ppa016418m, ppa016418m (mRNA) Prunus persica

Query:   22 SHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S SA + YS  Y+P+ + G+A+   F Y DE+ NHKRLKRT SIAES+ S++SLY GG + S  ++  I+RS STNSLN+LPRLHFRDHIWTYTQRYL                      DG+ DGMRLVQLLIACAEAVACRDK+HAS+LLSELRANALVFGSSFQRVASCFVQGLA+RL+LVQPLGAVGFI   +N  D A +KKEEALRLVYEICPHI+FGHFVAN+SILEAFEGE++ HVVDLGMTLGL HG QWR LI SLA RAG+PP RLRITGVGL  DR +IIG+ELEAYA  L INL+                            ILQLHCVVKESRGALNSVLQ ++ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSL+AMLPKYDTRRAK+EQFYF EEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  AKQWLGK+  CEGY I+EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   20 SLSAQAYYSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIAESIGSNSSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWEKKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLD----------------------------ILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWKC 491          

Query:  400 MRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            M+LV  LI CA+ VA RDKSHASALLSELRANALVFG+SFQRVASCFVQGL++RL+L+Q LGAVG  G  +   D    +KEEA RL +EICP IQFGH  AN+SILEAFEGES VHVVDLGM LG P G QWR L+ SLA RAG+PPS L+ITGVG   + ++ I DELE YA+ LG+N +FS+                            LHCVVKESRGALNSVLQ + ELSPK +VLVEQD+SHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEG ARVERH+R+DQWRRRMSRAGFQ++P+KM+  AKQWL K+ +C+GYTI++EKGCLVLGWKSKPI+AASCWKC
Sbjct:    1 MKLVHQLITCAKVVAFRDKSHASALLSELRANALVFGTSFQRVASCFVQGLSDRLSLIQSLGAVGVGGCTVKTMDIT-PEKEEAFRLFFEICPQIQFGHLAANASILEAFEGESSVHVVDLGMNLGSPQGQQWRSLMHSLANRAGKPPSSLQITGVGTAAECLKDIIDELEVYAESLGMNFQFSM----------------------------LHCVVKESRGALNSVLQKIRELSPKAVVLVEQDASHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGSARVERHQRLDQWRRRMSRAGFQSSPMKMITEAKQWLEKVKLCDGYTIVDEKGCLVLGWKSKPIIAASCWKC 346          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKE--EALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            G++LV  L+ACAEAVA  D   A   L  L       G S QRVASCF + L+ RLA             P N   F  +  E  +  +++Y+ CP+I+F HF AN +I EAFE E  VHV+DL +  G     QW   I++LA R G  P  LRITGVG   + ++  G  L   A  L +  EF  V   LE+L+P       GE L VNS  +LH V       L ++L M+ + +P I+ +VEQ++SHNGP+FLGRF+EALHYYSAIFDSLDA  P    +RAK+EQ+ FA  I+NI++CEG  RV RHER+++WR+ M   GFQ  P+    +  +K  LG +  C+GY + E+KGCL+LGW+ + I+AAS W+C
Sbjct:  300 GLQLVHFLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLTPKPSTSTTKPFNP--FPPNSLEILKIYQILYQACPYIKFAHFTANQAIFEAFEAEERVHVIDLDILQGY----QWPAFIQALAARPGGAPF-LRITGVGCSPESVRETGRCLTELAHSLHVPFEFHPVGEELEDLKPHMFNRRVGEALAVNSANRLHRV---PTNFLGNLLAMIRDQAPNIVTIVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKLEQYIFAPVIRNIVACEGAERVMRHERLEKWRKLMEGKGFQGVPLSANAVTQSKILLG-LYSCDGYRLTEDKGCLLLGWQDRAILAASAWRC 668          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCV-------VKESRGA-----------LNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKM--LVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G+ L++LL+ACA  VA     +A+  L  +   A   G + QR+A+ F + LA+R+    P    G   +  + K  ++ ++    +L +E+CP ++  + + N +I+EA EGE  VH++DL          QW  L++SL+ R   PP  LRITG+    + + ++  +L   A++L I  +F+ + S LENL  E +++  GE L ++S+LQLH +       V +S  A           + S L  +  LSPK++V+ EQ+S++N P  + R MEAL++Y+A+FD L++ L +    R K+E+  F EEIKNII+CEGP R ERHE++++W  R+  AGF   P+    ++ A + L      +GY + EE GCLV+ W+ +P+ + S W+
Sbjct:   46 GLYLIRLLVACANHVAAGSIENANIGLEHISHLASPDGDTVQRIAAYFTEALADRMLKGWP----GLHKALNSTKISSISEEILVQKLFFELCPFLKLSYVITNQAIIEAMEGEKMVHIIDLNSF----ESAQWINLLQSLSARPEGPP-HLRITGIHEQKEVLDLMALQLTKEAEKLDIPFQFNPIVSKLENLDFESLRVKTGEALAISSVLQLHTLLAIDDEMVGKSPSASKNTSAVHLQRMGSFLAALWGLSPKLMVVTEQESNNNCPTLMERVMEALNFYAALFDCLESTLSRASIERQKVEKMLFGEEIKNIIACEGPERKERHEKLEKWVMRLELAGFGRVPLSYQGMLQASRLLVSYGY-DGYRMKEENGCLVICWQDRPLFSVSAWR 430          

Query:  406 LVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVG------LYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCW 1518
            L ++L++CA+AVA  D   A   +SELR    V G   QR+ +  ++GL  RLA      +   I   +  K+ A  +    + L++EICP+ +FGH   N +I EA + ES VH++D  ++ G+    QW  LI++LA R G PP ++RITG+         G    I+G  L  +A+   +  EF     +   ++ ED++L  GE L VN    LH +  ES    N    +L++V  LSPK++ LVEQ+S+ N   FL RF+EA++YY A+F+S+D  LP+    R   EQ   A EI NII+CEG  RVERHE + +W+ R   AGF   P+   VNA       N  + Y++ E+ G L LGW  + +VAA  W
Sbjct:  156 LKEVLVSCAKAVADNDILRAEWGISELRQMVSVSGEPIQRLGAYMLEGLVARLA-----ASGSSIYKALRCKEPASAELLSYMHLLFEICPYFKFGHMSGNGAIAEAMKDESKVHIIDFQISQGV----QWITLIQALAARPGGPP-QIRITGIDDSTSAYARGGGPSIVGQRLSRFAESCKVPFEFHAATISGCEVQLEDLELRPGEALAVNFAFILHHMPDESVDTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAPFLSRFIEAMNYYLAVFESIDVTLPRDHKERINAEQHCLAREIVNIIACEGAERVERHELLGKWKSRFLMAGFTPHPLSSYVNATIKTLLQNYSDKYSLEEKDGALYLGWMDRALVAACAW 525          

Query:  463 ASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVG------LYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            A  L+ ELR    V G   QR+ +  ++GL  RLA      +   I   +  K+ A       + ++YE+CP+ +FG+  AN +I EA + E+ VH++D      +  G QW  LI++ + R G PP  +RITG+         G  + I+G  L   A+ + +  EF   + +   ++ E++    GE L VN    LH +  ES    N    +L++V  LSPK++ LVEQ+S+ N   F  RF+E L+YY+A+F+S+D  LP+   +R  +EQ   A ++ NII+CEG  RVERHE + +WR R + AGF   P+  LVNA       N  + Y + E +G L LGW  + +VA+  WK
Sbjct:  133 AQWLMDELRQMVSVSGEPIQRLGAYMLEGLVARLA-----SSGSSIYKALRCKEPASADLLSYMHILYEVCPYFKFGYMSANGAIAEAMKDENRVHIIDFQ----IGQGSQWITLIQAFSARPGGPP-HIRITGIDDSTSAYARGGGLNIVGQRLSRLAESVKVPFEFHAADMSGCEVQLENLGARPGEALAVNFAFMLHHMPDESVSTQNHRDRLLRLVKSLSPKVVTLVEQESNTNTAAFFPRFLETLNYYTAMFESIDVTLPREHKKRISVEQHCLARDVVNIIACEGVERVERHELLGKWRLRFAMAGFTPYPLSSLVNATIKRLLENYSDKYRLEEREGALYLGWMDRDLVASCAWK 484          

Query:  394 DGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            +G+ L+ LL+ CAEAV+  +   A+ +L E+   +  FG+S QRVA+ F + ++ RL +   LG    + +  +++     K   A ++   I P ++F HF AN +I EAFE E  VH++DL +  GL    QW GL   LA+R G PP  +R+TG+G   + ++  G  L  +A++LG+  EF  V   + NL PE + +   E + V+    L   + +  G+  + L ++  L+PK++ +VEQD SH G F LGRF+EA+HYYSA+FDSL A   +   +R  +EQ   + EI+N+++  GP+R     + + WR ++ ++GF+   +       A   LG     +GYT++E+ G L LGWK   ++ AS W+
Sbjct:  288 EGLHLLTLLLQCAEAVSADNFEEANKMLLEISELSTPFGTSAQRVAAYFSEAMSARL-VSSCLGIYATLPTVPHSQ-----KLVSAFQVFNGISPFVKFSHFTANQAIQEAFEREERVHIIDLDIMQGL----QWPGLFHILASRPGGPPF-VRLTGLGTSMEALEATGKRLTDFAEKLGLPFEFFPVAEKVGNLDPERLNVSKREAVAVH---WLQHSLYDVTGSDTNTLWLLQRLAPKVVTVVEQDLSHAGSF-LGRFVEAIHYYSALFDSLGASYGEESEQRHAVEQQLLSREIRNVLAVGGPSR-SGDVKFNNWREKLQQSGFRVVSLAGNAATQATLLLGMF-PSDGYTLVEDNGTLKLGWKDLCLLTASAWR 648          

Query:  400 MRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLA-LVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQ--PPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVV-----ESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIK--MLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCW 1518
            +++ QLLI+CAE V+  D S A  LLS L +N+  FG S +R+   F   L+ RL+    P  + G + +  N      +        + +I P I+F    AN +ILEA EG+  +H++D  +     HG QW  L++++A R G   PP  +RITG G     +Q  GD L  +A  LG+  +F  +      +++    P  ++LL  E L VN +L LH ++K+    L   L  +  + PK++ + E++++HN P FL RF+EAL +Y+A+FDSL+A LP     R  +E+ +F  EI +I+S EG  R ERHER + W   +  +GF   P+    L  AK  L      EGY +        LGW+++ + + S W
Sbjct:   34 IQMRQLLISCAELVSQSDFSAARRLLSILSSNSSPFGDSTERLVHQFSAALSLRLSRYATPATSSGAMSASANTAAADSEAFHSTYLSLNQITPFIRFSQLTANQAILEAIEGQRAIHILDFDIM----HGVQWPPLMQAIAERCGNLHPPPMIRITGTGEDLGILQRTGDRLLKFAQSLGLKFQFHPLLLRNDPTSVPLYLPSALQLLPDETLAVNCVLYLHRLLKDDSRDLRLFLHKIKAMEPKVVTIAEREANHNHPLFLQRFVEALDHYTAVFDSLEATLPPTSRERLAVERIWFGREIVDIVSAEGDNRRERHERFESWEVMLRSSGFSNVPLSPFALSQAKLLLRLHYPSEGYRLQIINDSFFLGWQNQALFSVSSW 412          

Query:  415 LLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLY------GDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGAL-NSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAK-QWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            LLI CA+AVA  ++  A+ +L  +R ++  FG+  QR+A  F   L  RLA     G    + + +  K  ++    +A +L    CP  +  +  AN  I +  EG + +H++D G+  G     QW  LI+ L+ R G PP +LRITG+          +R++  G  L  Y  R  +  E+  +    E ++ ED+++                   +  G L ++VL+++  ++P I +    + + N PFF  RF EAL ++ A+FD LDA +P+ D  R   E+  + ++I NII+CEG  R+ER +   QW+ R  RAG +  P++  +  K + + K++  + + +  + G ++ GWK + I A SCWK
Sbjct:  148 LLIQCAQAVAAYNQRAANDILKLIRQHSSPFGNGSQRLAHFFANSLEARLA-----GTGLQMYTALATKRTSVADVIKAYQLYVSACPFKRMSNRYANRVIAKLAEGATRLHIIDFGVLYGF----QWPCLIQFLSLRPGGPP-KLRITGIDFPQPGFRPAERVEETGRRLANYCKRFKVPFEYKAIAQRWETIKVEDLEI-------------------DRDGCLKDAVLELIRRINPDIFIHGVLNGNFNTPFFFTRFREALFHFDALFDMLDASVPREDEGRMMFEREIYGKDIMNIIACEGSERIERPDIYKQWQARNERAGLRQLPLEQEILMKVRNIVKMDYHKDFVVEVDGGWMLHGWKGRVIYAISCWK 495          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVF---GSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEE----ALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPS-RLRITGVGLYG------DRMQIIGDELEAYADRLGINLEFSVVE-SNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGP-FFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVER---HERVDQWRRRMSRAGFQAAPIKML--VNAKQWLGKINVCEGYTILE-EKGCLVLGWKSKPIVAASCW 1518
            G+RLV LL+A AEA+   +KS   A +  +R   LV    G++ +R+A+ F   L     L++  GA   IG+  +  D      +     A +L+ ++ P+++FGHF AN +ILEA   E  +H+VD  +  G+    QW  L+++L +R   PP+  LRIT +   G        +Q  G  L A+A  +G    F      + E  RP  +KL+ GE L++N +L L      +  ++ S L     L PK++ LVE++    G   F+GRFM++LH+YSA++DSL+A  P     RA +E+ +    I   +      R+ R    +    W   +  AGF+   I       AK  LG  N  +GY + E     +VLGWKS+   +  CW
Sbjct:  100 GLRLVHLLMAAAEALTGVNKSRDLARVILVRLKELVSPTDGTNMERLAAYFTDALQG---LLEGAGAKHMIGNGHHRDDHHHHHHQSDVLAAFQLLQDMSPYVKFGHFTANQAILEAVSKERRIHIVDYDIMEGI----QWASLMQALVSRKDGPPAPHLRITALSRGGGGRRSIGTIQETGRRLTAFAASIGQPFSFHQCRLDSDETFRPSALKLVRGEALIINCMLHLPHFSYRAPDSVASFLSGGKTLKPKLVTLVEEEVGPTGDGGFVGRFMDSLHHYSAVYDSLEAGFPMQGRARALVERVFLGPRIAGTL-----GRIYRGRGGQEGGSWGEWLDGAGFRGVGISFANHCQAKLLLGLFN--DGYRVEELANNRMVLGWKSRR--STYCW 479          

Query:   22 SHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S SA + YS  Y+P+ + G+A+   F Y DE+ NHKRLKRT SIAES+ S++SLY GG + S  ++  I+RS STNSLN+LPRLHFRDHIWTYTQRYL                      DG+ DGMRLVQLLIACAEAVACRDK+HAS+LLSELRANALVFGSSFQRVASCFVQGLA+RL+LVQPLGAVGFI   +N  D A +KKEEALRLVYEICPHI+FGHFVAN+SILEAFEGE++ HVVDLGMTLGL HG QWR LI SLA RAG+PP RLRITGVGL  DR +IIG+ELEAYA  L INLEFS VESNLENLRPEDIK  DGE LVVNSILQLHCVVKESRGALNSVLQ ++ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSL+AMLPKYDTRRAK+EQFYF EEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  AKQWLGK+  CEGY I+EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   20 SLSAQAYYSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIAESIGSNSSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWEKKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLEFSAVESNLENLRPEDIKREDGEALVVNSILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWKC 519          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSH-NSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S +AM+CY +PY+P+ E    S +  P+ DE+ + KR+K++ S+ ES+ S+ +SLY GGS        SI RS STNSLN +P+LHFRDHIWTYTQRYL                      +G +DGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGS+FQRVASCFVQGL +RL+LVQPLGAVGF+   MN  D A DKKEEALRLVYEICPHI+FGHFVAN+SILEAFEGES VHVVDLGMTLGLPHG QWR LI+SLA RAG+PPSRLRITGVGL  DR +IIGDELE YA  +GINLEFSVV+S+LENLRPEDIK  + EVLVVNSILQLHCVVKESRGALNSVLQ++ ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD MLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQ APIKM+  AKQWL +  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLAAMACYPHPYLPIFESNVVSRM-LPFSDETRDVKRIKQSSSMVESIRSNGSSLYSGGS--------SICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 516          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHK-RLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDG-TADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            IS SAM+ Y  PY+P+LE  N S     + DE+  HK R+KR +S AES  S      GGS +   +N +ISRS STNSLN+LPRLHFRDHIWTYTQRYL                      +G   DGMRLVQLLIACAEAVACRDKSHASALLSELR++ALVFGSSFQRVASCF QGLA+RL+LVQPLG V  +   MN  D A DKKEEAL LVYEICPHIQFGHFVANSSILEAFEGES+VHVVDLGMTLGLPHG QWR LI+SLA RAG+PP RLRIT VGL   R Q IGDEL  YA  +GINLEFSVVES LENL+P+DIK+ DGEVLVVNSILQLHCVVKESRGALNSVLQ +H LSPKIL LVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLP+YDTRRAKMEQFYFAEEIKNI+SCEGPARVERHE+VDQWRRRMSRAGFQAAP+KM+  AKQWLGK  VC+GYT++EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   24 ISLSAMAYYPYPYLPILEN-NESIFVLDFSDETREHKKRIKRALSFAESTGSDGIYNTGGSGSGSGSNDTISRSCSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEGAEAMANSEEGENHGEGGNTDGMRLVQLLIACAEAVACRDKSHASALLSELRSSALVFGSSFQRVASCFFQGLADRLSLVQPLGTVSLVTPIMNIMDIASDKKEEALSLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGHQWRQLIQSLANRAGKPPCRLRITAVGLCVGRFQTIGDELVEYAKDVGINLEFSVVESTLENLQPDDIKVFDGEVLVVNSILQLHCVVKESRGALNSVLQTIHALSPKILALVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPRYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHEKVDQWRRRMSRAGFQAAPVKMMAQAKQWLGKNKVCDGYTVVEEKGCLVLGWKSKPIVAASCWKC 526          

Query:   19 ISHSAMSCYSNP-YMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNS-LYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXD-GTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S SAM+CY  P Y+P  +  NA +   P+ D++ + KR++R+ S+ ES+ S+NS LY GGS        SI RS STN LN++P+LHFRDHIWTYTQRYL                      + G ADGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGSSFQRVASCFVQGL +RL+LVQPLGAVGF+ + MN  D A DKKEEALRLVYEICPHI+FGHFVAN++ILEAFEGES+VHVVDLGMTLGL HG QWR LIESLA RAG+ PSRLRITGVGL  DR +IIGDEL+ YA  +GINLEFS VESNLENLRPEDIK+ +GEVLVVNSILQLHCVVKESRGALNSVLQ+VHELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERV QWRRRMSRAGFQAAPIKM+  AKQWL K  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLSAMACYPRPPYLPTFDS-NAVSWILPFSDDTRDAKRMRRSSSLVESIRSNNSSLYSGGS--------SICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPT-MNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 517          

Query:   28 SAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXX--DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDK-KEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S + CY  PY+P++ + +A++     + +  + KRLKRTIS+           G GS  S     ++SRS ST+SL+ LPRL FRDHIWTYT+RYL                        DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLA+RLA VQPLGAVG     MN  D A  + KEEA RLVYEICPHIQFGHFVANSSILEAFEGES VHVVDLGMTLGLP G QWR LIESLA RAGQPP RLRIT VGL  ++ Q IGDEL+ YA   GINLEFSVVESNLENL+ +DIK+L+ EVLVVNSILQLHCVVKESRGALNSVLQ++HELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDT+RAK+EQFYFAEEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  A++WL    VCEGYT++EEKGCLVLGWKSKPI+A +CWKC
Sbjct:   29 SIVDCY--PYLPMMSDNSAAS---SMILQPRDQKRLKRTISV-----------GDGSPTS-----TLSRSSSTSSLSNLPRLQFRDHIWTYTRRYLAAEAVEEAAAAMIKSEDGCDGDQQDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLADRLASVQPLGAVGSFAPSMNIMDIAGSREKEEAFRLVYEICPHIQFGHFVANSSILEAFEGESLVHVVDLGMTLGLPRGQQWRRLIESLANRAGQPPRRLRITAVGLCVEKFQSIGDELKDYAKTYGINLEFSVVESNLENLQTKDIKVLENEVLVVNSILQLHCVVKESRGALNSVLQIIHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTKRAKIEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMINQAQKWLKNNKVCEGYTVVEEKGCLVLGWKSKPIIATTCWKC 509          

Query:   52 PYMPLLEEGNASA-LTFPYLDESG----NHKRLKR-TISIA---ESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGT-ADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLG---AVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            P +P+LE    S  +  P+ D       +HK+LKR T++I     + SSH++ +    N++             NS+N++PRLHFRDHI TY QRY                       DG+ ADGMRLVQLLIACAEAVACRDKSHAS LLSEL++NALVFGSSFQRVASCFVQGL  RL L+QP+G   A     S MN  D A ++ EEA +LVYE CPHIQFGHFVANS ILEAFEGES++HVVDLGM+LGLPHG QWRGLI+SLA R+     RLRIT +GL   R+Q+IG+EL  YA  LGI+LEFS+VE NLENL+P+DIK+ + EVLVVNSILQLHCVVKESRGALN+VLQM+H LSPK+LV+ EQDS HNGPFFLGRFME+LHYYSAIFDSLDAMLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHE+VDQWRRRMSRAGFQ +PIKM+V AKQWL K NVC+GYT++EEKGCLVLGWKSKPIVA SCWKC
Sbjct:   30 PNLPILENSATSTWILNPFSDHETETIRDHKKLKRSTVTIPIWFANFSSHSNSFFNNINSN------------NNSVNSIPRLHFRDHIRTYKQRYFASEAVEEAAEDNFNYNNCEAEEDGSCADGMRLVQLLIACAEAVACRDKSHASVLLSELKSNALVFGSSFQRVASCFVQGLTERLTLIQPIGNNSAGSDTKSMMNIMDAASEEMEEAFKLVYENCPHIQFGHFVANSIILEAFEGESFLHVVDLGMSLGLPHGHQWRGLIQSLADRSSHRVRRLRITAIGLCIARIQVIGEELSIYAKNLGIHLEFSIVEKNLENLKPKDIKVNEKEVLVVNSILQLHCVVKESRGALNAVLQMIHGLSPKVLVMAEQDSGHNGPFFLGRFMESLHYYSAIFDSLDAMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHEKVDQWRRRMSRAGFQGSPIKMVVQAKQWLVKNNVCDGYTVVEEKGCLVLGWKSKPIVAVSCWKC 521          

Query:    7 AFDLISHSAMSCYSNPYMPLLEEGNASALT-FPYLDES--GNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTAD-GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSP-MNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRA-GQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            AFD+ + +  +    P+ P + E ++S L  FP+ D +   ++KR+KRT+           +Y   S +S     S SR       N++P+LHFRDHI TYTQRYL                      + + D  MRLVQLLIACAEAVACRDKSHAS LLSEL+ANALVFGSSFQRVASCFVQGL  RL L+QP+G+ G + +P MN  D A D+ EEA RLVYE+CPHIQFGH++ANS++LEAFEGES+VHVVDLGM+LGL HG QWR LI+SLA RA G+   RLRITGVGL   R+Q IG+EL  YA+ LGINLEFSVV  NLENL+PEDI++ + EVLVVNSILQLHCVVKESRGALNSVLQM+H L PK+LV+VEQDSSHNGPFFLGRFME+LHYYS+IFDSLD MLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHERVDQWRRRMSRAGFQAAPIKM+  +KQWL K  VCEGYT++EEKGCLV GWKS+PIVA SCWKC
Sbjct:   20 AFDIWATNLWAYGYYPHQPAISENSSSKLVDFPFCDGTIIRDNKRVKRTVCFP--------IYNSVSCHSFFNTNSSSR-------NSIPKLHFRDHIRTYTQRYLAAEPVE----------------EASEDTNMRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLTERLNLIQPIGSAGPMMAPAMNIMDAASDEMEEAYRLVYELCPHIQFGHYLANSTVLEAFEGESFVHVVDLGMSLGLRHGHQWRALIQSLANRASGERVRRLRITGVGLCV-RLQTIGEELSVYANNLGINLEFSVVNKNLENLKPEDIEVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQSKQWLLKNKVCEGYTVVEEKGCLVFGWKSRPIVAVSCWKC 499          

Query:   43 YSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            YS P++P+ +    +      LDE+ +HKR+K      ES+ +    Y   SN      GSI+     N LN+LPRLHFRD+I  YT+RYL                      +   DGM+LVQ LIACAEAVACRDK+HASALLSELRANALVFG+SFQRVASCFVQGL++RL L+QPLGAVG +G       F  +K +EALRLVYEICP IQFG+FVAN++ILEAFEGES +HVVDLGMTLGLPHG+QWR L+  LA R  + P  LRITGVG   +R+Q +GDEL+ YA  LG+N EF  VES+LE L+  D KLLDGEV+++NSILQLHC VKESRGALN+VLQ++HELSPK+L+LVEQDS HNGPFFLGR MEALHYYSAIFDSLD MLPKYDT+R K+EQF++ EEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQ A IKM + AKQWLGK  VCEGYT+ E+KGCL+LGWKSKPI+AASCWKC
Sbjct:   29 YSIPHIPVSKNSRPTCFD---LDETRSHKRVKP--GGVESIGNGIGCYAVSSNG-----GSIN----ANCLNSLPRLHFRDYIRAYTERYLAIEAMEEAAAGLMISKKNEIKEEDI-DGMKLVQQLIACAEAVACRDKTHASALLSELRANALVFGTSFQRVASCFVQGLSDRLTLLQPLGAVGVLGPAGKTISFTAEK-DEALRLVYEICPQIQFGYFVANATILEAFEGESSIHVVDLGMTLGLPHGEQWRNLLHCLANRPDKKPRCLRITGVGNSAERLQALGDELDCYARSLGLNFEFLWVESSLEKLKSTDFKLLDGEVVIINSILQLHCAVKESRGALNTVLQILHELSPKLLILVEQDSGHNGPFFLGRVMEALHYYSAIFDSLDTMLPKYDTKRVKIEQFFYGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQPAQIKMAMQAKQWLGKAKVCEGYTVTEDKGCLILGWKSKPIIAASCWKC 506          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVG-FIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAG-QPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            DG ADG+RLVQLLIACAEAVACRDKSHAS LLSEL+ANALVFGSSFQRVASCFVQGL  RL L+QP+G  G  + S MN  D A D+ EEA RLVYE+CPHIQFGH++ANS+ILEAFEGES+VHVVDLGM+LGL HG QWRGLI++LA R G +   RLRITGVGL  +R+Q IG+EL  YA+ LG+NLEFSVVE NLENL+PEDIK+ + EVLVVNSILQLHCVVKESRGALNSVLQM+H L PK+LV+VEQDSSHNGPFFLGRFME+LHYYS+IFDSLD MLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHERVDQWRRRMSRAGFQAAPIKM+  AKQWL K  VCEGYT++EEKGCLVLGWKS+PIVA SCWKC
Sbjct:   95 DGCADGVRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLIERLNLIQPIGPAGPMMPSMMNIMDVASDEMEEAFRLVYELCPHIQFGHYLANSTILEAFEGESFVHVVDLGMSLGLRHGHQWRGLIQNLAGRVGGERVRRLRITGVGLC-ERLQTIGEELSVYANNLGVNLEFSVVEKNLENLKPEDIKVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQAKQWLLKNKVCEGYTVVEEKGCLVLGWKSRPIVAVSCWKC 476          

Query:  382 DGTA-DGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQP--LG--AVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            DG+A DGMRLVQLL+ACAEAVACRD++ A+ALL EL+  A V G++FQRVASCFVQGLA+RLAL  P  LG  ++ F     +  D A   + EAL + Y++CP+++F HFVAN+SILEAFEGE+ VHVVDLGMT+GL  G QWR L++ LATRA   P+R+RITGVG   D M+ +G ELEAYAD LGI LEF  V+  LE+L+ +D+ +   E + +NS+L+LHCVVKESRGALNSVLQ + +LSPK  VLVEQD+ HNGPFFLGRFMEALHYY+A+FD+LDA LP+YD RRA++EQF++  EI+N++ CEG ARVERHER DQWRRRMSRAGFQ+ P KM   A++WL +     GYT+ EEKGCLVLGWK KP++AASCWKC
Sbjct:  134 DGSAADGMRLVQLLVACAEAVACRDRAQAAALLRELQVGAPVHGTAFQRVASCFVQGLADRLALAHPPSLGPASMAFCVPRSSCLDGA---RGEALAVAYDLCPYLRFAHFVANTSILEAFEGETNVHVVDLGMTMGLNRGHQWRALLDGLATRASGKPARVRITGVGARVDTMRAVGRELEAYADELGITLEFMAVDRTLESLQVDDLGIDVDEAVAINSVLELHCVVKESRGALNSVLQTIRKLSPKAFVLVEQDAGHNGPFFLGRFMEALHYYAALFDALDAALPRYDARRARVEQFHYGAEIRNVVGCEGAARVERHERADQWRRRMSRAGFQSMPFKMAAKAREWLEENAGGSGYTVAEEKGCLVLGWKGKPVIAASCWKC 516          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAM-LPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEAV   +   A AL+ ++   A+    + ++VA+ F +GLA R+  + P              D  LD    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  G+    QW  L+++LA R G PPS  R+TG+G       D +  +G +L   A+ + +  E+   V ++L +L    ++L DGE + VNS+ +LH ++    G +  VL  V ++ P I+ +VEQ+++HNGP FL RF E+LHYYS +FDSL+   +   +T+   M + Y  ++I N+++CEGP RVERHE + QWR R+  AGF   P+ +  N    A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:  206 DSQETGIRLVHTLMACAEAVQQENLKLAEALVKQIGFLAVSQAGAMRKVATYFAEGLARRIYRLYP--------------DKPLDSSFSDILQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMKQGM----QWPALMQALALRPGGPPS-FRLTGIGPPSTDNTDHLHEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRDGESVAVNSVFELHSLLARP-GGIERVLSAVKDMKPDIVTIVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGCGVSPVNTQDKLMSEVYLGQQICNVVACEGPERVERHETLAQWRARLGSAGFD--PVNLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 575          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF--------SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEA+   D S A AL+ ++   A+    + ++VA+ F + LA R+  + P         P    D +L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  GL    QW  L+++LA R G PP   R+TG+G       D +  +G +L   A+ + +  E+        + +++++  LRP +I     E + VNS+ +LH ++  + G +  VL +V ++ P I  +VEQ+SSHNGP FL RF E+LHYYS +FDSL+ +    D     M + Y  ++I N+++CEGP RVERHE + QW  R   +GF  A +       A   L   N  EGY + E  GCL+LGW ++P++  S WK
Sbjct:  206 DSQENGVRLVHALMACAEAIQNNDLSIAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYRLSP---------PQTQIDHSLS---DTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGPPV-FRLTGIGPPAADNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSEI-----EAVAVNSVFELHKLLGRT-GGIEKVLGVVKQIKPVIFTVVEQESSHNGPVFLDRFTESLHYYSTLFDSLEGVPSSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWANRFGSSGFAPAHLGSNAFKQASMLLALFNGGEGYRVEENNGCLMLGWHTRPLITTSAWK 574          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDG-EVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEAV   +   A AL+  +   A     + ++VA+ F +GLA R+  + P              D AL    + L++  YE CP+++F HF AN +ILE F     VHV+DLG+     HG QW  LI++LA R   PP   R+TG+G     +Q +G +L   A  +G+N EF S+  +NL +L+PE + +  G E + VNS+ +LH ++    G+++  L  +  + P I+ +VEQ+++HNG  FL RF E+LHYYS++FDSL+   P  D     M + +   +I N+++CEG  RVERHE ++QWR R    GF+   I       A   L      +GY + E +GCL+LGW+++P++A S W+
Sbjct:  144 DSQETGVRLVHALLACAEAVQQNNLKLADALVKHVGLLASSQAGAMRKVATYFAEGLARRIYRIYP------------RDDVALSSFSDTLQIHFYESCPYLKFAHFTANQAILEVFATAEKVHVIDLGLN----HGLQWPALIQALALRPNGPPD-FRLTGIGYSLTDIQEVGWKLGQLASTIGVNFEFKSIALNNLSDLKPEMLDIRPGLESVAVNSVFELHRLLAHP-GSIDKFLSTIKSIRPDIMTVVEQEANHNGTVFLDRFTESLHYYSSLFDSLEGP-PSQD---RVMSELFLGRQILNLVACEGEDRVERHETLNQWRNRFGLGGFKPVSIGSNAYKQASMLLALYAGADGYNVEENEGCLLLGWQTRPLIATSAWR 506          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF--------SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEAV   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P        SP+   D +L    + L++  YE CP+++F HF AN +ILEAF+G+  VHV+D  M+ GL    QW  L+++LA R G PP   R+TG+G       D +  +G +L   A+ + +  E+        + +++++  LRP +I     E + VNS+ +LH ++    GA++ VL +V+++ P+I  +VEQ+S+HN P FL RF E+LHYYS +FDSL+ +    D     M + Y  ++I N+++C+GP RVERHE + QWR R   AGF AA I       A   L   N  EGY + E  GCL+LGW ++P++A S WK
Sbjct:  161 DSQENGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQ------SPI---DHSLS---DTLQMHFYETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGL----QWPALMQALALRPGGPPV-FRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEI-----ESVAVNSVFELHKLLGRP-GAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQD---KVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWK 529          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLL--DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEA+   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P         P N  D  L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  GL    QW  L+++LA R G PP+  R+TG+G       D +  +G +L   A+ + +  E+   V ++L +L    ++L   D E + VNS+ +LH ++    G +  VL +V ++ P I  +VEQ+S+HNGP FL RF E+LHYYS +FDSL+ +    D     M + Y  ++I N+++CEGP RVERHE + QW  R   +G   A +       A   L   N  +GY + E  GCL+LGW ++P++  S WK
Sbjct:  213 DSQENGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSP---------PQNQIDHCLS---DTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGPPT-FRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRP-GGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWK 581          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLL--DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEAV   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P         P    D +L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  GL    QW  L+++LA R G PPS  R+TG+G       D +  +G +L   A+ + +  E+   V ++L +L    ++L   + E + VNS+ +LH ++  + G +  V  +V ++ P I  +VEQ+S+HNGP FL RF E+LHYYS +FDSL+      D     M + Y  ++I N+++CEGP RVERHE + QW  R   +GF  A +       A   L   N  EGY + E  GCL+L W ++P++  S WK
Sbjct:  200 DSQDNGVRLVHALMACAEAVQSSNLTLAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYRLSP---------PQTQIDHSLS---DTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGPPS-FRLTGIGPPAADNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSETEAVAVNSVFELHKLLGRT-GGIEKVFGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGAPSSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWSNRFGSSGFAPAHLGSNAFKQASTLLALFNGGEGYRVEENNGCLMLSWHTRPLITTSAWK 568          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEV--LVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNA-KQ---WLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G++LV  L+ CAEAV   + + A AL+  +   A+    + ++VA+ F + LA R+  + P        +P++     LD  +      YE CP+++F HF AN +ILEAFEG+  VHV+D  M  G+    QW  LI++LA R   PP+  R+TG+G       D +Q +G +L  +A+ L +  E+   V ++L +L    ++L   EV  +VVNS+ +LH ++    GA+  VL +V ++ P+I+ +VEQ+++HNGP F+ RF E+LHYYS +FDSL+      D     M + Y  ++I N+++CEG  RVERHE + QWR R+S AGF   PI +  NA KQ    L      EGY + E +G L+LGW ++P++A S WK
Sbjct:  203 DSQENGIQLVHALMVCAEAVQQNNLNLAEALVKRIDYLAVSQAGAMRKVATFFAEALARRIYRLCP-------ENPLDRS--VLDMLQMHF---YESCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGI----QWPALIQALALRPSGPPT-FRLTGIGPPAPDNSDYLQDVGWKLVKFAETLHVEFEYRGFVANSLADLDASMLELRPSEVESVVVNSVFELHQLLARP-GAIEKVLSVVKQMKPEIVTVVEQEANHNGPVFVERFTESLHYYSTLFDSLECSPNSQD---KMMSEMYLGKQICNVVACEGADRVERHETLTQWRTRLSSAGFD--PIHLGSNAFKQASILLALFGSGEGYRVEENEGSLMLGWHTRPLIATSAWK 570          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDR--MQIIGDELEAYADRLGINLEFS-VVESNLENLRPEDIKL-LDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD--AMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G+RLVQ L+ACAEAV   + S A AL+  +   A     +  +VA+ F + LA R+  + P  A             A+D   EE L++  Y+ CP+++F HF AN +ILEA      VHV+DLG+  G+    QW  L+++LA R G PPS  R+TGVG   +R  +Q +G +L   A  +G+  +F+ +    L +L P+  +   + E LVVNS+ +LH V+ +  G++  +L  V  + P ++ +VEQ+++HNG  FL RF EALHYYS++FDSL+   ++P  D     M + Y   +I N+++ EG  R+ERHE + QWR+RM  AGF    +       A   L      +GY + E  G L+L W++KP++AAS WK
Sbjct:  154 GVRLVQALVACAEAVQLENLSLADALVKRVGLLAASQAGAMGKVATYFAEALARRIYRIHPSAA-------------AIDPSFEEILQMNFYDSCPYLKFAHFTANQAILEAVTTSRVVHVIDLGLNQGM----QWPALMQALALRPGGPPS-FRLTGVGNPSNREGIQELGWKLAQLAQAIGVEFKFNGLTTERLSDLEPDMFETRTESETLVVNSVFELHPVLSQP-GSIEKLLATVKAVKPGLVTVVEQEANHNGDVFLDRFNEALHYYSSLFDSLEDGVVIPSQD---RVMSEVYLGRQILNLVATEGSDRIERHETLAQWRKRMGSAGFDPVNLGSDAFKQASLLLALSGGGDGYRVEENDGSLMLAWQTKPLIAASAWK 516          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPE--DIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVA 1506
            D    G+RLV  L+ACAEAV   +   A AL+  +   A     + ++VA+ F + LA R+  + P         P +      DK +      YE CP+++F HF AN +ILEAF   S VHV+D G+  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A+R+GI  EF   V ++L +L PE  DI+  + EV+ VN++ +LH ++    G +  V+  +  + PKI+ +VEQ+++HNGP FL RF EALHYYS +FDSL+       ++   M + Y   +I N+++CEG  RVERHE + QWR RM  AG   +P+ +  N    A   L      +GY + E  GCL+LGW ++P++A
Sbjct:  163 DSQEAGVRLVHTLMACAEAVQQDNLKLADALVKHIGLLASSQTGAMRKVATYFAEALARRIYRIFP---------PDSLDPSYNDKLQIPF---YETCPYLKFAHFTANQAILEAFSMASRVHVIDFGLKQGM----QWPALMQALALRPGGPPA-FRLTGIGPPQPDNTDALQQVGWKLAQLAERIGIEFEFRGFVANSLADLEPEMLDIRPPEIEVVAVNAVFELHPLLARP-GGIEKVVSSIKAMKPKIVTVVEQEANHNGPVFLDRFTEALHYYSTLFDSLEGSGVAPASQDLAMSELYLGRQICNVVACEGMDRVERHEPLTQWRTRMETAG--VSPVHLGSNAYKQASMLLALFASGDGYRVEENNGCLMLGWHTRPLIA 528          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEFS-VVESNLENLRPEDIKLL-DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD--AMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEA+   + + A AL+  +   A     +  +VA+ F Q LA R+   +   A   + + +N         EE L +  YE CP+++F HF AN +ILEA      VHV+DLG+  G+    QW  L+++LA R G PPS  R+TG+G       D +Q +G +L  +A  +G+  EF  +   +L +L PE  +   + E LVVNS+ +LH ++  S G++  +L  V  + P I+ +VEQ+++HNG  FL RF EALHYYS++FDSL+    LP  D     M + Y   +I N+++ EG  RVERHE   QWR RM  AGF    +       A   L      +GY + E  GCL++GW+++P++  S WK
Sbjct:  172 DSQETGVRLVHALVACAEAIHQENLNLADALVKRVGTLAGSQAGAMGKVATYFAQALARRI--YRDYTAETDVCAAVNPSF------EEVLEMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGM----QWPALMQALALRPGGPPS-FRLTGIGPPQTENSDSLQQLGWKLAQFAQNMGVEFEFKGLAAESLSDLEPEMFETRPESETLVVNSVFELHRLLARS-GSIEKLLNTVKAIKPSIVTVVEQEANHNGIVFLDRFNEALHYYSSLFDSLEDSYSLPSQD---RVMSEVYLGRQILNVVAAEGSDRVERHETAAQWRIRMKSAGFDPIHLGSSAFKQASMLLSLYATGDGYRVEENDGCLMIGWQTRPLITTSAWK 545          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDG-EVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEAV   +   A AL+  +   A     + ++VA+ F +GLA R+  + P              D AL    + L++  YE CP+++F HF AN +ILE F     VHV+DLG+     HG QW  LI++LA R   PP   R+TG+G     +Q +G +L   A  +G+N EF S+  +NL +L+PE + +  G E + VNS+ +LH ++    G+++  L  +  + P I+ +VEQ+++HNG  FL RF E+LHYYS++FDSL+   P  D     M + +   +I N+++CEG  RVERHE ++QWR R    GF+   I       A   L      +GY + E +GCL+LGW+++P++A S W+
Sbjct:  144 DSQETGVRLVHALLACAEAVQQNNLKLADALVKHVGLLASSQAGAMRKVATYFAEGLARRIYRIYP------------RDDVALSSFSDTLQIHFYESCPYLKFAHFTANQAILEVFATAEKVHVIDLGLN----HGLQWPALIQALALRPNGPPD-FRLTGIGYSLTDIQEVGWKLGQLASTIGVNFEFKSIALNNLSDLKPEMLDIRPGLESVAVNSVFELHRLLAHP-GSIDKFLSTIKSIRPDIMTVVEQEANHNGTVFLDRFTESLHYYSSLFDSLEGP-PSQD---RVMSELFLGRQILNLVACEGEDRVERHETLNQWRNRFGLGGFKPVSIGSNAYKQASMLLALYAGADGYNVEENEGCLLLGWQTRPLIATSAWR 506          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF--------SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEAV   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P        SP+   D +L    + L++  YE CP+++F HF AN +ILEAF+G+  VHV+D  M+ GL    QW  L+++LA R G PP   R+TG+G       D +  +G +L   A+ + +  E+        + +++++  LRP +I     E + VNS+ +LH ++    GA++ VL +V+++ P+I  +VEQ+S+HN P FL RF E+LHYYS +FDSL+ +    D     M + Y  ++I N+++C+GP RVERHE + QWR R   AGF AA I       A   L   N  EGY + E  GCL+LGW ++P++A S WK
Sbjct:  161 DSQENGVRLVHALLACAEAVQKENLTVAEALVKQIGFLAVSQIGAMRKVATYFAEALARRIYRLSPSQ------SPI---DHSLS---DTLQMHFYETCPYLKFAHFTANQAILEAFQGKKRVHVIDFSMSQGL----QWPALMQALALRPGGPPV-FRLTGIGPPAPDNFDYLHEVGCKLAHLAEAIHVEFEYRGFVANTLADLDASMLELRPSEI-----ESVAVNSVFELHKLLGRP-GAIDKVLGVVNQIKPEIFTVVEQESNHNSPIFLDRFTESLHYYSTLFDSLEGVPSGQD---KVMSEVYLGKQICNVVACDGPDRVERHETLSQWRNRFGSAGFAAAHIGSNAFKQASMLLALFNGGEGYRVEESDGCLMLGWHTRPLIATSAWK 529          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLL--DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEA+   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P         P N  D  L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  GL    QW  L+++LA R G PP+  R+TG+G       D +  +G +L   A+ + +  E+   V ++L +L    ++L   D E + VNS+ +LH ++    G +  VL +V ++ P I  +VEQ+S+HNGP FL RF E+LHYYS +FDSL+ +    D     M + Y  ++I N+++CEGP RVERHE + QW  R   +G   A +       A   L   N  +GY + E  GCL+LGW ++P++  S WK
Sbjct:  213 DSQENGVRLVHALMACAEAIQQNNLTLAEALVKQIGCLAVSQAGAMRKVATYFAEALARRIYRLSP---------PQNQIDHCLS---DTLQMHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGL----QWPALMQALALREGGPPT-FRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLADLDASMLELRPSDTEAVAVNSVFELHKLLGRP-GGIEKVLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGVPNSQD---KVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGLAPAHLGSNAFKQASMLLSVFNSGQGYRVEESNGCLMLGWHTRPLITTSAWK 581          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDR--MQIIGDELEAYADRLGINLEFS-VVESNLENLRPEDIKL-LDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD--AMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G+RLVQ L+ACAEAV   + S A AL+  +   A     +  +VA+ F + LA R+  + P  A             A+D   EE L++  Y+ CP+++F HF AN +ILEA      VHV+DLG+  G+    QW  L+++LA R G PPS  R+TGVG   +R  +Q +G +L   A  +G+  +F+ +    L +L P+  +   + E LVVNS+ +LH V+ +  G++  +L  V  + P ++ +VEQ+++HNG  FL RF EALHYYS++FDSL+   ++P  D     M + Y   +I N+++ EG  R+ERHE + QWR+RM  AGF    +       A   L      +GY + E  G L+L W++KP++AAS WK
Sbjct:  154 GVRLVQALVACAEAVQLENLSLADALVKRVGLLAASQAGAMGKVATYFAEALARRIYRIHPSAA-------------AIDPSFEEILQMNFYDSCPYLKFAHFTANQAILEAVTTSRVVHVIDLGLNQGM----QWPALMQALALRPGGPPS-FRLTGVGNPSNREGIQELGWKLAQLAQAIGVEFKFNGLTTERLSDLEPDMFETRTESETLVVNSVFELHPVLSQP-GSIEKLLATVKAVKPGLVTVVEQEANHNGDVFLDRFNEALHYYSSLFDSLEDGVVIPSQD---RVMSEVYLGRQILNLVATEGSDRIERHETLAQWRKRMGSAGFDPVNLGSDAFKQASLLLALSGGGDGYRVEENDGSLMLAWQTKPLIAASAWK 516          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEFS-VVESNLENLRPEDIKLL-DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD--AMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEA+   + + A AL+  +   A     +  +VA+ F Q LA R+   +   A   + + +N         EE L +  YE CP+++F HF AN +ILEA      VHV+DLG+  G+    QW  L+++LA R G PPS  R+TG+G       D +Q +G +L  +A  +G+  EF  +   +L +L PE  +   + E LVVNS+ +LH ++  S G++  +L  V  + P I+ +VEQ+++HNG  FL RF EALHYYS++FDSL+    LP  D     M + Y   +I N+++ EG  RVERHE   QWR RM  AGF    +       A   L      +GY + E  GCL++GW+++P++  S WK
Sbjct:  172 DSQETGVRLVHALVACAEAIHQENLNLADALVKRVGTLAGSQAGAMGKVATYFAQALARRI--YRDYTAETDVCAAVNPSF------EEVLEMHFYESCPYLKFAHFTANQAILEAVTTARRVHVIDLGLNQGM----QWPALMQALALRPGGPPS-FRLTGIGPPQTENSDSLQQLGWKLAQFAQNMGVEFEFKGLAAESLSDLEPEMFETRPESETLVVNSVFELHRLLARS-GSIEKLLNTVKAIKPSIVTVVEQEANHNGIVFLDRFNEALHYYSSLFDSLEDSYSLPSQD---RVMSEVYLGRQILNVVAAEGSDRVERHETAAQWRIRMKSAGFDPIHLGSSAFKQASMLLSLYATGDGYRVEENDGCLMIGWQTRPLITTSAWK 545          

Query:  412 QLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGV--------GLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLV-NAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            Q+LI+CA A++      A ++++ELR    + G   QR+A+  V+GLA R+A      +  FI   +  K+   D++  A+++++E+CP  +FG   AN +ILEA +GE  VH++D  +      G+Q+  LI S+A   G+ P RLR+TG+         + G  ++IIG  LE  A+  G++ +F  + S    + P  +    GE L+VN   QLH +  ES   +N    +L MV  L+PK++ +VEQD + N   F  RF+EA  YYSA+F+SLD  LP+    R  +E+   A +I NI++CEG  R+ER+E   +WR RM  AGF   P+   V N  Q L K   C  Y + EE G L   W+ K ++ AS W+
Sbjct:  224 QILISCARALSEGKLEEALSMVNELRQIVSIQGDPSQRIAAYMVEGLAARMA-----ASGKFIYRALKCKEPPSDERLAAMQVLFEVCPCFKFGFLAANGAILEAIKGEEEVHIIDFDIN----QGNQYMTLIRSIAELPGKRP-RLRLTGIDDPESVQRSIGG--LRIIGLRLEQLAEDNGVSFKFKAMPSKTSIVSPSTLGCKPGETLIVNFAFQLHHMPDESVTTVNQRDELLHMVKSLNPKLVTVVEQDVNTNTSPFFPRFIEAYEYYSAVFESLDMTLPRESQERMNVERQCLARDIVNIVACEGEERIERYEAAGKWRARMMMAGFNPKPMSAKVTNNIQNLIKQQYCNKYKLKEEMGELHFCWEEKSLIVASAWR 593          

Query:  418 LIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMN-AKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVG------LYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            L++CA+A++  D   A +++ +LR    V G   QR+ +  ++GL  +LA      +   I   +N   + A  +    + ++YE+CP+ +FG+  AN +I EA + E+ VH++D      +  G QW  LI++ A R G PP R+RITG+         G  + I+G+ L   A +  +  EF+ V  ++  ++P+++ +  GE L VN    LH +  ES    N    +L+MV  LSPK++ LVEQ+S+ N   F  RFME ++YY+A+F+S+D  LP+   +R  +EQ   A ++ NII+CEG  RVERHE + +WR R   AGF   P+  LVN+       N  + Y + E  G L LGW  + +VA+  WK
Sbjct:  123 LVSCAKAMSENDLMMAHSMMEKLRQMVSVSGEPIQRLGAYLLEGLVAQLA-----SSGSSIYKALNRCPEPASTELLSYMHILYEVCPYFKFGYMSANGAIAEAMKEENRVHIIDFQ----IGQGSQWVTLIQAFAARPGGPP-RIRITGIDDMTSAYARGGGLSIVGNRLAKLAKQFNVPFEFNSVSVSVSEVKPKNLGVRPGEALAVNFAFVLHHMPDESVSTENHRDRLLRMVKSLSPKVVTLVEQESNTNTAAFFPRFMETMNYYAAMFESIDVTLPRDHKQRINVEQHCLARDVVNIIACEGADRVERHELLGKWRSRFGMAGFTPYPLSPLVNSTIKSLLRNYSDKYRLEERDGALYLGWMHRDLVASCAWK 490          

Query:  418 LIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMN-AKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVG------LYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            L++CA+A++  D   A +++ +LR    V G   QR+ +  ++GL  +LA      +   I   +N   + A  +    + ++YE+CP+ +FG+  AN +I EA + E+ VH++D      +  G QW  LI++ A R G PP R+RITG+         G  + I+G+ L   A +  +  EF+ V  ++  ++P+++ +  GE L VN    LH +  ES    N    +L+MV  LSPK++ LVEQ+S+ N   F  RFME ++YY+A+F+S+D  LP+   +R  +EQ   A ++ NII+CEG  RVERHE + +WR R   AGF   P+  LVN+       N  + Y + E  G L LGW  + +VA+  WK
Sbjct:  123 LVSCAKAMSENDLMMAHSMMEKLRQMVSVSGEPIQRLGAYLLEGLVAQLA-----SSGSSIYKALNRCPEPASTELLSYMHILYEVCPYFKFGYMSANGAIAEAMKEENRVHIIDFQ----IGQGSQWVTLIQAFAARPGGPP-RIRITGIDDMTSAYARGGGLSIVGNRLAKLAKQFNVPFEFNSVSVSVSEVKPKNLGVRPGEALAVNFAFVLHHMPDESVSTENHRDRLLRMVKSLSPKVVTLVEQESNTNTAAFFPRFMETMNYYAAMFESIDVTLPRDHKQRINVEQHCLARDVVNIIACEGADRVERHELLGKWRSRFGMAGFTPYPLSPLVNSTIKSLLRNYSDKYRLEERDGALYLGWMHRDLVASCAWK 490          

Query:  394 DGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCW 1518
            +G+ L+ LL+ CAEAV+  +   A+ LL E+   +  +G+S QRVA+ F + ++ RL L   LG    + S    +  +L K   A ++   I P ++F HF AN +I EAFE E  VH++DL +  GL    QW GL   LA+R G PP  +R+TG+G   + +Q  G  L  +AD+LG+  EF  +   + NL  E + +   E + V+    L   + +  G+    L ++  L+PK++ +VEQD SH G F LGRF+EA+HYYSA+FDSL A   +    R  +EQ   ++EI+N+++  GP+R     + + WR +M + GF+   +       A   LG     +GYT++++ G L LGWK   ++ AS W
Sbjct:  286 EGLHLLTLLLQCAEAVSADNLEEANKLLLEISQLSTPYGTSAQRVAAYFSEAMSARL-LNSCLGIYAALPSRWMPQTHSL-KMVSAFQVFNGISPLVKFSHFTANQAIQEAFEKEDSVHIIDLDIMQGL----QWPGLFHILASRPGGPP-HVRLTGLGTSMEALQATGKRLSDFADKLGLPFEFCPLAEKVGNLDTERLNVRKREAVAVH---WLQHSLYDVTGSDAHTLWLLQRLAPKVVTVVEQDLSHAGSF-LGRFVEAIHYYSALFDSLGASYGEESEERHVVEQQLLSKEIRNVLAVGGPSR-SGEVKFESWREKMQQCGFKGISLAGNAATQATLLLGMF-PSDGYTLVDDNGTLKLGWKDLSLLTASAW 649          

Query:  415 LLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            +L+ACA+AV+  +   A   + ELR    + G   QR+ +  ++GL  RLA      +   I   + +++    +    + +++E+CP+ +FG+  AN +I EA + E  +H++D      +  G QW  LI++ A R G  P+ +RITGVG  G  +  +   LE  A +  +   F+ V      +  E++ + DGE L VN    LH +  ES    N    +L+MV  LSPK++ LVEQ+ + N   FL RF+E L YY+A+F+S+D MLP+    R  +EQ   A ++ NII+CEG  R+ERHE + +W+ R S AGF+  P+  +++A       +   GY I E  G L LGW  + +V++  WK
Sbjct:   53 VLVACAKAVSENNLLMARWCMGELRGMVSISGEPIQRLGAYMLEGLVARLA-----ASGSSIYKSLQSREPESYEFLSYVYVLHEVCPYFKFGYMSANGAIAEAMKDEERIHIIDFQ----IGQGSQWIALIQAFAARPGGAPN-IRITGVG-DGSVLVTVKKRLEKLAKKFDVPFRFNAVSRPSCEVEVENLDVRDGEALGVNFAYMLHHLPDESVSMENHRDRLLRMVKSLSPKVVTLVEQECNTNTSPFLPRFLETLSYYTAMFESIDVMLPRNHKERINIEQHCMARDVVNIIACEGAERIERHELLGKWKSRFSMAGFEPYPLSSIISATIRALLRDYSNGYAIEERDGALYLGWMDRILVSSCAWK 413          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSH-NSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S +AM+CY +PY+P+ E    S +  P+ DE+ + KR+K++ S+ ES+ S+ +SLY GGS        SI RS STNSLN +P+LHFRDHIWTYTQRYL                      +G +DGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGS+FQRVASCFVQGL +RL+LVQPLGAVGF+   MN  D A DKKEEALRLVYEICPHI+FGHFVAN+SILEAFEGES VHVVDLGMTLGLPHG QWR LI+SLA RAG+PPSRLRITGVGL  DR +IIGDELE YA  +GINLEFSVV+S+LENLRPEDIK  + EVLVVNSILQLHCVVKESRGALNSVLQ++ ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD MLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQ APIKM+  AKQWL +  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLAAMACYPHPYLPIFESNVVSRM-LPFSDETRDVKRIKQSSSMVESIRSNGSSLYSGGS--------SICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 516          

Query:   19 ISHSAMSCYSNP-YMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNS-LYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXD-GTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S SAM+CY  P Y+P  +  NA +   P+ D++ + KR++R+ S+ ES+ S+NS LY GGS        SI RS STN LN++P+LHFRDHIWTYTQRYL                      + G ADGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGSSFQRVASCFVQGL +RL+LVQPLGAVGF+ + MN  D A DKKEEALRLVYEICPHI+FGHFVAN++ILEAFEGES+VHVVDLGMTLGL HG QWR LIESLA RAG+ PSRLRITGVGL  DR +IIGDEL+ YA  +GINLEFS VESNLENLRPEDIK+ +GEVLVVNSILQLHCVVKESRGALNSVLQ+VHELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERV QWRRRMSRAGFQAAPIKM+  AKQWL K  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLSAMACYPRPPYLPTFDS-NAVSWILPFSDDTRDAKRMRRSSSLVESIRSNNSSLYSGGS--------SICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPT-MNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 517          

Query:  385 GTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGF--IGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGV--GLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENL--RPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G   G+ LV LL+ACAEA++CRD   A  +LS++  +   +G S QRV+ CF  GL  RL+ +  + A G   IG  M+       +K EA +L+++  P+I FG   AN +I +A + +  +H++DLGM     H  QW  L+  LA+R   PP +LRITG+  G     ++    EL   A  LGI LEF++V   +  L    E++ L +GE L VNSI+ LH  VKESRG+L ++LQ + +L+P +L +VEQD++HNGPFFLGRF+E+LHYYSAIFDSL+A LP+   +R KME+  F+ EI NII+ EG  R+ERHER DQWRR++SRAGFQ   +K +  A+  L    + +GYT+  EKGCL+LGWK +PI+ AS W+
Sbjct:  150 GVDQGLHLVHLLLACAEALSCRDTRLAETMLSQIWPSVSPWGDSLQRVSFCFAMGLKCRLSHLNNVNAHGTFTIGGAMDRSLIVRAEKMEAFQLLHQATPYIAFGFMAANEAICQAAQEKDSLHIIDLGME----HALQWPSLMRILASRPEGPP-KLRITGLIDGHNLLELEASMKELAEEASSLGIRLEFNLVSEPVSPLLLTTENLNLREGEALFVNSIMHLHKFVKESRGSLKAILQAIKKLNPTLLTVVEQDANHNGPFFLGRFIESLHYYSAIFDSLEASLPRNSPQRIKMEKVQFSTEICNIIAYEGSNRIERHERADQWRRQLSRAGFQVMGLKCMSQARMMLSVYGI-DGYTLATEKGCLLLGWKGRPIMLASAWQ 528          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALV---QPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            G++L+ LL+ACAEAV+  D   A   L  L       G S QRVASCF + L+ RLA     +P  +     SP       + K     +++Y+ CP+++F HF AN +I EAFE E  VHV+DL +  G     QW   +++LA R G  P  LRITGVG   + ++  G  L   A  L +  E+  V   L +L+P       GE L VNS+ +LH V       L ++L M+ + +P I+ +VEQ++SHNGP+FLGRF+EALHYYSAIFDSLD+  P   ++RAK+EQ+ FA EI+NI++CEG  R ERHER+++WR+ M   GF+  P+    +  +K  LG +  C+GY + E+KGCL+LGW+ + I+AAS W+C
Sbjct:  311 GLQLLNLLLACAEAVSNEDYMLARRYLHHLNRVVSPLGDSMQRVASCFTEALSARLAATLTTKPSTSSSKAFSPFPPNSMEILK---IYQILYQACPYVKFAHFTANQAIFEAFETEERVHVIDLDILQGY----QWPAFMQALAARPGGAPF-LRITGVGSSMENVRETGRCLTELAHSLHVPFEYHPVAEELVDLKPHMFNRRVGEALAVNSVNRLHRV---PGNCLGNLLAMIRDQAPNIVTVVEQEASHNGPYFLGRFLEALHYYSAIFDSLDSTFPPDSSQRAKVEQYIFAPEIRNIVACEGAERFERHERLEKWRKLMEGKGFKGVPLSANAVTQSKILLG-LYSCDGYRLTEDKGCLLLGWQDRAILAASAWRC 679          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV LL+ACAEAV   + + A AL+ ++   A+      ++VA+ F + LA R+  +           P N+ D +L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A+ + +  E+   V ++L +L    ++L   E + VNS+ +LH ++    GA+  VL +V ++ P+I+ +VEQ+++HNGP FL RF E+LHYYS +FDSL+  +    T+   M + Y  ++I N+++CEGP RVERHE + QWR R+  AGF  AP+ +  N    A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:  224 DSQENGIRLVHLLMACAEAVQESNFTLAEALVKQIGFLAVSQAGVMRKVATYFAEALARRIYKL----------CPQNSTDHSLS---DILQIHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGM----QWPALMQALALRPGGPPA-FRLTGIGPPAHDNTDHLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPTESVAVNSVFELHKLLSRP-GAIEKVLSVVKQMKPEIVTVVEQEANHNGPIFLDRFTESLHYYSTLFDSLEGSV---STQDKIMSEVYLGKQICNVVACEGPDRVERHETLTQWRTRLGSAGF--APVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWR 589          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKL--LDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV LL+ACAEAV   + + A AL+ ++   A+    + ++VA+ F + LA R+  + P           N+ D +L    + L++  YE CP+++F HF AN +ILEAFEG+  VHV+D  M  G+    QW  L+++LA R G PP+  R+TG+G       D++Q +G +L   A+ + +  E+   V ++L +L    ++L   + E + VNSI + H ++    GA+  VL +V ++ P+I+ +VEQ+++HNGP FL RF E+LHYYS +FDSL+  +    T+   M + Y A++I N+++CEG +RVERHE + QWR R+S AGF  AP+ +  N    A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:  224 DSQENGVRLVHLLMACAEAVQENNLNLAEALVKQIGFLAVSQAGAMRKVATYFAEALARRIYKLYP----------QNSTDHSLS---DILQIHFYETCPYLKFAHFTANQAILEAFEGKKRVHVIDFSMNQGM----QWPALMQALALRPGGPPA-FRLTGIGPPAHDNTDQLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPTEFESVAVNSIFEFHKLLAIP-GAMKKVLSVVKQMKPEIVTVVEQEANHNGPVFLDRFTESLHYYSTLFDSLEGSV---STQDKVMSEVYLAKQICNVVACEGSSRVERHETLTQWRTRLSSAGF--APVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWR 591          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPE--DIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEA+   +   A AL+  +   A     + ++VA+ F + LA R+  + P             +D  LD    + L +  YE CP+++F HF AN +ILEAF   S VHV+D G+  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A  +G+  EF   V S+L +L  E  D++  + E + VNS+ +LH ++ +  G ++ VL  +  + PKI+ +VEQ+++HNGP FL RF EALHYYS++FDSL+       ++   M + Y   +I N+++CEG  RVERHE + QWR R   AGF    +       A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:  228 DSQETGVRLVHTLLACAEAIQQENLKLADALVKHIGVLAASQAGAMRKVATYFAEALARRIYKIFP-------------QDHCLDSSYSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFGLKQGM----QWPALMQALALRPGGPPA-FRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVASSLADLEAEMLDLRPPEVEAVAVNSVFELHRLL-DRPGGIDKVLGSIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGVTPTSQDLVMSELYLGRQICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 599          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEV--LVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEA+   +   A AL+  +   A     + ++VA+ F + LA R+  + P             +D+ LD    + L +  YE CP+++F HF AN +ILEAF   S VHV+D G+  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A  +G+  EF   V ++L +L  E + LL  EV  + VNS+ +LH ++    G ++ VL+ +  + PKI+ +VEQ+++HNGP FL RF EALHYYS++FDSL+       ++   M + Y    I N+++CEG  RVERHE + QWR R   AGF    +       A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:   52 DSQETGVRLVHTLLACAEAIQQENLKLADALVKHIGLLAASQTGAMRKVATYFAEALARRIYKIFP-------------QDYCLDSSCSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFGLKQGM----QWPALMQALALRPGGPPA-FRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVANSLADLDAEMLGLLPPEVEAVAVNSVFELHRLLGRP-GGIDKVLESIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGLTPPSQDLVMSELYLGRHICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 423          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKK-EEALRL-VYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEV--LVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEA+   +   A AL+  +   A     + ++VA+ F + LA R+  + P             +D+ LD    + L +  YE CP+++F HF AN +ILEAF   S VHV+D G+  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A  +G+  EF   V ++L +L  E + LL  EV  + VNS+ +LH ++    G ++ VL+ +  + PKI+ +VEQ+++HNGP FL RF EALHYYS++FDSL+       ++   M + Y    I N+++CEG  RVERHE + QWR R   AGF    +       A   L      +GY + E  GCL+LGW ++P++A S W+
Sbjct:  228 DSQETGVRLVHTLLACAEAIQQENLKLADALVKHIGLLAASQTGAMRKVATYFAEALARRIYKIFP-------------QDYCLDSSCSDTLEMHFYETCPYLKFAHFTANQAILEAFANASRVHVIDFGLKQGM----QWPALMQALALRPGGPPA-FRLTGIGPPQPDNTDALQQVGWKLAQLAQTIGVEFEFRGFVANSLADLDAEMLGLLPPEVEAVAVNSVFELHRLLGRP-GGIDKVLESIKAMRPKIVTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSGLTPPSQDLVMSELYLGRHICNVVACEGADRVERHETLAQWRTRFDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGCLMLGWHTRPLIATSAWQ 599          

Query:  406 LVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVG------LYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNS---VLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            L + L  CA A+A  D      L+SELR    V G   QR+ +  ++GL  RLA      +   I + +  K+ A       + L+YE CP+ +FG+  AN +I +A + E  VH++D  +      G QW  LI++LA R G PP R+RITG+         G  + I+G  L   A+   +  EF     +   ++ E++ +  GE + VN  L LH +  ES G  N    +L++V  LSPK++ LVE +S+ N   F  RF+E L+YY AIF+S+D  LP+ + +R  +EQ   A E+ NI++CEG  RVERHE + +WR R   AGF   P+   VN+   +   N  E YT+ E  G L LGW ++P+VA+  W+
Sbjct:  163 LKEALCTCALAIANGDMFTVEWLMSELRQMVSVTGEPIQRLGAYMLEGLVARLA-----SSGSSIYNALRCKEPAGADLLSYMLLLYEACPYFKFGYMSANGAIADAMKDEISVHIIDFQIA----QGSQWVTLIQALAARPGGPP-RIRITGIDDSTSAYARGGGLDIVGKRLLKLAESYKVPFEFHTAGVSASEIQIENLGIQPGEAVAVNFALTLHHLPDESVGTQNHRDRLLRLVKSLSPKVVTLVEHESNTNTVPFFARFVETLNYYLAIFESIDVTLPRENKKRISVEQHCLAREVVNIVACEGAERVERHEPLGKWRSRFEMAGFTPYPLSSFVNSTIKILLENYSEKYTLEERDGALFLGWMNRPLVASCAWR 533          

Query:    1 MSAFDLISHSA---MSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLY-GGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            MS  DLI+HSA   M CY  P+ PLLEEG  +A T P  DESGNHKRLKRT SI++SMSSHNSLY GGGS +SC+T+ S+SR  STNSLNTLPRLHFRDHIWTYTQRYL         XX           D T  GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGS M+ KDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGES+VHVVDLGMTLGLPHGDQW GLIESLATR GQPP+RLRITGVGLYGDR+QIIG+ELEAYAD LGINLEFSVV SNLENLRP DIK+ DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEG    E  E VDQWRRRMSRAGFQAAPIKML  AKQWLGKI VCEGYTILEEKGCLVLGWKSKPIVAASCWKC
Sbjct:   22 MSVLDLITHSAASAMPCYPYPHTPLLEEGG-TASTPPXXDESGNHKRLKRTTSISDSMSSHNSLYSGGGSGDSCITDISLSRRSSTNSLNTLPRLHFRDHIWTYTQRYLAAEAVEEAAXXMSNAEGNEEEEDXTXXGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSAMSTKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGDQWXGLIESLATRTGQPPTRLRITGVGLYGDRLQIIGEELEAYADSLGINLEFSVVXSNLENLRPXDIKMYDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGRQGGEARE-VDQWRRRMSRAGFQAAPIKMLAQAKQWLGKIKVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 531          

Query:   10 FDLISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGG--GSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDG-TADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDK------KEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            FDL + S+MSC  +P +  LE+ +A+ ++ P++D++ NHKRLK+          H++ YG   G+N S    GS S    T+   +LP + FRDHI  + +RYL                       G + D ++LVQ LIACAEAVACRDK+HASALL ELRANA  FG+SFQRV+SCFVQGLA RLALVQPLGA G I   + +K F+ +K      K+EAL LVYEICP IQFGHFVAN+SILEAFEG S VHV+DLGMTLGL HG QWR LI+ LA R GQP   LRITGVG   +R+Q IGD+L+ +A  + IN +FS VESNLENL+P+D  L+DGE+L++NSILQLHC+VKESRG LNS LQ +HELSPK++VLVEQD+SHNGPFFLGRFMEALH YSAIFDSLDAMLPKYDTRR KMEQFYF EEIKNI+SCEGPARVERHERVDQWRRRM RAGFQ AP++ +  A +WL + N CEGYT++E+KGCLVLGWKSKPI+A SCWK
Sbjct:  452 FDL-NLSSMSCLPHPSLSALEDDSANWVS-PFVDKTRNHKRLKQ---------EHDANYGFKVGTNYSSFYTGSDSNM-CTSGFTSLPTIQFRDHISAHKRRYLAAEAMEEAFATLMRDKEDESEEGGGSEDEIKLVQQLIACAEAVACRDKAHASALLFELRANAQAFGTSFQRVSSCFVQGLAXRLALVQPLGAGGVIDPNVKSKPFSAEKGPFSAEKDEALHLVYEICPQIQFGHFVANASILEAFEGGSSVHVIDLGMTLGLQHGYQWRDLIDRLANRPGQPLHXLRITGVGSSSERLQAIGDDLKLHAQSMKINXDFSEVESNLENLKPQDFHLVDGEILIINSILQLHCLVKESRGTLNSALQTLHELSPKLMVLVEQDTSHNGPFFLGRFMEALHNYSAIFDSLDAMLPKYDTRRVKMEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMRRAGFQPAPLRTMAQAVKWL-ETNACEGYTVVEDKGCLVLGWKSKPIIATSCWK 951          

Query:  385 GTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVG-FIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGD--ELEAYADRLGINLEFSVVESNLEN--LRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G   G+ LV +L+ACAEAV CRD   A +LL+++ A+   +G S QRV+ CF  GL +RL+L+Q +   G F    M+    + D K EA +L+ +  P+I FG  VAN +I +A +G+  +H++DLGM     H  QW  LI +LA+R   PP +LRITG+    +  ++      L   A  LGI  EF ++   ++   L  E++   +GE L VNSI+ LH  VKESRG+L ++LQ + +L P +L LVEQD++HNGPFFLGRF+E+LH+YSAIFDSL+A LP+   +R K+E+ +FA+EI+NI++ EG  R+ERHER DQWRR++ RAGFQ   +K    A+  L  +  C+GYT+  EKGCL+LGWK +PI+ AS W+
Sbjct:  159 GVDQGLNLVHMLLACAEAVGCRDTKLADSLLAQIWASVSPWGDSLQRVSYCFAMGLKSRLSLLQNVNINGTFNNDMMDVSVTSRDDKLEAFQLLNQTTPYIAFGFMVANEAICQAAQGKEDLHIIDLGME----HTLQWPSLIRTLASRXEGPPKKLRITGLVEDHNLFELEAGMRALVEEASSLGIPTEFXLISEPVKPSLLTRENLDXREGEALFVNSIMHLHKYVKESRGSLKAILQALKKLGPSVLTLVEQDANHNGPFFLGRFLESLHFYSAIFDSLEASLPRNSPQRMKIERQHFADEIRNIVAFEGLNRIERHERADQWRRQLGRAGFQVMGLKCTSQARMML-SVYGCDGYTLASEKGCLLLGWKGRPIMLASAWQ 537          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALV---QPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            G++LV LL+ACAEAVA  D   A   L  L       G S QRVASCF + L+ RLA      P  +     SP     F + K     ++VY+ CP+I+F HF AN +I EAFE E  VHV+DL +  G     QW   +++LA R G  P  LRITGVG   + ++  G  L   A  L +  EF  V   LE+L+P       GE L VN++ +LH V   S   L ++L M+ + +P I+ LVEQ++SHNGP+FLGRF+EALHYYSAIFDSLDA  P    +RAK+EQ+ FA EI+NI++CEG  R ERHER+++WR+ M   GF++ P+    +  +K  LG +  C+GY + E+KGCL+LGW+ + I+AAS W+C
Sbjct: 1196 GLQLVHLLLACAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTEALSARLAATLTTTPSXSASKPFSPFPPNSFEILK---IYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDILQGY----QWPAFMQALAARPGGAPF-LRITGVGPCIEGVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLHRV---SVNCLGNLLAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGVERTERHERLEKWRKVMESKGFKSVPLSANAVTQSKILLG-LYSCDGYRMTEDKGCLLLGWQDRSIMAASAWRC 1564          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKE--EALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            G++L+ LL+ CAEAVA  D   A   L  L       G S QRVASCF   L+ RLA    L       +P     F  +  E  +  ++VY+ CP+I+F HF AN +I EAFE E  VHV+DL +  G     QW   +++LA R    P  LRITGVG   + ++  G  L   A  L +  EF  V   LE+L+P       GE L VN++ +LH V     G L   L M+ + +P I+ LVEQ++SHNGP+FLGRF+EALHYYSAIFDSLDA  P    +RAK+EQ+ FA EI+NI++CEG  R ERHER+++WR+ M   GF++  +    +  +K  LG +  C+GY + E+ GCL+LGW+ + I+AAS W+C
Sbjct:  328 GLQLLHLLLVCAEAVAKEDYMLARRYLHHLNRVVTPLGDSMQRVASCFTDALSARLAAT--LTTNPRASAPQPFSPFPPNSLEILKIYQIVYQACPYIKFAHFTANQAIFEAFESEERVHVIDLDILQGY----QWPAFMQALAARPSGAPF-LRITGVGPCIEAVKETGRCLTELALSLHVPFEFHAVGEQLEDLKPHMFNRRIGEALAVNTVNRLHRVPVNXLGNL---LAMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPDSAQRAKVEQYIFAPEIRNIVACEGAERTERHERLEKWRKVMESKGFKSVALSANAVTQSKILLG-LYSCDGYRMTEDNGCLLLGWQDRSIMAASAWRC 696          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPE--DIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAML-PKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G+RLV  L+ACAEAV   +   A AL+  +   A     + ++VA+ F + LA R+  + P   +    S +    F            YE CP+++F HF AN +ILEAF   S VHV+D G+  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A+ +G+  EF   V S+L +L P   DI+  +GEV+ VNS+ +LH ++    GA++ VL  +  + PKI+ +VEQ+++HNGP FL RF EALHYYS +FDSL+    P  D     M + Y   +I N+++CEG  RVERHE + QWR RM  AGF    +       A   L      +GY + E  G L+LGW ++P++A S W+
Sbjct:  210 DSQETGVRLVHTLMACAEAVQQENLKLADALVKHVGLLAASQTGAMRKVATYFAEALARRIYRIYPQDCLDSSYSDILEMHF------------YETCPYLKFAHFTANQAILEAFATASRVHVIDFGLKQGM----QWPALMQALALRPGGPPA-FRLTGIGPPQPDNTDALQQVGWKLAQLAETIGVEFEFRGFVASSLADLTPSMLDIRPSEGEVVAVNSVFELHRLLARP-GAVDKVLSSIKAMKPKIVTIVEQEANHNGPVFLDRFTEALHYYSNLFDSLEGSSGPSQD---LVMSEVYLGRQICNVMACEGGDRVERHETLSQWRGRMDSAGFDPVHLGSNAFKQASMLLALFAGGDGYRVEENNGSLMLGWHTRPLIATSAWQ 578          

Query:  397 GMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSS--FQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYG----DRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKES---RGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNA---KQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            G+RLV LL+ CAE+V   D + A +L+  ++A       S    +VA  F+  L+ R+   Q +G+    GS        + + E      YE CP+++F HF AN +ILEAF+G   VHV+D      L HG QW  LI++LA R G PP  LR+TG+G       D ++ IG  L   A  + +   F  V  S LE+++P  +++   E + VNSI+QLH ++         +  +L  +  L+PKI+ +VEQ++ HN P FL RF EAL+YYS +FDSL+A   + +   A   + Y   EI N++ CEG ARVERHE +D+WR R+ +AGF+  P+ +  NA      L  +   EGY + E +GCL LGW ++P++AAS W+
Sbjct:  154 GIRLVHLLVTCAESVQRGDLALAGSLIENMQALLTRVNPSCGIGKVAGYFIDALSCRIFSPQTVGSAS--GS--------VHENELLYHYFYEACPYLKFAHFTANQAILEAFDGHDCVHVIDFN----LMHGLQWPALIQALALRPGGPPL-LRLTGIGPPSPDGRDSLREIGLRLAELARSVNVRFXFRGVAASRLEDVKPWMLQVSPKEAVAVNSIMQLHRLLGSDPNRNSPIEMMLSWIRNLNPKIVAVVEQEADHNKPGFLDRFTEALYYYSNMFDSLEACAMQPEKALA---EIYIQREICNVVCCEGAARVERHEPLDKWRIRLEQAGFR--PLHLGSNAFKQASMLLTLFSAEGYRVEENQGCLTLGWHNRPLIAASAWQ 521          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAML-PKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPI--KMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D    G++LV  L+ACAEAV   +   A AL+  +   A       ++VA+ F + LA R+  + P   +    S +    F            YE CP+++F HF AN +ILEAF   + VHV+D G+  G+    QW  L+++LA R G PP   R+TG+G       D +Q +G +L   A+ +G+  EF   V ++L +L P  + +   E   VNS+ +LH ++  + GA++ VL  +  + PKI  +VEQ+++HNGP FL RF EALHYYS++FDSL+    P  D     M + Y   +I N+++CEG  RVERHE + QWR RM  AGF    +       A   L      +GY + E  G L+LGW ++P++  S WK
Sbjct:  208 DSQETGVQLVHTLMACAEAVQQENLKLADALVKHVGLLAAAQTGXMRKVATYFAEALARRIYRIYPQDCLDSSYSDILQMHF------------YETCPYLKFAHFTANQAILEAFATATRVHVIDFGLKQGM----QWPALMQALALRPGGPPV-FRLTGIGPPQPDNTDVLQQVGWKLAQLAETIGVEFEFRGFVANSLADLEPSMLDIRQDEAXAVNSVFKLHGLLARA-GAVDKVLSSIKAMKPKIXTIVEQEANHNGPVFLDRFTEALHYYSSLFDSLEGSSGPSQD---LVMSEVYLGRQICNVVACEGGDRVERHETLTQWRGRMDSAGFDPVHLGSNAFKQASMLLDLFAGVDGYRVQENNGSLMLGWHTRPLIVTSAWK 574          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLL--DGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEAV   + + A AL++++   A     + ++VA+ F + LA+R+  V P   +    S M    F            YE CP+++F HF AN +ILE+  G++ VHV+D  M  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A+ + +  E+   V ++L +L    ++L   + E + VNS+ +LH ++    GA+  VL +V ++ P+IL +VEQ+++HNGP F+ RF E+LHYYS +FDSL+      D     M + Y  ++I N+++CEG  RVERHE + QWR R   A F   P+ +  N    A   L      +GY + E  GCL+LGW ++P++A S WK
Sbjct:  259 DSQENGVRLVHGLMACAEAVQQNNFNLAKALVTQIGYLAGSQAGAMRKVATFFAEALAHRIFRVYPQPPIDHSFSDMLQMHF------------YETCPYLKFAHFTANQAILESLXGKTRVHVIDFSMNQGM----QWPALMQALALRPGGPPA-FRLTGIGPPASDNSDHLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELRPSEAESVAVNSVFELHKLLARP-GAIEKVLSVVKQMKPEILTVVEQEANHNGPVFMDRFNESLHYYSTLFDSLEGSANSQD---KVMSEVYLGKQICNVVACEGLDRVERHETLTQWRARFDSADF--VPVHLGSNAFKQASMLLALFAGGDGYRVEENDGCLMLGWHTRPLIATSAWK 626          

Query:  382 DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGL----YGDRMQIIGDELEAYADRLGINLEF-SVVESNLENLRPEDIKLLDGEV--LVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVN----AKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWK 1521
            D   +G+RLV  L+ACAEAV   + + A AL++++   A     + ++VA+ F + LA R+  V P   +    S M    F            YE CP+++F HF AN +ILE+ +G++ VHV+D  M  G+    QW  L+++LA R G PP+  R+TG+G       D +Q +G +L   A+ + +  E+   V ++L +L    ++L   EV  + VNS+ +LH ++    GA+  VL +V ++ P+I+ +VEQ+++HNGP F+ RF E+LHYYS +FDSL+      ++R   M + Y  ++I N+++CEG  RVERHE + QWR R   A F   P+ +  N    A   L      +GY + E  GC++L W ++P++A S WK
Sbjct:  260 DSQENGVRLVHGLMACAEAVQQNNFNLAKALVTQIGYLAGSQAGAMRKVATFFAEALAQRIFRVYPQSPIDHSFSDMLQMHF------------YETCPYLKFAHFTANQAILESLQGKTRVHVIDFSMNQGM----QWPALMQALALRPGGPPA-FRLTGIGPPASDNSDHLQEVGWKLAQLAETIHVEFEYRGFVANSLADLDASMLELGPSEVESVAVNSVFELHKLLARP-GAIEKVLSVVKQMKPEIVTVVEQEANHNGPVFMDRFNESLHYYSTLFDSLEG---SANSRDKVMSEVYLGKQICNVVACEGVDRVERHETLAQWRARFGSADF--VPVHLGSNAFKQASMLLALFAGGDGYRVEENDGCMMLAWHTRPLIATSAWK 627          

Query:   22 SHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S SA + YS  Y+P+ + G+A+   F Y DE+ NHKRLKRT SIAES+ S++SLY GG + S  ++  I+RS STNSLN+LPRLHFRDHIWTYTQRYL                      DG+ DGMRLVQLLIACAEAVACRDK+HAS+LLSELRANALVFGSSFQRVASCFVQGLA+RL+LVQPLGAVGFI   +N  D A +KKEEALRLVYEICPHI+FGHFVAN+SILEAFEGE++ HVVDLGMTLGL HG QWR LI SLA RAG+PP RLRITGVGL  DR +IIG+ELEAYA  L INLEFS VESNLENLRPEDIK  DGE LVVNSILQLHCVVKESRGALNSVLQ ++ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSL+AMLPKYDTRRAK+EQFYF EEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  AKQWLGK+  CEGY I+EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   20 SLSAQAYYSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIAESIGSNSSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWEKKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLEFSAVESNLENLRPEDIKREDGEALVVNSILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWKC 519          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSH-NSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S +AM+CY +PY+P+ E    S +  P+ DE+ + KR+K++ S+ ES+ S+ +SLY GGS        SI RS STNSLN +P+LHFRDHIWTYTQRYL                      +G +DGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGS+FQRVASCFVQGL +RL+LVQPLGAVGF+   MN  D A DKKEEALRLVYEICPHI+FGHFVAN+SILEAFEGES VHVVDLGMTLGLPHG QWR LI+SLA RAG+PPSRLRITGVGL  DR +IIGDELE YA  +GINLEFSVV+S+LENLRPEDIK  + EVLVVNSILQLHCVVKESRGALNSVLQ++ ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLD MLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQ APIKM+  AKQWL +  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLAAMACYPHPYLPIFESNVVSRM-LPFSDETRDVKRIKQSSSMVESIRSNGSSLYSGGS--------SICRSSSTNSLNNIPKLHFRDHIWTYTQRYLAAEAVEEAAAAMINAEEGGNEEEGNSDGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSAFQRVASCFVQGLIDRLSLVQPLGAVGFVAPTMNIIDIASDKKEEALRLVYEICPHIRFGHFVANNSILEAFEGESSVHVVDLGMTLGLPHGHQWRLLIQSLAERAGKPPSRLRITGVGLCVDRFRIIGDELEEYAKDMGINLEFSVVKSSLENLRPEDIKTSEDEVLVVNSILQLHCVVKESRGALNSVLQIILELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDTMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQVAPIKMMAQAKQWLVQSKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 516          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHK-RLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDG-TADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            IS SAM+ Y  PY+P+LE  N S     + DE+  HK R+KR +S AES  S      GGS +   +N +ISRS STNSLN+LPRLHFRDHIWTYTQRYL                      +G   DGMRLVQLLIACAEAVACRDKSHASALLSELR++ALVFGSSFQRVASCF QGLA+RL+LVQPLG V  +   MN  D A DKKEEAL LVYEICPHIQFGHFVANSSILEAFEGES+VHVVDLGMTLGLPHG QWR LI+SLA RAG+PP RLRIT VGL   R Q IGDEL  YA  +GINLEFSVVES LENL+P+DIK+ DGEVLVVNSILQLHCVVKESRGALNSVLQ +H LSPKIL LVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLP+YDTRRAKMEQFYFAEEIKNI+SCEGPARVERHE+VDQWRRRMSRAGFQAAP+KM+  AKQWLGK  VC+GYT++EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   24 ISLSAMAYYPYPYLPILEN-NESIFVLDFSDETREHKKRIKRALSFAESTGSDGIYNTGGSGSGSGSNDTISRSCSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEGAEAMANSEEGENHGEGGNTDGMRLVQLLIACAEAVACRDKSHASALLSELRSSALVFGSSFQRVASCFFQGLADRLSLVQPLGTVSLVTPIMNIMDIASDKKEEALSLVYEICPHIQFGHFVANSSILEAFEGESFVHVVDLGMTLGLPHGHQWRQLIQSLANRAGKPPCRLRITAVGLCVGRFQTIGDELVEYAKDVGINLEFSVVESTLENLQPDDIKVFDGEVLVVNSILQLHCVVKESRGALNSVLQTIHALSPKILALVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPRYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHEKVDQWRRRMSRAGFQAAPVKMMAQAKQWLGKNKVCDGYTVVEEKGCLVLGWKSKPIVAASCWKC 526          

Query:   19 ISHSAMSCYSNP-YMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNS-LYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXD-GTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S SAM+CY  P Y+P  +  NA +   P+ D++ + KR++R+ S+ ES+ S+NS LY GGS        SI RS STN LN++P+LHFRDHIWTYTQRYL                      + G ADGMRLVQLLIACAEAVACRDKSHASALLSELR+NALVFGSSFQRVASCFVQGL +RL+LVQPLGAVGF+ + MN  D A DKKEEALRLVYEICPHI+FGHFVAN++ILEAFEGES+VHVVDLGMTLGL HG QWR LIESLA RAG+ PSRLRITGVGL  DR +IIGDEL+ YA  +GINLEFS VESNLENLRPEDIK+ +GEVLVVNSILQLHCVVKESRGALNSVLQ+VHELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNI+SCEGPARVERHERV QWRRRMSRAGFQAAPIKM+  AKQWL K  VC+GYT++EEKGCLVLGWKSKPI+AASCWKC
Sbjct:   23 LSLSAMACYPRPPYLPTFDS-NAVSWILPFSDDTRDAKRMRRSSSLVESIRSNNSSLYSGGS--------SICRSISTNILNSIPKLHFRDHIWTYTQRYLAAEAVEEAASEAMINADEGGNEEEGNADGMRLVQLLIACAEAVACRDKSHASALLSELRSNALVFGSSFQRVASCFVQGLTDRLSLVQPLGAVGFVPT-MNIMDIASDKKEEALRLVYEICPHIRFGHFVANNAILEAFEGESFVHVVDLGMTLGLSHGHQWRRLIESLAERAGKAPSRLRITGVGLCVDRFRIIGDELKEYAKDMGINLEFSAVESNLENLRPEDIKINEGEVLVVNSILQLHCVVKESRGALNSVLQIVHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIVSCEGPARVERHERVYQWRRRMSRAGFQAAPIKMMAQAKQWLVKNKVCDGYTVVEEKGCLVLGWKSKPIIAASCWKC 517          

Query:   22 SHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S SA + YS  Y+P+ + G+A+   F Y DE+ NHKRLKRT SIAES+ S++SLY GG + S  ++  I+RS STNSLN+LPRLHFRDHIWTYTQRYL                      DG+ DGMRLVQLLIACAEAVACRDK+HAS+LLSELRANALVFGSSFQRVASCFVQGLA+RL+LVQPLGAVGFI   +N  D A +KKEEALRLVYEICPHI+FGHFVAN+SILEAFEGE++ HVVDLGMTLGL HG QWR LI SLA RAG+PP RLRITGVGL  DR +IIG+ELEAYA  L INL+                            ILQLHCVVKESRGALNSVLQ ++ELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSL+AMLPKYDTRRAK+EQFYF EEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  AKQWLGK+  CEGY I+EEKGCLVLGWKSKPIVAASCWKC
Sbjct:   20 SLSAQAYYSRSYLPIFQNGSATNW-FHYSDEARNHKRLKRTQSIAESIGSNSSLYSGGKSYSNSSSSFINRSSSTNSLNSLPRLHFRDHIWTYTQRYLAAEAVEEAAAAMISAAEGEVEEDGSGDGMRLVQLLIACAEAVACRDKTHASSLLSELRANALVFGSSFQRVASCFVQGLADRLSLVQPLGAVGFIAPSINPLDTAWEKKEEALRLVYEICPHIKFGHFVANASILEAFEGENFAHVVDLGMTLGLAHGQQWRQLIHSLANRAGRPPRRLRITGVGLCVDRFKIIGEELEAYAQDLDINLD----------------------------ILQLHCVVKESRGALNSVLQKINELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLEAMLPKYDTRRAKIEQFYFGEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMMAQAKQWLGKVKACEGYNIMEEKGCLVLGWKSKPIVAASCWKC 491          

Query:   28 SAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXX--DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDK-KEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            S + CY  PY+P++ + +A++     + +  + KRLKRTIS+           G GS  S     ++SRS ST+SL+ LPRL FRDHIWTYT+RYL                        DGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLA+RLA VQPLGAVG     MN  D A  + KEEA RLVYEICPHIQFGHFVANSSILEAFEGES VHVVDLGMTLGLP G QWR LIESLA RAGQPP RLRIT VGL  ++ Q IGDEL+ YA   GINLEFSVVESNLENL+ +DIK+L+ EVLVVNSILQLHCVVKESRGALNSVLQ++HELSPK+LVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDT+RAK+EQFYFAEEIKNI+SCEGPARVERHERVDQWRRRMSRAGFQAAPIKM+  A++WL    VCEGYT++EEKGCLVLGWKSKPI+A +CWKC
Sbjct:   29 SIVDCY--PYLPMMSDNSAAS---SMILQPRDQKRLKRTISV-----------GDGSPTS-----TLSRSSSTSSLSNLPRLQFRDHIWTYTRRYLAAEAVEEAAAAMIKSEDGCDGDQQDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLADRLASVQPLGAVGSFAPSMNIMDIAGSREKEEAFRLVYEICPHIQFGHFVANSSILEAFEGESLVHVVDLGMTLGLPRGQQWRRLIESLANRAGQPPRRLRITAVGLCVEKFQSIGDELKDYAKTYGINLEFSVVESNLENLQTKDIKVLENEVLVVNSILQLHCVVKESRGALNSVLQIIHELSPKVLVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTKRAKIEQFYFAEEIKNIVSCEGPARVERHERVDQWRRRMSRAGFQAAPIKMINQAQKWLKNNKVCEGYTVVEEKGCLVLGWKSKPIIATTCWKC 509          

Query:    7 AFDLISHSAMSCYSNPYMPLLEEGNASALT-FPYLDES--GNHKRLKRTISIAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSP-MNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRA-GQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            AFD+ + +  +    P+ P + E ++S L  FP+ D +   ++KR+KRT+           +Y   S +S     S SR       N++P+LHFRDHI TYTQRYL                      DG ADG+RLVQLLIACAEAVACRDKSHAS LLSEL+ANALVFGSSFQRVASCFVQGL  RL L+QP+G+ G + +P MN  D A D+ EEA RLVYE+CPHIQFGH++ANS++LEAFEGES+VHVVDLGM+LGL HG QWR LI+SLA RA G+   RLRITGVGL   R+Q IG+EL  YA+ LGINLEFSVV  NLENL+PEDI++ + EVLVVNSILQLHCVVKESRGALNSVLQM+H L PK+LV+VEQDSSHNGPFFLGRFME+LHYYS+IFDSLD MLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHERVDQWRRRMSRAGFQAAPIKM+  +KQWL K  VCEGYT++EEKGCLV GWKS+PIVA SCWKC
Sbjct:   20 AFDIWATNLWAYGYYPHQPAISENSSSKLVDFPFCDGTIIRDNKRVKRTVCFP--------IYNSVSCHSFFNTNSSSR-------NSIPKLHFRDHIRTYTQRYLAAEPVEEASEDTNSSESSGGEEDGCADGVRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLTERLNLIQPIGSAGPMMAPAMNIMDAASDEMEEAYRLVYELCPHIQFGHYLANSTVLEAFEGESFVHVVDLGMSLGLRHGHQWRALIQSLANRASGERVRRLRITGVGLCV-RLQTIGEELSVYANNLGINLEFSVVNKNLENLKPEDIEVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQSKQWLLKNKVCEGYTVVEEKGCLVFGWKSRPIVAVSCWKC 514          

Query:   52 PYMPLLEEGNASALT-FPYLDES--GNHKRLKRTIS--IAESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVG-FIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAG-QPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            P+ P+ E  + S L  FP+ D +   ++KR+KRT+   I  S++ H+            TN S SR       N++P+LHFRDHI TYTQRYL                      DG ADG+RLVQLLIACAEAVACRDKSHAS LLSEL+ANALVFGSSFQRVASCFVQGL  RL L+QP+G  G  + S MN  D A D+ EEA RLVYE+CPHIQFGH++ANS+ILEAFEGES+VHVVDLGM+LGL HG QWRGLI++LA R G +   RLRITGVGL  +R+Q IG+EL  YA+ LG+NLEFSVVE NLENL+PEDIK+ + EVLVVNSILQLHCVVKESRGALNSVLQM+H L PK+LV+VEQDSSHNGPFFLGRFME+LHYYS+IFDSLD MLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHERVDQWRRRMSRAGFQAAPIKM+  AKQWL K  VCEGYT++EEKGCLVLGWKS+PIVA SCWKC
Sbjct:   35 PHQPISEINSTSTLVDFPFCDGTIVRDNKRVKRTVCFPIYNSINCHSFFN---------TNNSSSR-------NSIPKLHFRDHIRTYTQRYLAAEPVEDTNSSESSGGEE----DGCADGVRLVQLLIACAEAVACRDKSHASILLSELKANALVFGSSFQRVASCFVQGLIERLNLIQPIGPAGPMMPSMMNIMDVASDEMEEAFRLVYELCPHIQFGHYLANSTILEAFEGESFVHVVDLGMSLGLRHGHQWRGLIQNLAGRVGGERVRRLRITGVGLC-ERLQTIGEELSVYANNLGVNLEFSVVEKNLENLKPEDIKVREEEVLVVNSILQLHCVVKESRGALNSVLQMIHGLGPKVLVMVEQDSSHNGPFFLGRFMESLHYYSSIFDSLDVMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHERVDQWRRRMSRAGFQAAPIKMVAQAKQWLLKNKVCEGYTVVEEKGCLVLGWKSRPIVAVSCWKC 511          

Query:   52 PYMPLLEEGNASA-LTFPYLDESG----NHKRLKR-TISIA---ESMSSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGT-ADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLG---AVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            P +P+LE    S  +  P+ D       +HK+LKR T++I     + SSH++ +    N++             NS+N++PRLHFRDHI TY QRY                       DG+ ADGMRLVQLLIACAEAVACRDKSHAS LLSEL++NALVFGSSFQRVASCFVQGL  RL L+QP+G   A     S MN  D A ++ EEA +LVYE CPHIQFGHFVANS ILEAFEGES++HVVDLGM+LGLPHG QWRGLI+SLA R+     RLRIT +GL   R+Q+IG+EL  YA  LGI+LEFS+VE NLENL+P+DIK+ + EVLVVNSILQLHCVVKESRGALN+VLQM+H LSPK+LV+ EQDS HNGPFFLGRFME+LHYYSAIFDSLDAMLPKYDT+RAKMEQFYFAEEIKNI+SCEGP R+ERHE+VDQWRRRMSRAGFQ +PIKM+V AKQWL K NVC+GYT++EEKGCLVLGWKSKPIVA SCWKC
Sbjct:   30 PNLPILENSATSTWILNPFSDHETETIRDHKKLKRSTVTIPIWFANFSSHSNSFFNNINSN------------NNSVNSIPRLHFRDHIRTYKQRYFASEAVEEAAEDNFNYNNCEAEEDGSCADGMRLVQLLIACAEAVACRDKSHASVLLSELKSNALVFGSSFQRVASCFVQGLTERLTLIQPIGNNSAGSDTKSMMNIMDAASEEMEEAFKLVYENCPHIQFGHFVANSIILEAFEGESFLHVVDLGMSLGLPHGHQWRGLIQSLADRSSHRVRRLRITAIGLCIARIQVIGEELSIYAKNLGIHLEFSIVEKNLENLKPKDIKVNEKEVLVVNSILQLHCVVKESRGALNAVLQMIHGLSPKVLVMAEQDSGHNGPFFLGRFMESLHYYSAIFDSLDAMLPKYDTKRAKMEQFYFAEEIKNIVSCEGPLRMERHEKVDQWRRRMSRAGFQGSPIKMVVQAKQWLVKNNVCDGYTVVEEKGCLVLGWKSKPIVAVSCWKC 521          

Query:   19 ISHSAMSCYSNPYMPLLEEGNASALTFPYLDESGNHKRLKRTISIAESM--SSHNSLYGGGSNNSCVTNGSISRSGSTNSLNTLPRLHFRDHIWTYTQRYLXXXXXXXXXXXXXXXXXXXXXXDGTADGMRLVQLLIACAEAVACRDKSHASALLSELRANALVFGSSFQRVASCFVQGLANRLALVQPLGAVGFIGSPMNAKDFALDKKEEALRLVYEICPHIQFGHFVANSSILEAFEGESYVHVVDLGMTLGLPHGDQWRGLIESLATRAGQPPSRLRITGVGLYGDRMQIIGDELEAYADRLGINLEFSVVESNLENLRPEDIKLLDGEVLVVNSILQLHCVVKESRGALNSVLQMVHELSPKILVLVEQDSSHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGPARVERHERVDQWRRRMSRAGFQAAPIKMLVNAKQWLGKINVCEGYTILEEKGCLVLGWKSKPIVAASCWKC 1524
            +S SAM+    P +  L +  +S    P+ D + NHKRLKR +   +S+  +S++SLY  G N            G TNSLN+L  L ++DHIW   QRYL                      +G+ DGM+LV  LI CA+ VA RDKSHASALLSELRANALVFG+SFQRVASCFVQGL++RL+L+Q LGAVG  G  +   D    +KEEA RL +EICP IQFGH  AN+SILEAFEGES VHVVDLGM LG P G QWR L+ SLA RAG+PPS L+ITGVG   + ++ I DELE YA+ LG+N +FS+VESNLENL+PEDI LL+GE +VVNSILQLHCVVKESRGALNSVLQ + ELSPK +VLVEQD+SHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEG ARVERH+R+DQWRRRMSRAGFQ++P+KM+  AKQWL K+ +C+GYTI++EKGCLVLGWKSKPI+AASCWKC
Sbjct:   40 LSLSAMAGCPFPCLATLMD-ISSTWFIPFSDATRNHKRLKRGLGTDQSIRSNSYSSLYDDGCN------------GRTNSLNSLLGLQYQDHIWGNAQRYLAVEAIAVDAAAMLGGGVDAVLKEGSDDGMKLVHQLITCAKVVAFRDKSHASALLSELRANALVFGTSFQRVASCFVQGLSDRLSLIQSLGAVGVGGCTVKTMDIT-PEKEEAFRLFFEICPQIQFGHLAANASILEAFEGESSVHVVDLGMNLGSPQGQQWRSLMHSLANRAGKPPSSLQITGVGTAAECLKDIIDELEVYAESLGMNFQFSMVESNLENLQPEDINLLEGEAVVVNSILQLHCVVKESRGALNSVLQKIRELSPKAVVLVEQDASHNGPFFLGRFMEALHYYSAIFDSLDAMLPKYDTRRAKMEQFYFAEEIKNIISCEGSARVERHQRLDQWRRRMSRAGFQSSPMKMITEAKQWLEKVKLCDGYTIVDEKGCLVLGWKSKPIIAASCWKC 529