+I D + +Q+RRGETLAVHWLQHSLYDATGPDWKT+RL+EELAPR++TLVEQ++S  GSFLDRFVGSLHYYST+FDSL +  PSD+P RH VEHCL YREINNI+AIGGPARSGEDKFRQWRSE+  RN F+QV MS N+MAQAQLILNMFPP HGYSLVQG+GT+RLGWKDT LY ASAWT
Sbjct:    5 FEVVHGALDLIQPHEQWEYN---IIGLQGASSSN-FPKPMVVENRS-NLERNELSEWVEHVTKQLIEDLPET------------------VGEGLKTEEVTIVG------GSFAPVLQWGNEAAGSQSNNLSTGDINGGLSRPDEHGLGLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGASCAERVVSYFAKAMASRVINSWLGLCSPLISHKAVHSSLQIFNNISPFIKFAHFTSNQSILEAFHRRDMVHIIDLDIMQGLQWPALFHILATRIEGPPHIRMTGMGSSIELLTQTGKQLSNFARRLGLSFEFHPVAKKFGEINDITSLQIRRGETLAVHWLQHSLYDATGPDWKTIRLLEELAPRVITLVEQEISHGGSFLDRFVGSLHYYSTIFDSLGASFPSDDPGRHRVEHCLLYREINNIMAIGGPARSGEDKFRQWRSEMAARNCFVQVPMSGNAMAQAQLILNMFPPAHGYSLVQGEGTLRLGWKDTGLYSASAWT 482          

Query:    4 FEMAHGTMN--MIQSH--EPWTNYPSPVVG--FQNNPTSNPFPIPKPIENRFVTLERSELSQWVEH----ITKQLIXXXXXXXXXXXXXXXXXXXSEDYF---VPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            FE+ H   N  MI  H  E W +Y + +    F     SNP+P P    N  + L ++EL  W+E     ITK  +                      +    VPS LS +         R   +          L +  + +   +    + + GL+LITLL ECAVAISVDNL EAHRMLLEL+QMASPY  SCAERVVAYFAKAMTSRV+NSWLG+CSPLV++KSI+SAFQVFN ISPFIKFAHFTSNQAILEA    D +HI+DLDIMQGLQWPA FHILATRMEG P+V MTG+G S E L+ETGKQL+NFA+RLGLS +FHPI  K G+ ID SM+ V+ GE +AVHWLQHSLYDATGPDWKT+RL+EEL PRI+TLVEQD++  GSFLDRFV SLHYYST+FDSL +YL +D+ +RH VEH L  REINN+LAIGGP RSGED FRQWRSEL       QV +S NSMAQAQLILNMF P +GYSL Q +GT+RLGWKDTSLY ASAWTC ++S
Sbjct:    5 FEVIHANYNPNMIHPHMHETWDHYSNTITSLPFSAPTPSNPYPKPATENNHCLNLGQNELCDWMEEHISDITKHFVEDLPETTTSDNLLSNNPTGVVSHHNLGVPSLLSPNFTQRKPSCFRPQFESFTNDPPNFNLHIQTNTSTLDQNKHNVYDQGLNLITLLMECAVAISVDNLGEAHRMLLELTQMASPYKASCAERVVAYFAKAMTSRVMNSWLGVCSPLVDHKSINSAFQVFNNISPFIKFAHFTSNQAILEAVSHCDSIHIIDLDIMQGLQWPAFFHILATRMEGKPKVTMTGLGASMELLVETGKQLTNFARRLGLSLKFHPIATKFGEVIDVSMLHVKPGEAVAVHWLQHSLYDATGPDWKTLRLLEELEPRIITLVEQDVNHGGSFLDRFVASLHYYSTLFDSLGAYLHNDDSNRHRVEHGLLSREINNVLAIGGPKRSGEDNFRQWRSELARHCFVKQVPLSDNSMAQAQLILNMFSPAYGYSLAQVEGTLRLGWKDTSLYTASAWTCCNSS 525          

Query:  433 LSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQ--SGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTS 1485
            LSLITLL ECAVAISVDNL EAHRMLLEL+Q++SPY  SCAERVVAYFAKAMTSRV+NSWLG+CSPLV++KSI+S+FQVFN ISPFIKFAHFTSNQAILEA    D +HI+DLDIMQGLQWPA FHILATRMEG PQV MTG G S E L+ETGKQL+NFA+RLG+S +F PI  KIG+ ID S + V+ GE +AVHWLQHSLYDATGPDWKT+RL+EEL PRI+TLVEQD++    GSFLDRFV SLHYYST+FDSL +YL +D+ +RH VEH L  REINN+L IGGP RS EDKFRQWR+EL       QV MSANSMAQAQLILNMF P +GYSL Q +GT+RLGWKDTS
Sbjct:    1 LSLITLLMECAVAISVDNLGEAHRMLLELTQVSSPYKASCAERVVAYFAKAMTSRVMNSWLGVCSPLVDHKSINSSFQVFNNISPFIKFAHFTSNQAILEAVSHCDSIHIIDLDIMQGLQWPAFFHILATRMEGKPQVTMTGFGASMELLVETGKQLTNFARRLGMSLKFLPIATKIGEVIDVSTLHVKPGEAVAVHWLQHSLYDATGPDWKTLRLLEELEPRIITLVEQDVNHGGGGSFLDRFVASLHYYSTLFDSLGAYLHNDDENRHRVEHGLLSREINNVLGIGGPKRS-EDKFRQWRNELARHCFVKQVPMSANSMAQAQLILNMFSPAYGYSLAQVEGTLRLGWKDTS 353          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-----PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            K DE GL L+TLL +CA A+S DN  EA++MLLE+SQ+++PYG S A+RV AYF++AM++R+INS LGI +     PL + + + SAFQVFN ISPF+KF+HFT+NQAI EAF R DRVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +L  ++GF  + ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   HA+
Sbjct:  446 KRDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISQLSTPYGTS-AQRVAAYFSEAMSARLINSCLGIYATLPSMPLTHTQKMASAFQVFNGISPFVKFSHFTANQAIQEAFEREDRVHIIDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSIEALEATGKRLSDFAQKLGLPFEFFPVADKVGNLDPDRLNVSKREAVAVHWLQHSLYDVTGSDSNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEVKFHNWREKL-RQSGFKGISLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHAT 817          

Query:  367 ELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPL----VNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            EL +        +   K DE GL L+TLL +CA A+S +NL +A++MLLE+SQ+++P+G S A+RV AYF++A+++R+++S LGI + L    ++ + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G+ID   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL S    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +L  + GF  + ++ N+  QA L+L MF P+ GY+LV+ +G ++LGWKD  L  ASAW
Sbjct:  411 ELAITRKKKEEIKEQKKKDEEGLHLLTLLLQCAEAVSAENLEQANKMLLEISQLSTPFGTS-AQRVAAYFSEAISARLVSSCLGIYATLPPHTLHNQKVASAFQVFNGISPFVKFSHFTANQAIQEAFDREERVHIIDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSMETLEATGKRLSDFASKLGLPFEFFPVAEKVGNIDVEKLNVSKSEAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSNAGSFLGRFVEAIHYYSALFDSLGSSYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEIKFHNWREKL-QQCGFRGISLAGNAATQASLLLGMF-PSEGYTLVEDNGILKLGWKDLCLLTASAW 791          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY---KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            K DE GL L+TLL +CA A+S DN  EA++MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI + L      + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+L++FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSG+ KF  WR +L  ++GF  V ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   HA+
Sbjct:  402 KRDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYATLPTVPHSQKLVSAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPFVRLTGLGTSMEALEATGKRLTDFAEKLGLPFEFFPVAEKVGNLDPERLNVSKREAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEQRHAVEQQLLSREIRNVLAVGGPSRSGDVKFNNWREKL-QQSGFRVVSLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHAA 771          

Query:  367 ELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLV------NYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            EL L        +   K DE GL L+TLL +CA A+S +NL +A++MLLE+SQ+++P+G S A+RV AYF++A+++R+++S LGI + L       + + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G+ID   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL S    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +L  + GF  V ++ N+  QA L+L MF P+ GY+LV+ +G ++LGWKD  L  ASAW
Sbjct:  423 ELALARKKKEEIKEQKKKDEEGLHLLTLLLQCAEAVSAENLEQANKMLLEISQLSTPFGTS-AQRVAAYFSEAISARLVSSCLGIYATLPVSSHTPHNQKVASAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSMETLEATGKRLSDFANKLGLPFEFFPVAEKVGNIDVEKLNVSKSEAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSNAGSFLGRFVEAIHYYSALFDSLGSSYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEIKFHNWREKL-QQCGFRGVSLAGNAATQASLLLGMF-PSEGYTLVEDNGILKLGWKDLCLLTASAW 805          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-------PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            K DE GL L+TLL +CA A+S DNL EA+++LLE+SQ+++PYG S A+RV AYF++AM++R++NS LGI +       P  +   + SAFQVFN ISP +KF+HFT+NQAI EAF + D VHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G++D   + VR+ E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  +EI N+LA+GGP+RSGE KF  WR ++  + GF  + ++ N+  QA L+L MF P+ GY+LV  +GT++LGWKD SL  ASAWT
Sbjct:  282 KQDEEGLHLLTLLLQCAEAVSADNLEEANKLLLEISQLSTPYGTS-AQRVAAYFSEAMSARLLNSCLGIYAALPSRWMPQTHSLKMVSAFQVFNGISPLVKFSHFTANQAIQEAFEKEDSVHIIDLDIMQGLQWPGLFHILASRPGGPPHVRLTGLGTSMEALQATGKRLSDFADKLGLPFEFCPLAEKVGNLDTERLNVRKREAVAVHWLQHSLYDVTGSDAHTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSKEIRNVLAVGGPSRSGEVKFESWREKM-QQCGFKGISLAGNAATQATLLLGMF-PSDGYTLVDDNGTLKLGWKDLSLLTASAWT 650          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-------PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            K DE GL L+TLL +CA A++ DNL EA+RMLL++S++++PYG S A+RV AYF++AM++R++NS LGI +       PL   + + SAFQVFN ISPF+KF+HFT+NQAI EAF R DRVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +   ++GF  V ++ N+ AQA L+L MF  + GY+L + +G ++LGWKD  L  ASAW
Sbjct:  409 KKDEEGLHLLTLLLQCAEAVAADNLDEANRMLLQVSELSTPYGTS-AQRVAAYFSEAMSARLVNSCLGIYASAPLNALPLSLNQKMASAFQVFNGISPFVKFSHFTANQAIQEAFEREDRVHIIDLDIMQGLQWPGLFHILASRPGGPPLVRLTGLGTSMEALEATGKRLSDFAQKLGLPFEFFPVADKVGNLDPQRLNVNKREAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGACYGEESEERHAVEQQLLSREIRNVLAVGGPSRSGEVKFNNWREKF-QQSGFRGVSLAGNAAAQATLLLGMF-HSDGYTLAEDNGALKLGWKDLCLLTASAW 776          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVN--------YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            DE GL L+TLL +CA +++ DNL EAHR LLE++++A+P+G S  +RV AYFA+AM++R+++S LG+ +PL N        +  + +AFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP+VR+TG+G S E L  TGK+LS+FA  LGL FEF P+  K G++D   + V R E +AVHWL+HSLYD TG D  T+ LI+ LAP++VT+VEQD+S SGSFL RFV ++HYYS +FDSL++    D+P RH VE  L  REI N+LA+GGPAR+G+ KF  WR +L  ++GF    ++ ++ AQA L+L MF P+ GY+L++ +G ++LGWKD  L  ASAW    AS
Sbjct:  285 DEEGLHLLTLLLQCAESVNADNLDEAHRALLEIAELATPFGTS-TQRVAAYFAEAMSARLVSSCLGLYAPLPNPSPAAARLHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCPVADKAGNLDPEKLGVTRREAVAVHWLRHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSFLARFVEAIHYYSALFDSLDASYSEDSPERHVVEQQLLSREIRNVLAVGGPARTGDVKFGSWREKL-AQSGFRVSSLAGSAAAQAALLLGMF-PSDGYTLIEENGALKLGWKDLCLLTASAWRPIQAS 657          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVN--------YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            DE GL L+TLL +CA +++ DNL EAHR LLE++++A+P+G S  +RV AYFA+AM++R+++S LG+ +PL N        +  + +AFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP+VR+TG+G S E L  TGK+LS+FA  LGL FEF P+  K G++D   + V R E +AVHWL+HSLYD TG D  T+ LI+ LAP++VT+VEQD+S SGSFL RFV ++HYYS +FDSL++    D+P RH VE  L  REI N+LA+GGPAR+G+ KF  WR +L  ++GF    ++ ++ AQA L+L MF P+ GY+L++ +G ++LGWKD  L  ASAW    AS
Sbjct:  277 DEEGLHLLTLLLQCAESVNADNLDEAHRALLEIAELATPFGTS-TQRVAAYFAEAMSARLVSSCLGLYAPLPNPSPAAARLHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCPVADKAGNLDPEKLGVTRREAVAVHWLRHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSFLARFVEAIHYYSALFDSLDASYSEDSPERHVVEQQLLSREIRNVLAVGGPARTGDVKFGSWREKL-AQSGFRVSSLAGSAAAQAVLLLGMF-PSDGYTLIEENGALKLGWKDLCLLTASAWRPIQAS 649          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVN--------YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            DE GL L+TLL +CA +++ DNL EAHR LLE++++A+P+G S  +RV AYFA+AM++R+++S LG+ +PL +        +  + +AFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP+VR+TG+G S E L  TGK+LS+FA  LGL FEF P+  K G++D   + V R E +AVHWL+HSLYD TG D  T+ LI+ LAP++VT+VEQD+S SGSFL RFV ++HYYS +FDSL++    D+P RH VE  L  REI N+LA+GGPAR+G+ KF  WR +L  ++GF    ++ ++ AQA L+L MF P+ GY+L++ +G ++LGWKD  L  ASAW    AS
Sbjct:  286 DEEGLHLLTLLLQCAESVNADNLDEAHRALLEIAELATPFGTS-TQRVAAYFAEAMSARLVSSCLGLYAPLPSPSPAGARVHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCPVADKAGNLDPEKLGVTRREAVAVHWLRHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSFLARFVEAIHYYSALFDSLDASYSEDSPERHVVEQQLLSREIRNVLAVGGPARTGDVKFGSWREKL-AQSGFRVSSLAGSAAAQAALLLGMF-PSDGYTLIEENGALKLGWKDLCLLTASAWRPIQAS 658          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVN--------YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            DE GL L+TLL +CA +++ DNL EAHR LLE++++A+P+G S  +RV AYFA+AM++R+++S LG+ +PL +        +  + +AFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP+VR+TG+G S E L  TGK+LS+FA  LGL FEF P+  K G++D   + V R E +AVHWL+HSLYD TG D  T+ LI+ LAP++VT+VEQD+S SGSFL RFV ++HYYS +FDSL++    D+P RH VE  L  REI N+LA+GGPAR+G+ KF  WR +L  ++GF    ++ ++ AQA L+L MF P+ GY+L++ +G ++LGWKD  L  ASAW    AS
Sbjct:  286 DEEGLHLLTLLLQCAESVNADNLDEAHRALLEIAELATPFGTS-TQRVAAYFAEAMSARLVSSCLGLYAPLPSPSPAGARVHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCPVADKAGNLDPEKLGVTRREAVAVHWLRHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSFLARFVEAIHYYSALFDSLDASYSEDSPERHVVEQQLLSREIRNVLAVGGPARTGDVKFGSWREKL-AQSGFRVSSLAGSAAAQAALLLGMF-PSDGYTLIEENGALKLGWKDLCLLTASAWRPIQAS 658          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVN--------YKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            DE GL L+TLL +CA A++ DNL +AH+ LLE++++A+P+G S  +RV AYFA+AM++R+++S LG+ +PL          +  + +AFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP+VR+TG+G S E L  TGK+LS+FA  LGL FEF  +  K G++D   + V R E +AVHWL HSLYD TG D  T+ LI+ LAP++VT+VEQD+S SGSFL RFV ++HYYS +FDSL++    D+P RH VE  L  REI N+LA+GGPAR+G+ KF  WR +L  ++GF    ++ ++ AQA L+L MF P+ GY+LV+ +G ++LGWKD  L  ASAW
Sbjct:  293 DEEGLHLLTLLLQCAEAVNADNLDDAHQTLLEIAELATPFGTS-TQRVAAYFAEAMSARLVSSCLGLYAPLPPGSPAAARLHGRVAAAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPRVRLTGLGASMEALEATGKRLSDFADTLGLPFEFCAVAEKAGNVDPEKLGVTRREAVAVHWLHHSLYDVTGSDSNTLWLIQRLAPKVVTMVEQDLSHSGSFLARFVEAIHYYSALFDSLDASYGEDSPERHVVEQQLLSREIRNVLAVGGPARTGDVKFGSWREKL-AQSGFRAASLAGSAAAQASLLLGMF-PSDGYTLVEENGALKLGWKDLCLLTASAW 659          

Query:  433 LSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWL-GICSPL-------VNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMS--QSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            + L++LL +CA  ++ D+L EA  +L E+S++ SP+G S  ERVVAYFA+A+ +RVI+S+L G CSPL       V  + I SA Q +N++SP IKF+HFT+NQAI +A    D VHI+DLD+MQGLQWPALFHILA+R      +R+TG G+SS+ L  TG++L++FA  L L FEFHPI   IG+ ID S +  R+GE + VHW+QH LYD TG + +T+ ++  L P ++T+VEQ++S    GSFL RFV +LHYYS +FD+L   L  ++  R  VE  +   EI NI+A GG    G  K  +W+ EL  R GF  V +  N   QA L+L M  P +GY+LV+ +GT+RLGWKD SL  ASAW
Sbjct:   38 IKLLSLLLQCAEYVATDHLREASTLLSEISEICSPFGSS-PERVVAYFAQALQTRVISSYLSGACSPLSEKPLTVVQSQKIFSALQTYNSVSPLIKFSHFTANQAIFQALDGEDSVHIIDLDVMQGLQWPALFHILASRPRKLRSIRITGFGSSSDLLASTGRRLADFASSLNLPFEFHPIEGIIGNLIDPSQLATRQGEAVVVHWMQHRLYDVTGNNLETLEILRRLKPNLITVVEQELSYDDGGSFLGRFVEALHYYSALFDALGDGLGEESGERFTVEQIVLGTEIRNIVAHGG----GRRKRMKWKEEL-SRVGFRPVSLRGNPATQAGLLLGML-PWNGYTLVEENGTLRLGWKDLSLLTASAW 399          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQV-----FNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSS----ENLMETGKQLSNFAKRLGLSFEFHPIV-RKIGDIDASMVQVRRGETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSD-NPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            E G+ L+  L  CA A+  +NL  A  ++ ++  +A         +V  YFA+ +  R+          L   K + S+F       F    P++KFAHFT+NQAILEAF  + RVH++D  + QG+QWPAL   LA R  GPP  R+TG+G  S    ++L E G +L+  A+ + + FE+   V   + D+DASM+++R GE++AV+  +  HSL    G   + +  ++++ P IVT+VEQ+ + +G  FLDRF  SLHYYST+FDSLE    S  N     +      ++I N++A  GP R    +   QWR+ LG   GF  V + +N+  QA ++L +F    GY + + +G + LGW    L   SAW
Sbjct:  209 ETGIRLVHTLMACAEAVQQENLKLAEALVKQIGFLAVSQA-GAMRKVATYFAEGLARRIYR--------LYPDKPLDSSFSDILQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMKQGMQWPALMQALALRPGGPPSFRLTGIGPPSTDNTDHLHEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRDGESVAVNSVFELHSLLARPGGIERVLSAVKDMKPDIVTIVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGCGVSPVNTQDKLMSEVYLGQQICNVVACEGPERVERHETLAQWRARLGSA-GFDPVNLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAW 574          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-------PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            K DE GL L+TLL +CA A+S DNL EA+++LLE+SQ+++PYG S A+RV AYF++AM++R++NS LGI +       P  +   + SAFQVFN ISP +KF+HFT+NQAI EAF + D VHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G++D   + VR+ E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  +EI N+LA+GGP+RSGE KF  WR ++  + GF  + ++ N+  QA L+L MF P+ GY+LV  +GT++LGWKD SL  ASAWT
Sbjct:  282 KQDEEGLHLLTLLLQCAEAVSADNLEEANKLLLEISQLSTPYGTS-AQRVAAYFSEAMSARLLNSCLGIYAALPSRWMPQTHSLKMVSAFQVFNGISPLVKFSHFTANQAIQEAFEKEDSVHIIDLDIMQGLQWPGLFHILASRPGGPPHVRLTGLGTSMEALQATGKRLSDFADKLGLPFEFCPLAEKVGNLDTERLNVRKREAVAVHWLQHSLYDVTGSDAHTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSKEIRNVLAVGGPSRSGEVKFESWREKM-QQCGFKGISLAGNAATQATLLLGMF-PSDGYTLVDDNGTLKLGWKDLSLLTASAWT 650          

Query:  433 LSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWL-GICSPL-------VNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMS--QSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            + L++LL +CA  ++ D+L EA  +L E+S++ SP+G S  ERVVAYFA+A+ +RVI+S+L G CSPL       V  + I SA Q +N++SP IKF+HFT+NQAI +A    D VHI+DLD+MQGLQWPALFHILA+R      +R+TG G+SS+ L  TG++L++FA  L L FEFHPI   IG+ ID S +  R+GE + VHW+QH LYD TG + +T+ ++  L P ++T+VEQ++S    GSFL RFV +LHYYS +FD+L   L  ++  R  VE  +   EI NI+A GG    G  K  +W+ EL  R GF  V +  N   QA L+L M  P +GY+LV+ +GT+RLGWKD SL  ASAW
Sbjct:   38 IKLLSLLLQCAEYVATDHLREASTLLSEISEICSPFGSS-PERVVAYFAQALQTRVISSYLSGACSPLSEKPLTVVQSQKIFSALQTYNSVSPLIKFSHFTANQAIFQALDGEDSVHIIDLDVMQGLQWPALFHILASRPRKLRSIRITGFGSSSDLLASTGRRLADFASSLNLPFEFHPIEGIIGNLIDPSQLATRQGEAVVVHWMQHRLYDVTGNNLETLEILRRLKPNLITVVEQELSYDDGGSFLGRFVEALHYYSALFDALGDGLGEESGERFTVEQIVLGTEIRNIVAHGG----GRRKRMKWKEEL-SRVGFRPVSLRGNPATQAGLLLGML-PWNGYTLVEENGTLRLGWKDLSLLTASAW 399          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSW---LGICSPLVNYKSIH----SAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVH---WLQHSLYDATGPDWKT-MRLIEELAPRIVTLVEQDMSQSGSFLD-RFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGED-KFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMF-PPTHGYSLVQGD-----------GTIRLGWKDTSLYVASAWT 1509
            +    L+ LL  C  AI   N+   +  +     +ASP G +   R++AY+ +A+  RV   W     I  P    +++     +A +  N ++P  KF HFT+N+ +L AF  ++RVHI+D DI QGLQWP+ F  LA+R+  P  VR+TG+G S   L ETG +L  FA+ + L FEFHP+V ++ D+   M+ V+ GE++AV+    +  +LYD TG   +  + LI    P  + L EQ+   +   L+ R   SL YYS MFD++ + L +D+  R  VE  LF REI NI+A  G  R      FR WR  L  + GF  +G+S   + Q++++L M+     G+  V+             G + L W +  LY  SAWT
Sbjct:  269 QRDFELVNLLTGCLDAIRSRNIAAINHFIARTGDLASPRGRTPMTRLIAYYIEALALRVARMWPHIFHIAPPREFDRTVEDESGNALRFLNQVTPIPKFIHFTANEMLLRAFEGKERVHIIDFDIKQGLQWPSFFQSLASRINPPHHVRITGIGESKLELNETGDRLHGFAEAMNLQFEFHPVVDRLEDVRLWMLHVKEGESVAVNCVMQMHKTLYDGTGAAIRDFLGLIRSTNPIALVLAEQEAEHNSEQLETRVCNSLKYYSAMFDAIHTNLATDSLMRVKVEEMLFGREIRNIVACEGSHRQERHVGFRHWRRML-EQLGFRSLGVSEREVLQSKMLLRMYGSDNEGFFNVERSDEDNGGEGGRGGGVTLRWSEQPLYTISAWT 654          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQV-FNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPI-VRKIGDIDASMVQVRRG-ETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFY-REINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            E G+ L+  L  CA A+  +NL  A  ++  +  +AS        +V  YFA+ +  R+   +       V   S     Q+ F    P++KFAHFT+NQAILE F   ++VH++DL +  GLQWPAL   LA R  GPP  R+TG+G S  ++ E G +L   A  +G++FEF  I +  + D+   M+ +R G E++AV+  +  H L    G   K +  I+ + P I+T+VEQ+ + +G+ FLDRF  SLHYYS++FDSLE       PS+  V   LF  R+I N++A  G  R    +   QWR+   G  GF  V + +N+  QA ++L ++    GY++ + +G + LGW+   L   SAW
Sbjct:  147 ETGVRLVHALLACAEAVQQNNLKLADALVKHVGLLASSQA-GAMRKVATYFAEGLARRIYRIYP---RDDVALSSFSDTLQIHFYESCPYLKFAHFTANQAILEVFATAEKVHVIDLGLNHGLQWPALIQALALRPNGPPDFRLTGIGYSLTDIQEVGWKLGQLASTIGVNFEFKSIALNNLSDLKPEMLDIRPGLESVAVNSVFELHRLLAHPGSIDKFLSTIKSIRPDIMTVVEQEANHNGTVFLDRFTESLHYYSSLFDSLEG-----PPSQDRVMSELFLGRQILNLVACEGEDRVERHETLNQWRNRF-GLGGFKPVSIGSNAYKQASMLLALYAGADGYNVEENEGCLLLGWQTRPLIATSAW 505          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY--KSIHSAFQV-FNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVG----TSSENLMETGKQLSNFAKRLGLSFEFHPIV-RKIGDIDASMVQVRRGETLAVH----WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            E+G+ L+  L  CA AI  +NL  A  ++ ++  +A         +V  YFA+A+  R+        SP  N     +    Q+ F    P++KFAHFT+NQAILEAF  + RVH++D  + QGLQWPAL   LA R  GPP  R+TG+G     +S++L E G +L+  A+ + + FE+   V   + D+DASM+++R  +T AV     +  H L    G   K + +++++ P I T+VEQ+ + +G  FLDRF  SLHYYST+FDSLE    S +     V      ++I N++A  GP R    +   QW +  G  +G     + +N+  QA ++L++F    GY + + +G + LGW    L   SAW  S A+
Sbjct:  216 ENGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQA-GAMRKVATYFAEALARRIYR-----LSPPQNQIDHCLSDTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGLQWPALMQALALREGGPPTFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRPGGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQDKVMSEV---YLGKQICNLVACEGPDRVERHETLSQWGNRFGS-SGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWKLSTAA 586          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMA-SPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSS----ENLMETGKQLSNFAKRLGLSFEFHPIV-RKIGDIDASMVQVRRG--ETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMS-QSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCS 1515
            E+G+ L+  L  CA A+  +NL  A  ++ ++  +A S  G     +V  YFA+A+  R+    L      +++    +    F    P++KFAHFT+NQAILEAF  + RVH++D  + QGLQWPAL   LA R  GPP  R+TG+G  +    + L E G +L++ A+ + + FE+   V   + D+DASM+++R    E++AV+  +  H L    G   K + ++ ++ P I T+VEQ+ +  S  FLDRF  SLHYYST+FDSLE  +PS       +      ++I N++A  GP R    +   QWR+  G   GF    + +N+  QA ++L +F    GY + + DG + LGW    L   SAW  S
Sbjct:  164 ENGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIG--AMRKVATYFAEALARRIYR--LSPSQSPIDHSLSDTLQMHFYETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGLQWPALMQALALRPGGPPVFRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEIESVAVNSVFELHKLLGRPGAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEG-VPSGQDK--VMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSA-GFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWKLS 531          

Query:  382 ADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLG---ICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVG----TSSENLMETGKQLSNFAKRLGLSFEFHPI-VRKIGDIDASMVQVR-RGETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSG-SFLDRFVGSLHYYSTMFDSLE-SY-LPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            +D + R+  +    E G+ L+  L  CA AI  +NL  A  ++  +  +A     +   +V  YFA+A+  R+   +     +C+  VN          F    P++KFAHFT+NQAILEA     RVH++DL + QG+QWPAL   LA R  GPP  R+TG+G     +S++L + G +L+ FA+ +G+ FEF  +    + D++  M + R   ETL V+  +  H L   +G   K +  ++ + P IVT+VEQ+ + +G  FLDRF  +LHYYS++FDSLE SY LPS +     V      R+I N++A  G  R    +   QWR  +    GF  + + +++  QA ++L+++    GY + + DG + +GW+   L   SAW
Sbjct:  161 SDESTRSVVLVDSQETGVRLVHALVACAEAIHQENLNLADALVKRVGTLAGSQAGAMG-KVATYFAQALARRIYRDYTAETDVCAA-VNPSFEEVLEMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGMQWPALMQALALRPGGPPSFRLTGIGPPQTENSDSLQQLGWKLAQFAQNMGVEFEFKGLAAESLSDLEPEMFETRPESETLVVNSVFELHRLLARSGSIEKLLNTVKAIKPSIVTVVEQEANHNGIVFLDRFNEALHYYSSLFDSLEDSYSLPSQDRVMSEV---YLGRQILNVVAAEGSDRVERHETAAQWRIRMKSA-GFDPIHLGSSAFKQASMLLSLYATGDGYRVEENDGCLMIGWQTRPLITTSAW 544          

Query:  403 RGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSS--ENLMETGKQLSNFAKRLGLSFEFHPI-VRKIGDIDASMVQVR-RGETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLES--YLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            R +  ++E G+ L+  L  CA A+ ++NL  A  ++  +  +A+    +   +V  YFA+A+  R+        +   +++ I      F    P++KFAHFT+NQAILEA      VH++DL + QG+QWPAL   LA R  GPP  R+TGVG  S  E + E G +L+  A+ +G+ F+F+ +   ++ D++  M + R   ETL V+  +  H +    G   K +  ++ + P +VT+VEQ+ + +G  FLDRF  +LHYYS++FDSLE    +PS +     V      R+I N++A  G  R    +   QWR  +G   GF  V + +++  QA L+L +     GY + + DG++ L W+   L  ASAW
Sbjct:  145 RSVVLIEETGVRLVQALVACAEAVQLENLSLADALVKRVGLLAASQAGAMG-KVATYFAEALARRIYRIHPSAAAIDPSFEEILQ--MNFYDSCPYLKFAHFTANQAILEAVTTSRVVHVIDLGLNQGMQWPALMQALALRPGGPPSFRLTGVGNPSNREGIQELGWKLAQLAQAIGVEFKFNGLTTERLSDLEPDMFETRTESETLVVNSVFELHPVLSQPGSIEKLLATVKAVKPGLVTVVEQEANHNGDVFLDRFNEALHYYSSLFDSLEDGVVIPSQDRVMSEV---YLGRQILNLVATEGSDRIERHETLAQWRKRMGSA-GFDPVNLGSDAFKQASLLLALSGGGDGYRVEENDGSLMLAWQTKPLIAASAW 515          

Query:  439 LITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEG-PPQVRMTGV-----GTSSE-NLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWL--QHSLYDATGPDWKT-MRLIEELAPRIVTLVEQDMSQSG-SFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFR-----QWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQG-DGTIRLGWKDTSLYVASAW 1506
            L+  +++CA  IS  +  EA + LL++ +  S  G    ERV  YF +A+++R+  +     S   + + +  +++  N   P+ KFAH T+NQAILEA  + +++HI+D  I+QG+QWPAL   LATR  G P Q+R++G+     G S E +L+ TG +L +FAK L L+F+F PI+  I  ++ S  +V   E LAV+++   + L D T     T +RL + L PR+VTL E ++S +   F +R   +L +YS +F+SLE  L  D+  R  VE  LF R I+ ++   GP ++G  + R     QWR  L    GF  V +S  +++QA+++L  +  ++ YS+V+   G I L W D  L   S+W
Sbjct:  217 LLKAIYDCA-RISDSDPNEASKTLLQIRESVSELGDP-TERVAFYFTEALSNRLSPNSPATSSSSSSTEDLILSYKTLNDACPYSKFAHLTANQAILEATEKSNKIHIVDFGIVQGIQWPALLQALATRTSGKPTQIRVSGIPAPSLGESPEPSLIATGNRLRDFAKVLDLNFDFIPILTPIHLLNGSSFRVDPDEVLAVNFMLQLYKLLDETPTIVDTALRLAKSLNPRVVTLGEYEVSLNRVGFANRVKNALQFYSAVFESLEPNLGRDSEERVRVERELFGRRISGLI---GPEKTGIHRERMEEKEQWR-VLMENAGFESVKLSNYAVSQAKILLWNYNYSNLYSIVESKPGFISLAWNDLPLLTLSSW 583          

Query:  448 LLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRV-----------INSWL--------------GICSP--LVNYKSIHSAFQV-----FNTISPFIKFAHFTSNQAILEAFHRRDR--VHILDLDIMQGLQWPALFHILATRMEGP----PQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVR-------RGETLAV---HWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSG-SFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            LLF  A  +S  N   A  +L  LS  +SP+G S  ER+V  F KA++ R+           + +W                +C    L   K+ +S F+       N ++PFI+F H T+NQAIL+A    D   +HILDLDI QGLQWP L   LA R   P    P +R+TG G     L  TG +L+ FA  LGL F+FH +V    D+   ++Q+R       +GET+AV   H+L     D        +  I+ L  RIVT+ E++ +    SFL+RF  ++ +Y  +FDSLE+ LP ++  R  +E   F +EI +++A     R    +  +   E+  R GF+ V + + +++QA+L+L +  P+ GY+L   + ++ LGW++  L+  S+W
Sbjct:   44 LLFTAANFVSQSNFTAAQNLLSILSLNSSPHGDS-TERLVHLFTKALSVRINRQQQDQTAETVATWTTNEMTMSNSTVFTSSVCKEQFLFRTKNNNSDFESCYYLWLNQLTPFIRFGHLTANQAILDATETNDNGALHILDLDISQGLQWPPLMQALAERSSNPSSPPPSLRITGCGRDVTGLNRTGDRLTRFADSLGLQFQFHTLVIVEEDLAGLLLQIRLLALSAVQGETIAVNCVHFLHKIFNDDGDMIGHFLSAIKSLNSRIVTMAEREANHGDHSFLNRFSEAVDHYMAIFDSLEATLPPNSRERLTLEQRWFGKEILDVVAAEETERKQRHRRFEIWEEMMKRFGFVNVPIGSFALSQAKLLLRLHYPSEGYNLQFLNNSLFLGWQNRPLFSVSSW 444          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADNNIRARG-----MSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +EMAHG +++IQ HEPW +  S   GF   P SNPFP P  IENR V LER+ELS+WVEH+TKQLI                     D  +  SL  D   P K  +RSY D +  ELQW +EL  H  +     G     MS++DE+GL+LITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPS AERVVAYF+KAM SRVINSWLGICSPL+N+KS+HSAFQVFN +SPFIKFAHFTSNQAILEAF RRD VHI+DLDIMQGLQWPALFHILATR+EGPPQVRMTG+G+S E L+ETGKQL+NFA+RLGL FEFHPI +K G+ID SMV +RRGETLAVHWLQHSLYDATGPDWKT+RL+E LAPR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YL  D+P RH +EHCL YREINNILAIGGPARSGEDKFR WRSEL  +N FMQV MS NSMAQAQLILNMFPP HGY+LVQGDGT+RLGWKDTSL+ ASAWT S ASR
Sbjct:    5 YEMAHGALDLIQPHEPWDHCAS--AGFPA-PISNPFPKPV-IENRCVNLERNELSEWVEHVTKQLIDDVPDTETHDSLQTDTRMVYGDNNIVPSLLDDHFRPKKSMRRSYFDGNGEELQWSHELGEHQASISEKEGSARSSMSRIDENGLNLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSSAERVVAYFSKAMGSRVINSWLGICSPLINHKSVHSAFQVFNNVSPFIKFAHFTSNQAILEAFQRRDSVHIIDLDIMQGLQWPALFHILATRIEGPPQVRMTGMGSSMEVLVETGKQLTNFARRLGLPFEFHPIAKKFGEIDVSMVPLRRGETLAVHWLQHSLYDATGPDWKTLRLLEALAPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLHCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRHWRSEL-AKNSFMQVAMSGNSMAQAQLILNMFPPAHGYNLVQGDGTLRLGWKDTSLFTASAWT-SRASR 512          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSE--DYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADN------NIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +E+ HG +NMIQ  E W +Y S  VGF   P SNPFP P  IENR + LER+ELS+WVEH+TKQLI                   +      + SSL  +   P K  +RSY D +  ELQW +EL +H  N      + R+  MS++DE+GLSLITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPSCAERVVAYF+KAM SRVINSWLGICSPL+N+KSIH AFQVFN  SPFIKFAHFTSNQ+ILEAFHRRDRVH++DLDIMQGLQWPALFHILATR++GPPQVRMTG+GTS E L+ETG+QLSNFAKRLG+SFEFHPI +K G+IDASMV +RRGET+AVHWLQH+LYDATGPDWKT+RL+E + PR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YLP D+P RH +EHCL YREINNILAIGGPARSGEDKFRQWRSEL  R+ FMQV MS NSMAQAQLILNMFPP HGY+L QG+GT+RLGWKDTSL+ ASAWT + ASR
Sbjct:    5 YEVVHGALNMIQPRETW-DYAS--VGFPA-PISNPFPKPAVIENRCLNLERNELSEWVEHVTKQLIDDLPDIATDHDESLQTDTTTVYGGNDIVSSLLGEF-RPKKYMRRSYFDGNGEELQWSHELGVHQTNISEKEGSTRSPSMSRIDENGLSLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSCAERVVAYFSKAMGSRVINSWLGICSPLINHKSIHGAFQVFNNASPFIKFAHFTSNQSILEAFHRRDRVHVIDLDIMQGLQWPALFHILATRIDGPPQVRMTGMGTSMELLLETGRQLSNFAKRLGMSFEFHPIAKKFGEIDASMVPLRRGETVAVHWLQHTLYDATGPDWKTLRLLEAVGPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLPCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRQWRSEL-ARSSFMQVPMSGNSMAQAQLILNMFPPAHGYNLEQGEGTLRLGWKDTSLFTASAWT-TRASR 514          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIH-----SAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            K DE GL L+TLL +CA A+S DN  EA++MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI + L +    H     SAFQVFN I PF+KF+HFT+NQAI EAF R +RVHI+DLD+MQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G+++   + V + E +AVHWLQHSLYD TG D   + L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSG+ KF  WR +L  ++GF  + ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   H +
Sbjct:  404 KRDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYATLPSMPQSHTQKMASAFQVFNGIGPFVKFSHFTANQAIQEAFEREERVHIIDLDVMQGLQWPGLFHILASRPGGPPYVRLTGLGTSLEALEATGKRLSDFAHKLGLPFEFIPVAEKVGNLEPERLNVSKREAVAVHWLQHSLYDVTGSDTNMLCLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGDVKFHNWREKL-QQSGFKGISLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHVT 775          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIH-----SAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            K +E GL L+TLL +CA A+S DN  EA++MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI + L +    H     SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS+E L  TGK+LS+FA +LGL FEF P+  K+G+++   + V + E +AVHWLQHSLYD TG D   + L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSG+ KF  WR +L  ++GF  + ++ N+  QA L+L MF P+ GY+L +  GT++LGWKD  L  ASAW   H S
Sbjct:  456 KRNEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYATLPSMPQSHTQKMASAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPFVRLTGLGTSTEALEATGKRLSDFANKLGLPFEFIPVAEKVGNLNPERLNVSKSEAVAVHWLQHSLYDVTGSDTNMLYLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAVHYYSALFDSLGASYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGDVKFHNWREKL-QQSGFKCISLAGNAANQANLLLGMF-PSDGYTLAEDKGTLKLGWKDLCLLTASAWRPFHVS 827          

Query:  430 GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY-------KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            GL L+ LL +CA  +++DNL +A  +L E+++++SP+G S  ERV AYFA A+ +RV+ S LG  SPLV+        + + +A Q +N+ISP +KF+HFT+NQAI +A    DRVH++DLDIMQGLQWP LFHILA+R +    +R+TG G+SSE L  TG++L++FA  LGL FEFHP+  KIG++ D S + VR  E + VHW+ H LYD TG D  T++L+  L P+++T VEQD+S  GSFL RFV +LHYYS +FD+L   L  D+  RH VE  LF  EI NI+A+GGP R+GE K  +W  EL  R GF  V +  +  AQA L+L MF P  GY+LV+ +G+++LGWKD SL  ASAW
Sbjct:   46 GLRLLGLLLQCAECVAMDNLNDATDLLPEIAELSSPFGSS-PERVGAYFAHALQARVVGSCLGTYSPLVSKSVTLTQSQRLFNALQSYNSISPLVKFSHFTANQAIFQALDGEDRVHVIDLDIMQGLQWPGLFHILASRPKKIRSMRITGFGSSSELLESTGRRLADFASSLGLPFEFHPLEGKIGNVTDLSQLGVRPREAIVVHWMHHCLYDVTGSDLGTLKLLTLLRPKLITTVEQDLSHGGSFLGRFVEALHYYSALFDALGDGLGVDSVERHMVEQQLFGCEIRNIVAVGGPKRTGEVKVERWGDEL-RRVGFEPVSLGGSPAAQASLLLGMF-PWKGYTLVEENGSLKLGWKDLSLLTASAW 409          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY-------KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDA-SMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            +  GL L+ LL +CA  +++DNL  A  +L E++++++P+G S  ERV AYFA A+  RV++S LG  SPLV+        + + +A Q +N+ISP +KF+HFT+NQAI +A    DRVH++DLDIMQGLQWP LFHILA+R      +R+TG G+SSE L  TG++L++FA  LGL FEFHP+  KIG++   S + VR  E + VHW+ H LYD TG D +T++L+  L P+++T VEQD+S  GSFL RFV +LHYYS +FD+L   L  D+  RH VE  LF  EI NI+A+GGP R+GE K  +W  EL  R+GF  V +  N  AQA L+L MF P  GY+LV+ +G ++LGWKD SL  ASAW
Sbjct:   74 ESSGLRLLGLLLQCAECVAMDNLNGATDLLPEIAELSTPFGSS-PERVGAYFAHALQVRVVSSILGTYSPLVSKSVTRTQSQKLFNALQSYNSISPLVKFSHFTANQAIFQALDGEDRVHVIDLDIMQGLQWPGLFHILASRPRKIRSMRITGFGSSSELLESTGRRLADFASSLGLPFEFHPLEGKIGNVTGLSQLGVRPREAIVVHWMHHCLYDVTGSDLETLKLLALLRPKLITTVEQDLSHGGSFLGRFVEALHYYSALFDALGDGLGVDSVERHMVEQQLFGCEIRNIVAVGGPKRTGEVKVERWGDEL-RRSGFRPVSLQGNPAAQAGLLLGMF-PWRGYTLVEENGCLKLGWKDLSLLTASAW 440          

Query:  406 GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVI--------NSWLGICSPLV-NYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTC 1512
            G  +  + GL L+ LL  CA A+S ++   A R L  L+++ SP G S  +RV + F +A+++R+          S     SP   N   I   +Q+     P++KFAHFT+NQAI EAF   +RVH++DLDI+QG QWPA    LA R  G P +R+TGVG+S EN+ ETG+ L+  A  L + FE+HP+  ++ D+   M   R GE LAV+ +              + +I + AP IVT+VEQ+ S +G  FL RF+ +LHYYS +FDSL+S  P D+  R  VE  +F  EI NI+A  G  R    ++  +WR  + G+ GF  V +SAN++ Q++++L ++    GY L +  G + LGW+D ++  ASAW C
Sbjct:  303 GSEQEQDSGLQLLNLLLACAEAVSNEDYMLARRYLHHLNRVVSPLGDSM-QRVASCFTEALSARLAATLTTKPSTSSSKAFSPFPPNSMEILKIYQILYQACPYVKFAHFTANQAIFEAFETEERVHVIDLDILQGYQWPAFMQALAARPGGAPFLRITGVGSSMENVRETGRCLTELAHSLHVPFEYHPVAEELVDLKPHMFNRRVGEALAVNSVNRLHRVPGNCLGNLLAMIRDQAPNIVTVVEQEASHNGPYFLGRFLEALHYYSAIFDSLDSTFPPDSSQRAKVEQYIFAPEIRNIVACEGAERFERHERLEKWRKLMEGK-GFKGVPLSANAVTQSKILLGLY-SCDGYRLTEDKGCLLLGWQDRAILAASAWRC 679          

Query:  343 DHELQWGNELQLHADNN-IRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSW---LGICSPLVNYK---SIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVH---WLQHSLYDATGPDWKT-MRLIEELAPRIVTLVEQDMSQSGSFLD-RFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQG--DGTIRLGWKDTSLYVASAWT 1509
            +HE+  G+    H     + A    + +  G  L++ L  C   I + N+   +  + +L ++ASP G   + R+ AY+ +A+  RV   W     I +P    +      +A ++ N +SP  KF HFT+N+ +L AF  +DRVHI+D DI QGLQWP+LF  LA+R   P  VR+TG+G S + L ETG +L+ FA+ L L FEFHP+V ++ D+   M+ V+  E +A++    +  +LYD +G   +  + LI    P IV L EQ+   +   L+ R   SL YYS +FDS++S LP ++P R  +E  ++ REI N++A  G  R    + F +W+ +L  + G   VG+    M QAQ++L M+         QG  +  + L W D  LY  SAWT
Sbjct:  250 EHEVGKGSSNPPHPQEGAVEAAEDDQREHQGFELVSFLTACVEEIGLKNIASINHFIAKLGELASPKGIPIS-RLAAYYTEALALRVTRIWPHIFHITAPRELDRVDDDSGTALRLLNQVSPIPKFIHFTANEMLLRAFEGKDRVHIIDFDIRQGLQWPSLFQSLASRTNPPSHVRITGIGESKQELNETGDRLAGFAEALNLPFEFHPVVDRLEDVRLWMLHVKERECVAINCIFQMHKTLYDGSGGALRDFLGLIRSTNPTIVLLAEQEAEHNAPNLETRVCNSLKYYSAIFDSIDSSLPFNSPVRIKLEE-MYAREIRNVVACEGSDRHERHESFDKWK-KLMEQGGLRCVGIDEREMLQAQMLLKMYSCDSYKVKKQGHEEAALTLSWLDQPLYTVSAWT 650          

Query:  424 EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQV-FNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVG----TSSENLMETGKQLSNFAKRLGLSFEFHPIV-RKIGDIDASMVQVRRGETLAVH--WLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            E+G+ L+ LL  CA A+   N   A  ++ ++  +A         +V  YFA+A+  R+      +C       S+    Q+ F    P++KFAHFT+NQAILEAF  + RVH++D  + QG+QWPAL   LA R  GPP  R+TG+G     ++++L E G +L+  A+ + + FE+   V   + D+DASM+++R  E++AV+  +  H L    G   K + +++++ P IVT+VEQ+ + +G  FLDRF  SLHYYST+FDSLE  + + +     V      ++I N++A  GP R    +   QWR+ LG   GF  V + +N+  QA ++L +F    GY + + +G + LGW    L   SAW
Sbjct:  227 ENGIRLVHLLMACAEAVQESNFTLAEALVKQIGFLAVSQA-GVMRKVATYFAEALARRIYK----LCPQNSTDHSLSDILQIHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGMQWPALMQALALRPGGPPAFRLTGIGPPAHDNTDHLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPTESVAVNSVFELHKLLSRPGAIEKVLSVVKQMKPEIVTVVEQEANHNGPIFLDRFTESLHYYSTLFDSLEGSVSTQDKIMSEV---YLGKQICNVVACEGPDRVERHETLTQWRTRLGSA-GFAPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAW 588          

Query:  430 GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSW---LGICSPLVNYK---SIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVH---WLQHSLYDATGPDWKT-MRLIEELAPRIVTLVEQDMSQSGSFLD-RFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFP------PTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            G  L++LL  C  AI++ N+   +  L EL  +ASP G   + R+ AY+ +A+  RV   W     I +P    +      +A ++ N +SP  KF HFT+N+ +L AF  +DRVHI+D DI QGLQWP LF  LA+R   P  VR+TG+G S + L ETG +L+ FA+ L L FEFHP+V ++ D+   M+ V+  E +A++    +  +LYD +G   +  + LI    P IV + EQ+   +   L+ R   SL YYS +FDS++S LP D+P R  +E  ++ REI NI+A  G  R    +      +L  + G   + +S   M Q+Q++L M+         HG    Q    + L W D  LY  SAWT
Sbjct:  281 GFELVSLLTACVEAITLKNIAGINHFLAELGGLASPKGIPIS-RLAAYYTEALALRVTRLWPHIFHITAPRELDRVDDDSGTALRLLNQVSPIPKFIHFTANEMLLRAFEGKDRVHIIDFDIKQGLQWPTLFQSLASRTNPPSHVRITGIGESKQELNETGDRLAGFAEALNLPFEFHPVVDRLEDVRLWMLHVKERECVAINCVFQMHKTLYDGSGGALRDFLGLIRSTNPAIVIVAEQEAEHNAPNLETRVCNSLKYYSALFDSIDSSLPFDSPVRIKIEE-MYAREIRNIVACEGSDRHERHEMLDNWKKLMEQGGLRCLVISEREMLQSQILLKMYSCDSYQVKKHG----QEGAALTLSWLDQPLYTVSAWT 651          

Query:   10 MAHGTMNMIQSHEPWTNYPSPVV-GFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXX-SEDYFVPSSLSTDLITPSKISQRSYGDHD-HELQWGNELQLHADNN-IRARG---MSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQ-------------GLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            MA GT+ +IQSH+PW NYP+P V GFQNNP S+P    KP+ENRF+ LERSELS WVEHI+KQLI                    SEDYFVPSSLSTDL +P K+ +RSYG+H+ HELQ GNELQL ADNN +RARG   MSKLDEHGL+LITLLFECAVAISVDNLPEAHRMLLEL+QMASPYGPSCAERVVAYFAKAM SRVINSWLGI SPLVNYKS+H AFQVFNTISPFIKFAHFTSNQAILEAFH  D VHILDLDIMQ             GLQWPALFHILATRMEGPP VRMTG+GTSSE L+ETGKQLS+FA+RLGLSFEFHPIVRK+G++DASMVQVRRGETLAVHWLQHSLYDATGPDWK MR IEELAPRI+TLVEQDMS SGSFLDRFVGSLHYYSTMFDSLESYLPSDNP+RH VEHCLFYREINNILAIGGPARSGEDKFRQWRSELG R+ FMQVGMS NSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS+
Sbjct:    1 MADGTVXIIQSHQPWINYPNPNVNGFQNNPNSDP----KPVENRFINLERSELSLWVEHISKQLIDDLPEPATAANTAANDTLQTSEDYFVPSSLSTDLNSPRKVPRRSYGEHELHELQRGNELQLLADNNNVRARGGNDMSKLDEHGLALITLLFECAVAISVDNLPEAHRMLLELTQMASPYGPSCAERVVAYFAKAMASRVINSWLGISSPLVNYKSVHGAFQVFNTISPFIKFAHFTSNQAILEAFHHHDMVHILDLDIMQQERNFNKKSKMHKGLQWPALFHILATRMEGPPHVRMTGMGTSSEILLETGKQLSSFARRLGLSFEFHPIVRKVGEVDASMVQVRRGETLAVHWLQHSLYDATGPDWKAMRFIEELAPRIITLVEQDMSHSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPNRHKVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGARSEFMQVGMSGNSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASK 522          

Query:  106 PFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGDHDH-ELQWGNELQLHADNN-IRARG---MSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            P P PKP+ENRF+ LERSELSQWVEHITK LI                   SEDYFVPSSLSTDLI+P K+ +RSYG+H+H ELQWGNELQLHADN+ +RARG   MSKLDEHGL+LITLLFECAVAISVDNLPEAHRMLLEL+ MASPYGPSCAERVVAYFAKAM SRVI+SWLGICSPL+NYKS+HSAFQVFNTISPFIKFAHFTSNQAILEAFH RDRVHILDLDIMQGLQWPALFHILATRMEGPP +RMTGVGTSSE L+ETGKQLSNFAKRLGLSFEFHPIVR +G++DASMVQV+RGETLAVHWLQHSLYDATG DWKT+RLIEELAPR+VTLVEQDMS SGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRH VEH +FYREINNILAIGGPARSGEDKFRQWRSELG R+ FMQV MS NSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR
Sbjct:    9 PSPNPKPVENRFINLERSELSQWVEHITKHLIDDLPEPATTNTASTDTLQTSEDYFVPSSLSTDLISPRKVPRRSYGEHEHHELQWGNELQLHADNSDVRARGGNNMSKLDEHGLTLITLLFECAVAISVDNLPEAHRMLLELTHMASPYGPSCAERVVAYFAKAMASRVISSWLGICSPLINYKSVHSAFQVFNTISPFIKFAHFTSNQAILEAFHHRDRVHILDLDIMQGLQWPALFHILATRMEGPPHLRMTGVGTSSEILLETGKQLSNFAKRLGLSFEFHPIVRTVGEVDASMVQVQRGETLAVHWLQHSLYDATGSDWKTLRLIEELAPRLVTLVEQDMSHSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHKVEHSMFYREINNILAIGGPARSGEDKFRQWRSELGARSEFMQVEMSGNSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 487          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-------PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            K DE GL L+TLL +CA A+S DN  EA +MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI +       P+   + + SAFQVFN ISPF+KF+HFT+NQAI EAF   DRVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E    TGK+LS+FA +LGL FEF P+  K+G++D   + + + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +   ++GF  + ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW
Sbjct:  448 KRDEEGLHLLTLLLQCAEAVSADNYDEATKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYASLPHSSVPITYTQKMVSAFQVFNGISPFVKFSHFTANQAIQEAFEXEDRVHIVDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSMEAXEATGKRLSDFADKLGLPFEFFPVAEKVGNLDPERLNISKREAVAVHWLQHSLYDITGSDSNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYSEESEERHVVEQQLLSREIRNVLAVGGPSRSGEVKFHNWREKF-QQSGFXGISLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAW 815          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-------PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            K DE GL L+TLL +CA A+S DN  EA ++LLE+S++++P+G S A+RV AYF++AM++R+++S LGI +       P  + + + SAFQVFN ISPF+KF+HFT+NQAI EAF R DRVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+ ++D   + + + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +   + GF  + ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW
Sbjct:  443 KRDEEGLHLLTLLLKCAEAVSADNFDEATKILLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYASLPRSSVPTTHTQKMVSAFQVFNGISPFVKFSHFTANQAIQEAFEREDRVHIVDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSMEALEATGKRLSDFADKLGLPFEFFPVAEKVANLDPERLNISKREAVAVHWLQHSLYDVTGSDSSTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEVKFHNWREKF-QQTGFRGISLAGNAANQAALLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAW 810          

Query:  421 DEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY-------KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            +  GL L+ LL +CA  +++D+L +A  +L E+++++SP+G S  ERV AYF+ A+ +RVI+S LG  SPL N        + I +A Q +N+ISP +KF+HFTSNQAI +A    D VH++DLDIMQGLQWP LFHILA+R +    +R+TG G+SSE L  TG++L++FA  LGL FEF P+  KIG I D S + +R  E   VHW+ H LYD TG D  T+RL+  L P+++T+ EQD+S SGSFL RFV +LHYYS +FD+L   L +D+  RH VE  LF  EI NILA+GGP R+GE K  +W  EL  R GF  V +  N  AQA L+L MF P  GY+LV+ +G ++LGWKD SL  ASAW
Sbjct:  238 ESDGLRLLGLLLQCAEFVAMDSLDDASDLLPEIAELSSPFGSS-PERVGAYFSHALQTRVISSCLGTYSPLTNRTLTLAQSQRIFNALQSYNSISPLVKFSHFTSNQAIFQALDGEDHVHVIDLDIMQGLQWPGLFHILASRSKKIRSMRITGFGSSSELLESTGRRLADFASSLGLPFEFQPLEGKIGSITDLSQLGIRPSEATVVHWMHHCLYDVTGSDLATLRLLGSLRPKLITIAEQDLSHSGSFLSRFVEALHYYSALFDALGDGLGADSLERHMVEQQLFGYEIRNILAVGGPKRTGEVKVERWGDEL-KRVGFGPVSLGGNPAAQASLLLGMF-PWKGYTLVEENGCLKLGWKDLSLLTASAW 604          

Query:  430 GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY-------KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            GL L+ LL +CA  +++D L +A  +L E+++++SP+G S  ER+ AYFA A+ +RV++S LG  SPL          + I +A Q +N+ISP +KF+HFTSNQAI +A    D +H++DLDIMQGLQWP LFHILA+R +    +R+TG G+SSE L  TG++L++FA  LGL FEF P+  KIG I + + + ++  E   +HW+ H LYD TG D   +RL+  L P+++T+ EQD+S SGSFL RFV +LHYYS +FD+L   L +D+  RH VE  LF  EI NILA+GGP R+GE K  +W  EL  R GF  V +  N  AQA L+L MF P  GY+LV+ +G ++LGWKD SL  ASAW
Sbjct:  274 GLRLLGLLLQCAECVAMDKLDDASDLLPEIAELSSPFGSS-PERIGAYFAHALQTRVVSSCLGTYSPLTTKTLTLAQSQRIFNALQSYNSISPLVKFSHFTSNQAIFQALDGEDHIHVIDLDIMQGLQWPGLFHILASRTKKIRSMRITGFGSSSELLESTGRRLADFASSLGLPFEFQPLEGKIGSITELNQLGIKPSEATVIHWMHHCLYDVTGSDLAALRLLGSLRPKLITIAEQDLSHSGSFLGRFVEALHYYSALFDALGDGLGADSLERHMVEQQLFGCEIRNILAVGGPKRTGEVKLERWGDEL-KRVGFRGVSLGGNPAAQASLLLGMF-PWKGYTLVEENGCLKLGWKDLSLLTASAW 637          

Query:  430 GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY-------KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            GL L+ LL +CA  +++D L +A  +L E+++++SP+G S  ER+ AYFA A+ +RV++S LG  SPL          + I +A Q +N+ISP +KF+HFTSNQAI +A    D +H++DLDIMQGLQWP LFHILA+R +    +R+TG G+SSE L  TG++L++FA  LGL FEF P+  KIG I + + + ++  E   +HW+ H LYD TG D   +RL+  L P+++T+ EQD+S SGSFL RFV +LHYYS +FD+L   L +D+  RH VE  LF  EI NILA+GGP R+GE K  +W  EL  R GF  V +  N  AQA L+L MF P  GY+LV+ +G ++LGWKD SL  ASAW
Sbjct:  274 GLRLLGLLLQCAECVAMDKLDDASDLLPEIAELSSPFGSS-PERIGAYFAHALQTRVVSSCLGTYSPLTTKTLTLAQSQRIFNALQSYNSISPLVKFSHFTSNQAIFQALDGEDHIHVIDLDIMQGLQWPGLFHILASRTKKIRSMRITGFGSSSELLESTGRRLADFASSLGLPFEFQPLEGKIGSITELNQLGIKPSEATVIHWMHHCLYDVTGSDLAALRLLGSLRPKLITIAEQDLSHSGSFLGRFVEALHYYSALFDALGDGLGADSLERHMVEQQLFGCEIRNILAVGGPKRTGEVKLERWGDEL-KRVGFRGVSLGGNPAAQASLLLGMF-PWKGYTLVEENGCLKLGWKDLSLLTASAW 637          

Query:  322 QRSYGDHDHELQWGNELQLHADNNIRARGMSKLDEH--GLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVI-----NSWLGICSPLV----NYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARS-GEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTC 1512
            Q+    H H+ Q   +  LH +    A  M+   E   GL L+ LL  CA A++ ++   A R L  L+++ +P G S  +RV + F  A+++R+      N       P      N   I   +Q+     P+IKFAHFT+NQAI EAF   +RVH++DLDI+QG QWPA    LA R  G P +R+TGVG   E + ETG+ L+  A  L + FEFH +  ++ D+   M   R GE LAV+ +              + +I + AP IVTLVEQ+ S +G  FL RF+ +LHYYS +FDSL++  P D+  R  VE  +F  EI NI+A  G  R+   ++  +WR  +  + GF  V +SAN++ Q++++L ++    GY + + +G + LGW+D S+  ASAW C
Sbjct:  292 QQPQKQHHHQPQ--QQQNLHYNMMAPAIPMAHEQEQDSGLQLLHLLLVCAEAVAKEDYMLARRYLHHLNRVVTPLGDSM-QRVASCFTDALSARLAATLTTNPRASAPQPFSPFPPNSLEILKIYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDILQGYQWPAFMQALAARPSGAPFLRITGVGPCIEAVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLHRVPVNXLGNLLAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGAERTERHERLEKWRKVMESK-GFKSVALSANAVTQSKILLGLY-SCDGYRMTEDNGCLLLGWQDRSIMAASAWRC 696          

Query:  346 HELQWGNELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLV---------NYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGS-FLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARS-GEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTC 1512
            H+ Q   +  LH  N +      +  + GL L+ LL  CA A++ ++   A R L  L+++ +P G S  +RV + F +A+++R+  +     S            N   I   +Q+     P+IKFAHFT+NQAI EAF   +RVH++DLDI+QG QWPA    LA R  G P +R+TGVG   E + ETG+ L+  A  L + FEFH +  ++ D+   M   R GE LAV+ +      +       + +I + AP IVTLVEQ+ S +G  FL RF+ +LHYYS +FDSL++  P D+  R  VE  +F  EI NI+A  G  R+   ++  +WR  +  + GF  V +SAN++ Q++++L ++    GY + +  G + LGW+D S+  ASAW C
Sbjct: 1169 HQHQHQQQQNLHY-NMMPPMAHEQEQDSGLQLVHLLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSM-QRVASCFTEALSARLAATLTTTPSXSASKPFSPFPPNSFEILKIYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDILQGYQWPAFMQALAARPGGAPFLRITGVGPCIEGVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLHRVSVNCLGNLLAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGVERTERHERLEKWRKVMESK-GFKSVPLSANAVTQSKILLGLY-SCDGYRMTEDKGCLLLGWQDRSIMAASAWRC 1564          

Query:  412 SKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSW---LGICSPLVNYKSIHSA---FQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVH---WLQHSLYDATGPDWKT-MRLIEELAPRIVTLVEQDMSQSGSFLD-RFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPAR-SGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGD-----GTIRLGWKDTSLYVASAWT 1509
            S+ +  G  L++LL  C  AI + N+   +  + +L ++ASP G S   R  AY+ +A++ RV   W     I +P    +    +    ++ N +SP  KF HFTSN+ +L AF  +DRVHI+D DI QGLQWP+LF  L +R   P  VR+TG+G S + L ETG +L+ FA  L L FEFHP+V ++ D+   M+ V+  E++AV+    L  +LYD TG   +  + LI    P +V + EQ+   + S L+ R   SL YYS +FDS+ S LP ++ +R  VE  +F +EI NI+A  G  R    + F +WR +L  + GF  VG++   M Q+Q +L M+  +  Y++ + +       + L W D  LY  SAWT
Sbjct:  289 SEAEHLGFELVSLLTACVEAIGLKNIAAINHFIAKLGELASPKG-SAISRXSAYYTEALSLRVTRLWPHVFQINAPRKFDRRDEDSGIELRLLNQVSPIPKFVHFTSNEILLRAFEGKDRVHIIDFDIKQGLQWPSLFQSLVSRTNPPSHVRITGIGESKQELNETGDRLAGFAGALNLPFEFHPVVDRLEDVRLWMLHVKEHESVAVNCVFQLHKTLYDTTGGALRDFLGLIRSTNPTLVLMAEQEAEHNESKLETRVSNSLKYYSAIFDSIGSSLPLESQARIKVEE-MFAQEIRNIIACEGSDRLERHESFEKWR-KLMEQEGFRCVGITEREMLQSQFLLKMY-ASENYTVKKQEKNGAAEALTLSWMDQPLYTVSAWT 667          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSE--DYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADN------NIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +E+ HG +NMIQ HE W +Y S  VGF   P SNPFP P  IENR + LER+ELS+WVEH+TKQLI                   +      + SSL  +   P K  +RSY D +  ELQW +EL +H  N      + R+  MS++DE+GLSLITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPSCAERVVAYF+KAM SRVINSWLGICSPL+N+KSIH AFQVFN  SPFIKFAHFTSNQ+ILEAFHRRDRVH++DLDIMQGLQWPALFHILATR++GPPQVRMTG+GTS E L+ETG+QLSNFAKRLG+SFEFHPI +K G+IDASMV +RRGET+AVHWLQH+LYDATGPDWKT+RL+E + PR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YLP D+P RH +EHCL YREINNILAIGGPARSGEDKFRQWRSEL  R+ FMQV MS NSMAQAQLILNMFPP HGY+L QG+GT+RLGWKDTSL+ ASAWT + ASR
Sbjct:    5 YEVVHGALNMIQPHETW-DYAS--VGFPA-PISNPFPKPAVIENRCLNLERNELSEWVEHVTKQLIDDLPDIATDHDESLQTDTTTVYGGNDIVSSLLGEF-RPKKYMRRSYFDGNGEELQWSHELGVHQTNISEKEGSTRSPSMSRIDENGLSLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSCAERVVAYFSKAMGSRVINSWLGICSPLINHKSIHGAFQVFNNASPFIKFAHFTSNQSILEAFHRRDRVHVIDLDIMQGLQWPALFHILATRIDGPPQVRMTGMGTSMELLLETGRQLSNFAKRLGMSFEFHPIAKKFGEIDASMVPLRRGETVAVHWLQHTLYDATGPDWKTLRLLEAVGPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLPCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRQWRSEL-ARSSFMQVPMSGNSMAQAQLILNMFPPAHGYNLEQGEGTLRLGWKDTSLFTASAWT-TRASR 514          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGD-HDHELQWGNELQLHADNNIRARG-----MSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +EMAHG +++IQ HEPW +  S   GF   P SNPFP P  IENR V LER+ELS+WVEH+TKQLI                     D  +  SL  D   P K  +RSY D +  ELQW +EL  H  +     G     MS++DE+GL+LITLL ECAVAISVDNL EAHRMLLEL+QMASPYGPS AERVVAYF+KAM SRVINSWLGICSPL+N+KS+HSAFQVFN +SPFIKFAHFTSNQAILEAF RRD VHI+DLDIMQGLQWPALFHILATR+EGPPQVRMTG+G+S E L+ETGKQLSNFA+RLGL FEFHPI +K G+ID SMV +RRGETLAVHWLQHSLYDATGPDWKT+RL+E LAPR++TLVEQD+S  GSFLDRFVGSLHYYST+FDSL +YL  D+P RH +EHCL YREINNILAIGGPARSGEDKFR WRSEL  +N FMQV MS NSMAQAQLILNMFPP HGY+LVQGDGT+RLGWKDTSL+ ASAWT S ASR
Sbjct:    5 YEMAHGALDLIQPHEPWDHCAS--AGFPA-PISNPFPKPV-IENRCVNLERNELSEWVEHVTKQLIDDVPDTETHDSLQTDTRMVYGDNNIVPSLLGDHFRPKKSMRRSYFDGNGEELQWSHELGEHQASISEKEGSARSSMSRIDENGLNLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGPSSAERVVAYFSKAMGSRVINSWLGICSPLINHKSVHSAFQVFNNVSPFIKFAHFTSNQAILEAFQRRDSVHIIDLDIMQGLQWPALFHILATRIEGPPQVRMTGMGSSMEVLVETGKQLSNFARRLGLPFEFHPIAKKFGEIDVSMVPLRRGETLAVHWLQHSLYDATGPDWKTLRLLEALAPRVITLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAYLHCDDPGRHRIEHCLLYREINNILAIGGPARSGEDKFRHWRSEL-AKNSFMQVAMSGNSMAQAQLILNMFPPAHGYNLVQGDGTLRLGWKDTSLFTASAWT-SRASR 512          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXX-----SEDYFVPSSLSTDLITPSKISQRSYGD-----HDHELQW-----GNELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRN-GFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            +E+ +G ++M+Q+HE W +Y S V GFQ    SN FP     +     LER+ELS+WVEH+T+QLI                        S +  VPS L++D   P K  +RS+ D     H+ ELQW     GN+++++ +     RG+S++DEHGL+LI+LLFECAVAISVDNL EAHRMLLEL+QMASPYGPSCAERVVAYFAKAM SRVINSWLGICSPL+N+K++HSAFQVFN +SPFIKFAHF SNQ ILEAF RRDRVHI+DLDIMQGLQWPALFHILATRMEGPP +RMTG+GTS + L+ETGKQLSNFAKRLGLSFEFHPI +K G+ID SMV +RRGETLAVHWLQHSLYDATGPDWKTMRL+EEL+PRI+TLVEQD+S  GSFLDRFVGSLHYYST+FDSL ++LP D+ SRH VEHCL YREINN+LAIGGPARSGEDK R WRSEL  R+  FMQV MS NSMAQAQLILNMFPP HGYSL QG+G +RLGWKDTSL+ ASAWT S ASR
Sbjct:    5 YEVVNGAIDMMQTHEAW-DYGSSV-GFQAAAASNSFP-----KQVVTNLERNELSEWVEHVTRQLIDDMPDTPSDHSLQTDTAMVCNEDSSNNNVVPSLLTSDS-RPRKALKRSHFDGAYSIHEEELQWSNIELGNQIRINENGASNGRGLSRIDEHGLNLISLLFECAVAISVDNLGEAHRMLLELTQMASPYGPSCAERVVAYFAKAMASRVINSWLGICSPLINHKTVHSAFQVFNNVSPFIKFAHFISNQEILEAFQRRDRVHIIDLDIMQGLQWPALFHILATRMEGPPHIRMTGMGTSMDLLVETGKQLSNFAKRLGLSFEFHPIAKKFGEIDVSMVPLRRGETLAVHWLQHSLYDATGPDWKTMRLLEELSPRIMTLVEQDISHGGSFLDRFVGSLHYYSTLFDSLGAFLPCDDSSRHRVEHCLLYREINNVLAIGGPARSGEDKLRHWRSELAARSTSFMQVPMSGNSMAQAQLILNMFPPAHGYSLAQGEGALRLGWKDTSLFTASAWT-SLASR 519          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRAR----GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHASR 1527
            FE+ HG +++IQ HE W      ++G Q   +SN FP P  +ENR   LER+ELS+WVEH+TKQLI                        V   L T+ +T         G     LQWGNE      NN+       G+S+LDEHGL LITLL ECAVAISVDNL EAHRMLLEL+QMASPYG SCAERVV+YFAKAM SRVINSWLG+CSPL+++K++HS+ Q+FN ISPFIKFAHFTSNQ+ILEAFHRRD VHI+DLDIMQGLQWPALFHILATR+EGPP +RMTG+G+S E L +TGKQLSNFA+RLGLSFEFHP+ +K G+I D + +Q+RRGETLAVHWLQHSLYDATGPDWKT+RL+EELAPR++TLVEQ++S  GSFLDRFVGSLHYYST+FDSL +  PSD+P RH VEHCL YREINNI+AIGGPARSGEDKFRQWRSE+  RN F+QV MS N+MAQAQLILNMFPP HGYSLV+G+GT+RLGWKDT LY ASAWT SHA R
Sbjct:    5 FEVVHGALDLIQPHEQWEYN---IIGLQGASSSN-FPKPMVVENRS-NLERNELSEWVEHVTKQLIEDLPET------------------VGEGLKTEEVTIVG------GSFAPVLQWGNEAAGSQSNNLSTGDINGGLSRLDEHGLGLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGASCAERVVSYFAKAMASRVINSWLGLCSPLISHKAVHSSLQIFNNISPFIKFAHFTSNQSILEAFHRRDLVHIIDLDIMQGLQWPALFHILATRIEGPPHIRMTGMGSSIELLTQTGKQLSNFARRLGLSFEFHPVAKKFGEINDITSLQIRRGETLAVHWLQHSLYDATGPDWKTIRLLEELAPRVITLVEQEISHGGSFLDRFVGSLHYYSTIFDSLGASFPSDDPGRHRVEHCLLYREINNIMAIGGPARSGEDKFRQWRSEMAARNCFVQVPMSGNAMAQAQLILNMFPPAHGYSLVKGEGTLRLGWKDTGLYSASAWT-SHAYR 487          

Query:    4 FEMAHGTMNMIQSHEPWTNYPSPVVGFQNNPTSNPFPIPKPIENRFVTLERSELSQWVEHITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRAR----GMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDI-DASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWT 1509
            FE+ HG +++IQ HE W      ++G Q   +SN FP P  +ENR   LER+ELS+WVEH+TKQLI                        V   L T+ +T         G     LQWGNE      NN+       G+S+ DEHGL LITLL ECAVAISVDNL EAHRMLLEL+QMASPYG SCAERVV+YFAKAM SRVINSWLG+CSPL+++K++HS+ Q+FN ISPFIKFAHFTSNQ+ILEAFHRRD VHI+DLDIMQGLQWPALFHILATR+EGPP +RMTG+G+S E L +TGKQLSNFA+RLGLSFEFHP+ +K G+I D + +Q+RRGETLAVHWLQHSLYDATGPDWKT+RL+EELAPR++TLVEQ++S  GSFLDRFVGSLHYYST+FDSL +  PSD+P RH VEHCL YREINNI+AIGGPARSGEDKFRQWRSE+  RN F+QV MS N+MAQAQLILNMFPP HGYSLVQG+GT+RLGWKDT LY ASAWT
Sbjct:    5 FEVVHGALDLIQPHEQWEYN---IIGLQGASSSN-FPKPMVVENRS-NLERNELSEWVEHVTKQLIEDLPET------------------VGEGLKTEEVTIVG------GSFAPVLQWGNEAAGSQSNNLSTGDINGGLSRPDEHGLGLITLLLECAVAISVDNLGEAHRMLLELTQMASPYGASCAERVVSYFAKAMASRVINSWLGLCSPLISHKAVHSSLQIFNNISPFIKFAHFTSNQSILEAFHRRDMVHIIDLDIMQGLQWPALFHILATRIEGPPHIRMTGMGSSIELLTQTGKQLSNFARRLGLSFEFHPVAKKFGEINDITSLQIRRGETLAVHWLQHSLYDATGPDWKTIRLLEELAPRVITLVEQEISHGGSFLDRFVGSLHYYSTIFDSLGASFPSDDPGRHRVEHCLLYREINNIMAIGGPARSGEDKFRQWRSEMAARNCFVQVPMSGNAMAQAQLILNMFPPAHGYSLVQGEGTLRLGWKDTGLYSASAWT 482          

Query:   43 HEPWTNYPSPVVG--FQNNPTSNPFPIPKPIENRFVTLERSELSQWVEH----ITKQLIXXXXXXXXXXXXXXXXXXXSEDYF---VPSSLSTDLITPSKISQRSYGDHDHELQWGNELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            HE W +Y + +    F     SNP+P P    N  + L ++EL  W+E     ITK  +                      +    VPS LS +         R   +          L +  + +   +    + + GL+LITLL ECAVAISVDNL EAHRMLLEL+QMASPY  SCAERVVAYFAKAMTSRV+NSWLG+CSPLV++KSI+SAFQVFN ISPFIKFAHFTSNQAILEA    D +HI+DLDIMQGLQWPA FHILATRMEG P+V MTG+G S E L+ETGKQL+NFA+RLGLS +FHPI  K G+ ID SM+ V+ GE +AVHWLQHSLYDATGPDWKT+RL+EEL PRI+TLVEQD++  GSFLDRFV SLHYYST+FDSL +YL +D+ +RH VEH L  REINN+LAIGGP RSGED FRQWRSEL       QV +S NSMAQAQLILNMF P +GYSL Q +GT+RLGWKDTSLY ASAWTC ++S
Sbjct:    7 HETWDHYSNTITSLPFSAPTPSNPYPKPATENNHCLNLGQNELCDWMEEHISDITKHFVEDLPETTTSDNLLSNNPTGVVSHHNLGVPSLLSPNFTQRKPSCFRPQFESFTNDPPNFNLHIQTNTSTLDQNKHNVYDQGLNLITLLMECAVAISVDNLGEAHRMLLELTQMASPYKASCAERVVAYFAKAMTSRVMNSWLGVCSPLVDHKSINSAFQVFNNISPFIKFAHFTSNQAILEAVSHCDSIHIIDLDIMQGLQWPAFFHILATRMEGKPKVTMTGLGASMELLVETGKQLTNFARRLGLSLKFHPIATKFGEVIDVSMLHVKPGEAVAVHWLQHSLYDATGPDWKTLRLLEELEPRIITLVEQDVNHGGSFLDRFVASLHYYSTLFDSLGAYLHNDDSNRHRVEHGLLSREINNVLAIGGPKRSGEDNFRQWRSELARHCFVKQVPLSDNSMAQAQLILNMFSPAYGYSLAQVEGTLRLGWKDTSLYTASAWTCCNSS 510          

Query:   43 HEPWTNYPSPVVGFQ---NNPT--SNPFPIPKPIENRFVTL-ERSELSQWVEH----ITKQLIXXXXXXXXXXXXXXXXXXXSEDYFVPSSLSTDLITPSKISQR-----------SYGDHDHELQWGNELQLHADNNIRARGMSKLD---EHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGD-IDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQ--SGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            HE W ++ S  +      ++PT  SNP+P P    N  + + + +EL  W+E      TK L+                     +     +L+   +   K SQR           S+ ++D          LH   N      S+ +   + GLSLITLL ECAVAISVDNL EAHRMLLEL+Q++SPY  SCAERVVAYFAKAMTSRV+NSWLG+CSPLV++KSI+S+FQVFN ISPFIKFAHFTSNQAILEA    D +HI+DLDIMQGLQWPA FHILATRMEG PQV MTG G S E L+ETGKQL+NFA+RLG+S +F PI  KIG+ ID S + V+ GE +AVHWLQHSLYDATGPDWKT+RL+EEL PRI+TLVEQD++    GSFLDRFV SLHYYST+FDSL +YL +D+ +RH VEH L  REINN+L IGGP RS EDKFRQWR+EL       QV MSANSMAQAQLILNMF P +GYSL Q +GT+RLGWKDTSLY ASAWTCS++S
Sbjct:    7 HETWDDHYSNNITTSLPFSSPTTPSNPYPKPATENNHCLNMGQNNELCDWMEEQVSDFTKHLVEDFPETTTTSDNLLSNNPTRVNIASHHNLNVPSLLSPKFSQRKPSCLFRPQFESFTNNDPP-----NFNLHIQTNTSTLDQSQHNVVYDQGLSLITLLMECAVAISVDNLGEAHRMLLELTQVSSPYKASCAERVVAYFAKAMTSRVMNSWLGVCSPLVDHKSINSSFQVFNNISPFIKFAHFTSNQAILEAVSHCDSIHIIDLDIMQGLQWPAFFHILATRMEGKPQVTMTGFGASMELLVETGKQLTNFARRLGMSLKFLPIATKIGEVIDVSTLHVKPGEAVAVHWLQHSLYDATGPDWKTLRLLEELEPRIITLVEQDVNHGGGGSFLDRFVASLHYYSTLFDSLGAYLHNDDENRHRVEHGLLSREINNVLGIGGPKRS-EDKFRQWRNELARHCFVKQVPMSANSMAQAQLILNMFSPAYGYSLAQVEGTLRLGWKDTSLYTASAWTCSNSS 521          

Query:  415 KLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICS-----PLVNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            K DE GL L+TLL +CA A+S DN  EA++MLLE+SQ+++PYG S A+RV AYF++AM++R+INS LGI +     PL + + + SAFQVFN ISPF+KF+HFT+NQAI EAF R DRVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +L  ++GF  + ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   HA+
Sbjct:  446 KRDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISQLSTPYGTS-AQRVAAYFSEAMSARLINSCLGIYATLPSMPLTHTQKMASAFQVFNGISPFVKFSHFTANQAIQEAFEREDRVHIIDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSIEALEATGKRLSDFAQKLGLPFEFFPVADKVGNLDPDRLNVSKREAVAVHWLQHSLYDVTGSDSNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEVKFHNWREKL-RQSGFKGISLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHAT 817          

Query:  418 LDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPLVNY---KSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAWTCSHAS 1524
            LDE GL L+TLL +CA A+S DN  EA++MLLE+S++++P+G S A+RV AYF++AM++R+++S LGI + L      + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+L++FA++LGL FEF P+  K+G++D   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL +    ++  RH VE  L  REI N+LA+GGP+RSG+ KF  WR +L  ++GF  V ++ N+  QA L+L MF P+ GY+LV+ +GT++LGWKD  L  ASAW   HA+
Sbjct:  285 LDEEGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTS-AQRVAAYFSEAMSARLVSSCLGIYATLPTVPHSQKLVSAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGLQWPGLFHILASRPGGPPFVRLTGLGTSMEALEATGKRLTDFAEKLGLPFEFFPVAEKVGNLDPERLNVSKREAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSFLGRFVEAIHYYSALFDSLGASYGEESEQRHAVEQQLLSREIRNVLAVGGPSRSGDVKFNNWREKL-QQSGFRVVSLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWRPFHAA 653          

Query:  367 ELQLHADNNIRARGMSKLDEHGLSLITLLFECAVAISVDNLPEAHRMLLELSQMASPYGPSCAERVVAYFAKAMTSRVINSWLGICSPL----VNYKSIHSAFQVFNTISPFIKFAHFTSNQAILEAFHRRDRVHILDLDIMQGLQWPALFHILATRMEGPPQVRMTGVGTSSENLMETGKQLSNFAKRLGLSFEFHPIVRKIGDIDASMVQVRRGETLAVHWLQHSLYDATGPDWKTMRLIEELAPRIVTLVEQDMSQSGSFLDRFVGSLHYYSTMFDSLESYLPSDNPSRHNVEHCLFYREINNILAIGGPARSGEDKFRQWRSELGGRNGFMQVGMSANSMAQAQLILNMFPPTHGYSLVQGDGTIRLGWKDTSLYVASAW 1506
            EL +        +   K DE GL L+TLL +CA A+S +NL +A++MLLE+SQ+++P+G S A+RV AYF++A+++R+++S LGI + L    ++ + + SAFQVFN ISPF+KF+HFT+NQAI EAF R +RVHI+DLDIMQGLQWP LFHILA+R  GPP VR+TG+GTS E L  TGK+LS+FA +LGL FEF P+  K+G+ID   + V + E +AVHWLQHSLYD TG D  T+ L++ LAP++VT+VEQD+S +GSFL RFV ++HYYS +FDSL S    ++  RH VE  L  REI N+LA+GGP+RSGE KF  WR +L  + GF  + ++ N+  QA L+L MF P+ GY+LV+ +G ++LGWKD  L  ASAW
Sbjct:  411 ELAITRKKKEEIKEQKKKDEEGLHLLTLLLQCAEAVSAENLEQANKMLLEISQLSTPFGTS-AQRVAAYFSEAISARLVSSCLGIYATLPPHTLHNQKVASAFQVFNGISPFVKFSHFTANQAIQEAFDREERVHIIDLDIMQGLQWPGLFHILASRPGGPPYVRLTGLGTSMETLEATGKRLSDFASKLGLPFEFFPVAEKVGNIDVEKLNVSKSEAVAVHWLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSNAGSFLGRFVEAIHYYSALFDSLGSSYGEESEERHVVEQQLLSREIRNVLAVGGPSRSGEIKFHNWREKL-QQCGFRGISLAGNAATQASLLLGMF-PSEGYTLVEDNGILKLGWKDLCLLTASAW 791